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Horizontal Transmission
Horizontal transmission is the transmission of organisms between biotic and/or abiotic members of an ecosystem that are not in a parent-progeny relationship. This concept has been generalized to include transmissions of infectious agents, symbionts, and cultural traits between humans. Because the evolutionary fate of the agent is not tied to reproductive success of the host, horizontal transmission tends to evolve virulence. It is therefore a critical concept for evolutionary medicine. Biological Pathogen transmission In biological, but not cultural, transmissions the carriers (also known as vectors) may include other species. The two main biological modes of transmission are ''anterior station'' and ''posterior station''. In anterior station, transmission occurs via the bite of an infected organism (the vector), like in malaria, dengue fever, and bubonic plague. Posterior station is transmission via contact with infected feces. Examples are rickettsiae driven diseases (l ...
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Evolution
Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation tends to exist within any given population as a result of genetic mutation and recombination. Evolution occurs when evolutionary processes such as natural selection (including sexual selection) and genetic drift act on this variation, resulting in certain characteristics becoming more common or more rare within a population. The evolutionary pressures that determine whether a characteristic is common or rare within a population constantly change, resulting in a change in heritable characteristics arising over successive generations. It is this process of evolution that has given rise to biodiversity at every level of biological organisation, including the levels of species, individual organisms, and molecules. The theory of evolution by ...
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Germ Cell
Germ or germs may refer to: Science * Germ (microorganism), an informal word for a pathogen * Germ cell, cell that gives rise to the gametes of an organism that reproduces sexually * Germ layer, a primary layer of cells that forms during embryonic development * Cereal germ, the reproductive part of a cereal grain * Tooth germ, an aggregation of cells that eventually forms a tooth * Germ theory of disease, which states that some diseases are caused by microorganisms * Germ (mathematics), an object in a topological space that captures local properties Art and media Music * Germs (band), an American punk rock band * Germ (musician), a stage name of Tim Wright * Germ (rapper), an American rapper affiliated with Suicideboys and Pouya * "Germs" (song), by "Weird Al" Yankovic * ''The Germ'' (album), by Victim's Family Others * "Germs" (''Invader Zim''), an episode of ''Invader Zim'' * ''The Germ'' (periodical), a British art magazine published in 1850 * The Germs (comics) ...
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Dual Inheritance Theory
Dual inheritance theory (DIT), also known as gene–culture coevolution or biocultural evolution, was developed in the 1960s through early 1980s to explain how human behavior is a product of two different and interacting evolutionary processes: genetic evolution and cultural evolution. Genes and culture continually interact in a feedback loop, changes in genes can lead to changes in culture which can then influence genetic selection, and vice versa. One of the theory's central claims is that culture evolves partly through a Darwinian selection process, which dual inheritance theorists often describe by analogy to genetic evolution. 'Culture', in this context is defined as 'socially learned behavior', and 'social learning' is defined as copying behaviors observed in others or acquiring behaviors through being taught by others. Most of the modelling done in the field relies on the first dynamic (copying) though it can be extended to teaching. Social learning at its simplest involves ...
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Reification (statistics)
In statistics, reification is the use of an idealized model of a statistical process. The model is then used to make inferences connecting model results, which imperfectly represent the actual process, with experimental observations. Also, Everitt,2002 a process whereby model-derived quantities such as principal components, factors and latent variable In statistics, latent variables (from Latin: present participle of ''lateo'', “lie hidden”) are variables that can only be inferred indirectly through a mathematical model from other observable variables that can be directly observed or me ...s are identified, named and treated as if they were directly measurable quantities. Notes References * Everitt, B.S. (2002) Cambridge Dictionary of Statistics (2nd Edition), CUP. Multivariate statistics Statistical models {{statistics-stub ...
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Nitrogen Fixation
Nitrogen fixation is a chemical process by which molecular nitrogen (), with a strong triple covalent bond, in the air is converted into ammonia () or related nitrogenous compounds, typically in soil or aquatic systems but also in industry. Atmospheric nitrogen is molecular dinitrogen, a relatively nonreactive molecule that is metabolically useless to all but a few microorganisms. Biological nitrogen fixation or ''diazotrophy'' is an important microbials mediated process that converts dinitrogen (N2) gas to ammonia (NH3) using the nitrogenase protein complex (Nif). Nitrogen fixation is essential to life because fixed inorganic nitrogen compounds are required for the biosynthesis of all nitrogen-containing organic compounds, such as amino acids and proteins, nucleoside triphosphates and nucleic acids. As part of the nitrogen cycle, it is essential for agriculture and the manufacture of fertilizer. It is also, indirectly, relevant to the manufacture of all nitrogen chemical c ...
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Symbiosome
A symbiosome is a specialised compartment in a host cell that houses an endosymbiont in a symbiotic relationship. The term was first used in 1983 to describe the vacuole structure in the symbiosis between the animal host the '' Hydra'', and the endosymbiont ''Chlorella''. Symbiosomes are also seen in other cnidaria-dinoflagellate symbioses, including those found in coral-algal symbioses. In 1989 the concept was applied to the similar structure found in the nitrogen-fixing root nodules of certain plants. The symbiosome in the root nodules has been much more successfully researched due in part to the complexity of isolating the symbiosome membrane in animal hosts. The symbiosome in a root nodule cell in a plant is an organelle-like structure that has formed in a symbiotic relationship with nitrogen-fixing bacteria. The plant symbiosome is unique to those plants that produce root nodules. The majority of such symbioses are made between legumes and diazotrophic ''Rhizobia'' bacteria. T ...
