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Hydra Magnipapillata
''Hydra vulgaris'', the fresh-water polyp, is a small animal freshwater hydroid with length from 10 mm to 30 mm and width about 1 mm. Description The hydra have four to twelve tentacles that protrude from just outside the mouth. They feed by extending their tentacles and waiting for food to touch the tentacles. They then bring the food to their mouth, ingest and digest the organism. Anything that cannot be digested is egested. Ingestion and egestion occur through the mouth. Like other hydras, ''Hydra vulgaris'' cling to a base object with a "foot" pad, shaped like a disk. The ''Hydra'' moves by releasing its grip on its base and is carried away by the current. ''H. vulgaris'' can also move by bending over, grabbing a surface with its tentacles, releasing its grip with its "foot" and flipping over itself. Model organism ''H. vulgaris'' is often used, like many hydra, as a model organism for morphallactic regeneration because they are easy to care for, requiring minimal dir ...
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Peter Simon Pallas
Peter Simon Pallas Fellow of the Royal Society, FRS FRSE (22 September 1741 – 8 September 1811) was a Prussian zoologist and botanist who worked in Russia between 1767 and 1810. Life and work Peter Simon Pallas was born in Berlin, the son of Professor of Surgery Simon Pallas. He studied with private tutors and took an interest in natural history, later attending the University of Halle and the University of Göttingen. In 1760, he moved to the University of Leiden and passed his doctor's degree at the age of 19. Pallas travelled throughout the Netherlands and to London, improving his medical and surgical knowledge. He then settled at The Hague, and his new system of animal classification was praised by Georges Cuvier. Pallas wrote ''Miscellanea Zoologica'' (1766), which included descriptions of several vertebrates new to science which he had discovered in the Dutch museum collections. A planned voyage to southern Africa and the East Indies fell through when his father reca ...
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Hydroid (zoology)
Hydroids are a life stage for most animals of the class Hydrozoa, small predators related to jellyfish. Some hydroids such as the freshwater '' Hydra'' are solitary, with the polyp attached directly to the substrate. When these produce buds, they become detached and grow on as new individuals. The majority of hydroids are colonial. The original polyp is anchored to a solid substrate and forms a bud which remains attached to its parent. This in turn buds and in this way a stem is formed. The arrangement of polyps and the branching of the stem is characteristic of the species. Some species have the polyps budding directly off the stolon which roots the colony. The polyps are connected by epidermis which surrounds a gastrovascular cavity. The epidermis secretes a chitinous skeleton which supports the stem and in some hydroids, the skeleton extends into a cup shape surrounding the polyp. Most of the polyps are gastrozooids or feeding polyps, but some are specialised reprodu ...
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Tentacle
In zoology, a tentacle is a flexible, mobile, and elongated organ present in some species of animals, most of them invertebrates. In animal anatomy, tentacles usually occur in one or more pairs. Anatomically, the tentacles of animals work mainly like muscular hydrostats. Most forms of tentacles are used for grasping and feeding. Many are sensory organs, variously receptive to touch, vision, or to the smell or taste of particular foods or threats. Examples of such tentacles are the eyestalks of various kinds of snails. Some kinds of tentacles have both sensory and manipulatory functions. A tentacle is similar to a cirrus, but a cirrus is an organ that usually lacks the tentacle's strength, size, flexibility, or sensitivity. A nautilus has cirri, but a squid has tentacles. Invertebrates Molluscs Many molluscs have tentacles of one form or another. The most familiar are those of the pulmonate land snails, which usually have two sets of tentacles on the head: when extended ...
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Model Organism
A model organism (often shortened to model) is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. Model organisms are widely used to research human disease when human experimentation would be unfeasible or unethical. This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution. Studying model organisms can be informative, but care must be taken when generalizing from one organism to another. In researching human disease, model organisms allow for better understanding the disease process without the added risk of harming an actual human. The species chosen will usually meet a determined taxonomic equivalency to humans, so as to react to disease or its treatment in a way that resembles ...
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Morphallaxis
Morphallaxis is the regeneration of specific tissue in a variety of organisms due to loss or death of the existing tissue. The word comes from the Greek ''allazein,'' (αλλάζειν) which means ''to change.'' The classical example of morphallaxis is that of the Cnidarian hydra, where when the animal is severed in two (by actively cutting it with, for example, a surgical knife) the remaining severed sections form two fully functional and independent hydra. The notable feature of morphallaxis is that a large majority of regenerated tissue comes from already-present tissue in the organism. That is, the one severed section of the hydra forms into a smaller version of the original hydra, approximately the same size as the severed section. Hence, there is an "exchange" of tissue. Researchers Wilson and Child showed circa 1930 that if the hydra was pulped and the disassociated food passed through a sieve, those cells then put into an aqueous solution would shortly reform into the ...
