Hoxa Sound
Hoxa may refer to: *Hoxa, one of the four clusters in which Hox genes are arranged in higher vertebrates, or one of the following genes associated with it: **HOXA9 **HOXA11 ** HOXA11-AS1 (gene) **HOXA13 *HOXA, the Hazaribagh Old Xaverians Association, the official alumni organization for St. Xavier's School in Hazaribagh, Jharkhand, India * Hoxa, Orkney, settlement on South Ronaldsay in the Orkney Islands See also *Enver Hoxha Enver Halil Hoxha ( , ; 16 October 190811 April 1985) was an Albanian communist politician who was the authoritarian ruler of Albania from 1944 until his death in 1985. He was First Secretary of the Party of Labour of Albania from 1941 unt ...

Hox Gene
Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body. For example, Hox genes in insects specify which appendages form on a segment (for example, legs, antennae, and wings in fruit flies), and Hox genes in vertebrates specify the types and shape of vertebrae that will form. In segmented animals, Hox proteins thus confer segmental or positional identity, but do not form the actual segments themselves. Studies on Hox genes in ciliated larvae have shown they are only expressed in future adult tissues. In larvae with gradual metamorphosis the Hox genes are activated in tissues of the larval body, generally in the trunk region, that will be maintained through metamorphosis. In larvae with complete metamorphosis the Hox genes are mainly express ...
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HOXA9
Homeobox protein Hox-A9 is a protein that in humans is encoded by the ''HOXA9'' gene. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of ''Drosophila'' fly. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. As HOXA9 dysfunction has been implicated in acute myeloid leukemia, and expression of the gene has been shown to differ markedly between erythrocyte lineages of different stages of development, the gene is of particular interest from a hematopoietic persp ...
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HOXA11
Homeobox protein Hox-A11 is a protein that in humans is encoded by the ''HOXA11'' gene. Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radioulnar synostosis Radioulnar synostosis is a rare condition where there is an abnormal connection between the radius and ulna bones of the forearm. This can be present at birth (congenital), when it is a result of a failure of the bones to form separately, or follo ... with amegakaryocytic thrombocytopenia. See also * ...
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HOXA11-AS1 (gene)
HOXA11-AS lncRNA is a long non-coding RNA from the antisense strand in the homeobox A (HOXA11, HOXA gene). The HOX gene contains four clusters (A, B, C, and D). The sense strand of the HOXA gene codes for proteins. Alternative names for HOXA11-AS lncRNA are: HOXA-AS5, HOXA11S, HOXA11-AS1, HOXA11AS, or NCRNA00076. This gene is 3,885 nucleotides long and resides at Chromosome 7 (human), chromosome 7 (7p15.2) and is transcribed from an independent Promoter (genetics), gene promoter. Being a lncRNA, it is longer than 200 nucleotides in length, in contrast to regular non-coding RNAs. The HOX genes code for transcription factors that are key to embryonic development. This lncRNA is one of the three lncRNAs present in the 5-prime region of the HOXA11 gene. The other two lncRNAs are HOXA10-AS and HOTTIP. Of these lncRNAs, HOXA11-AS, is the most conserved sequence in a wide range of organisms, which shows its longevity in the phylogenetic tree. Since HOX genes play a prominent role in embryo ...
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HOXA13
Homeobox protein Hox-A13 is a protein that in humans is encoded by the ''HOXA13'' gene. Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and Cellular differentiation, differentiation. Clinical significance Expansion of a polyalanine tract in the encoded protein can cause Hand-Foot-Genital Syndrome, hand-foot-genital syndrome, also known as hand-foot-uterus syndrome. Aberrant expression of ''HoxA13'' gene products in the esophagus, provokes Barrett’s esophagus, a form of metaplasia that is a direct precursor to esophageal cancer. See also * Homeobox References Further reading * * * * * * * ...
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Hoxa, Orkney
Hoxa is a small settlement on the island of South Ronaldsay in the Orkney Islands north of mainland Scotland. Hoxa is located west of St Margaret's Hope at the end of the B9043 road. Thorfinn Turf-Einarsson the 10th century Norse Earl of Orkney (aka Thorfinn Skullsplitter) may be buried at the site of The Howe broch A broch is an Iron Age drystone hollow-walled structure found in Scotland. Brochs belong to the classification "complex Atlantic roundhouse" devised by Scottish archaeologists in the 1980s. Their origin is a matter of some controversy. Origin ... just north of Hoxa.Wenham, Sheena "The South Isles" in Omand, Donald (ed.) (2003) The Orkney Book. Edinburgh. Birlinn. pp. 211-12 References External links The Megalithic Portal - Howe of HoxaCanmore - Hoxa Head Balfour Battery site recordNorthern Lighthouse Board Villages in Orkney Orkneyinga saga places {{Orkney-geo-stub ...
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