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Root Nodule
Root nodules are found on the roots of plants, primarily legumes, that form a symbiosis with nitrogen-fixing bacteria. Under nitrogen-limiting conditions, capable plants form a symbiotic relationship with a host-specific strain of bacteria known as rhizobia. This process has evolved multiple times within the legumes, as well as in other species found within the Rosid clade. Legume crops include beans, peas, and soybeans. Within legume root nodules, nitrogen gas (N2) from the atmosphere is converted into ammonia (NH3), which is then assimilated into amino acids (the building blocks of proteins), nucleotides (the building blocks of DNA and RNA as well as the important energy molecule ATP), and other cellular constituents such as vitamins, flavones, and hormones. Their ability to fix gaseous nitrogen makes legumes an ideal agricultural organism as their requirement for nitrogen fertilizer is reduced. Indeed, high nitrogen content blocks nodule development as there is no benefit ...
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Lipooligosaccharide
Lipopolysaccharides (LPS) are large molecules consisting of a lipid and a polysaccharide that are bacterial toxins. They are composed of an O-antigen, an outer core, and an inner core all joined by a covalent bond, and are found in the outer membrane of Gram-negative bacteria. Today, the term ''endotoxin'' is often used synonymously with LPS, although there are a few endotoxins (in the original sense of toxins that are inside the bacterial cell that are released when the cell disintegrates) that are not related to LPS, such as the so-called delta endotoxin proteins produced by ''Bacillus thuringiensis''. Lipopolysaccharides can have substantial impacts on human health, primarily through interactions with the immune system. LPS is a potent activator of the immune system and pyrogen (agent that causes fever). In severe cases, LPS can play a role in causing septic shock. In lower levels and over a longer time period, there is evidence LPS may play an important and harmful role in ...
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Flavonoid
Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and a heterocyclic ring (C, the ring containing the embedded oxygen). This carbon structure can be abbreviated C6-C3-C6. According to the IUPAC nomenclature, they can be classified into: *flavonoids or bioflavonoids *isoflavonoids, derived from 3-phenyl chromen-4-one (3-phenyl-1,4-benzopyrone) structure *neoflavonoids, derived from 4-phenylcoumarine (4-phenyl-1,2-benzopyrone) structure The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins ( flavones and flavonols). This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavonoid have also been more loosely used to describe non ...
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Legume
A legume () is a plant in the family Fabaceae (or Leguminosae), or the fruit or seed of such a plant. When used as a dry grain, the seed is also called a pulse. Legumes are grown agriculturally, primarily for human consumption, for livestock forage and silage, and as soil-enhancing green manure. Well-known legumes include beans, soybeans, chickpeas, peanuts, lentils, lupins, mesquite, carob, tamarind, alfalfa, and clover. Legumes produce a botanically unique type of fruit – a simple dry fruit that develops from a simple carpel and usually dehisces (opens along a seam) on two sides. Legumes are notable in that most of them have symbiotic nitrogen-fixing bacteria in structures called root nodules. For that reason, they play a key role in crop rotation. Terminology The term ''pulse'', as used by the United Nations' Food and Agriculture Organization (FAO), is reserved for legume crops harvested solely for the dry seed. This excludes green beans and green peas, which a ...
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Rhizobia
Rhizobia are diazotrophic bacteria that fix nitrogen after becoming established inside the root nodules of legumes (Fabaceae). To express genes for nitrogen fixation, rhizobia require a plant host; they cannot independently fix nitrogen. In general, they are gram negative, motile, non-sporulating rods. Rhizobia are a "group of soil bacteria that infect the roots of legumes to form root nodules". Rhizobia are found in the soil and after infection, produce nodules in the legume where they fix nitrogen gas (N2) from the atmosphere turning it into a more readily useful form of nitrogen. From here, the nitrogen is exported from the nodules and used for growth in the legume. Once the legume dies, the nodule breaks down and releases the rhizobia back into the soil where they can live individually or reinfect a new legume host. History The first known species of rhizobia, '' Rhizobium leguminosarum'', was identified in 1889, and all further species were initially placed in the ''Rhiz ...
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Holobiont
A holobiont is an assemblage of a host and the many other species living in or around it, which together form a discrete ecological unit through symbiosis, though there is controversy over this discreteness. The components of a holobiont are individual species or bionts, while the combined genome of all bionts is the hologenome. The holobiont concept was initially introduced by the German theoretical biologist Adolf Meyer-Abich in 1943, and then apparently independently by Dr. Lynn Margulis in her 1991 book ''Symbiosis as a Source of Evolutionary Innovation''. The concept has evolved since the original formulations. Holobionts include the host, virome, microbiome, and any other organisms which contribute in some way to the functioning of the whole. Well-studied holobionts include reef-building corals and humans. Overview A holobiont is a collection of closely associated species that have complex interactions, such as a plant species and the members of its microbiome. Each sp ...
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