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Senescence
Senescence () or biological aging is the gradual deterioration of functional characteristics in living organisms. The word ''senescence'' can refer to either cellular senescence or to senescence of the whole organism. Organismal senescence involves an increase in death rates and/or a decrease in fecundity with increasing age, at least in the latter part of an organism's life cycle. Senescence is the inevitable fate of almost all multicellular organisms with germ-soma separation, but it can be delayed. The discovery, in 1934, that calorie restriction can extend lifespan by 50% in rats, and the existence of species having negligible senescence and potentially immortal organisms such as '' Hydra'', have motivated research into delaying senescence and thus age-related diseases. Rare human mutations can cause accelerated aging diseases. Environmental factors may affect aging – for example, overexposure to ultraviolet radiation accelerates skin aging. Different parts of the body ...
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Biological Immortality
Biological immortality (sometimes referred to as bio-indefinite mortality) is a state in which the rate of mortality from senescence is stable or decreasing, thus decoupling it from chronological age. Various unicellular and multicellular species, including some vertebrates, achieve this state either throughout their existence or after living long enough. A biologically immortal living being can still die from means other than senescence, such as through injury, poison, disease, predation, lack of available resources, or changes to environment. This definition of immortality has been challenged in the ''Handbook of the Biology of Aging'', because the increase in rate of mortality as a function of chronological age may be negligible at extremely old ages, an idea referred to as the late-life mortality plateau. The rate of mortality may cease to increase in old age, but in most cases that rate is typically very high. The term is also used by biologists to describe cells that are not ...
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Rafael Yuste
Rafael Yuste (born April 25, 1963 in Madrid) is a Spanish-American neurobiologist and one of the initiators of the BRAIN Initiative announced in 2013. He is currently a professor at Columbia University. Biography Yuste's interest in neuroscience arose early, inspired by books like Santiago Ramón y Cajal's ''Los Tónicos de la Voluntad: Reglas y consejos sobre investigación científica'' ) (''The Tonics of the Will: Rules and Advice on Scientific Research'') and supported by his parents. He studied medicine at the Universidad Autónoma de Madrid and its Fundación Jiménez Díaz Hospital (1982–1987). Finding the treatment and understanding of mental diseases as "primitive", Yuste decided that instead of practicing medicine he would work on laying the scientific basis for future treatments through basic biological research. He worked for two summers (1985/86) in the laboratory of the Nobel laureate Sydney Brenner at the University of Cambridge, but the budget cuts of Margaret T ...
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Sexual Reproduction
Sexual reproduction is a type of reproduction that involves a complex life cycle in which a gamete ( haploid reproductive cells, such as a sperm or egg cell) with a single set of chromosomes combines with another gamete to produce a zygote that develops into an organism composed of cells with two sets of chromosomes ( diploid). This is typical in animals, though the number of chromosome sets and how that number changes in sexual reproduction varies, especially among plants, fungi, and other eukaryotes. Sexual reproduction is the most common life cycle in multicellular eukaryotes, such as animals, fungi and plants. Sexual reproduction also occurs in some unicellular eukaryotes. Sexual reproduction does not occur in prokaryotes, unicellular organisms without cell nuclei, such bacteria and archaea. However, some process in bacteria may be considered analogous to sexual reproduction in that they incorporate new genetic information, including bacterial conjugation, transformatio ...
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Budding
Budding or blastogenesis is a type of asexual reproduction in which a new organism develops from an outgrowth or bud due to cell division at one particular site. For example, the small bulb-like projection coming out from the yeast cell is known as a bud. Since the reproduction is asexual, the newly created organism is a clone and excepting mutations is genetically identical to the parent organism. Organisms such as hydra use regenerative cells for reproduction in the process of budding. In hydra, a bud develops as an outgrowth due to repeated cell division at one specific site. These buds develop into tiny individuals and, when fully mature, detach from the parent body and become new independent individuals. Internal budding or endodyogeny is a process of asexual reproduction, favored by parasites such as ''Toxoplasma gondii''. It involves an unusual process in which two daughter cells are produced inside a mother cell, which is then consumed by the offspring prior to their s ...
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Regeneration (biology)
In biology, regeneration is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can either be complete where the new tissue is the same as the lost tissue, or incomplete where after the necrotic tissue comes fibrosis. At its most elementary level, regeneration is mediated by the molecular processes of gene regulation and involves the cellular processes of cell proliferation, morphogenesis and cell differentiation. Regeneration in biology, however, mainly refers to the morphogenic processes that characterize the phenotypic plasticity of traits allowing multi-cellular organisms to repair and maintain the integrity of their physiological and morphological states. Above the genetic level, regeneration is fundamentally regulated by asexual cellular processes. Regeneration ...
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