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History Of Model Organisms
The history of model organisms began with the idea that certain organisms can be studied and used to gain knowledge of other organisms or as a control (ideal) for other organisms of the same species. Model organisms offer standards that serve as the authorized basis for comparison of other organisms.Rader, ''Making Mice'', p. 16 Model organisms are made standard by limiting genetic variance, creating, hopefully, this broad applicability to other organisms. The idea of the model organism first took root in the middle of the 19th century with the work of men like Charles Darwin and Gregor Mendel and their respective work on natural selection and the genetics of heredity. These early works in finding standards to compare organisms against continued into the 20th century as the first model organisms were brought into laboratories. Beginning in the early 1900s ''Drosophila'' entered the research laboratories and opened up the doors for other model organisms like Tobacco mosaic virus, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
E Coli At 10000x, Original
E, or e, is the fifth letter and the second vowel letter in the Latin alphabet, used in the modern English alphabet, the alphabets of other western European languages and others worldwide. Its name in English is ''e'' (pronounced ); plural ''ees'', ''Es'' or ''E's''. It is the most commonly used letter in many languages, including Czech, Danish, Dutch, English, French, German, Hungarian, Latin, Latvian, Norwegian, Spanish, and Swedish. History The Latin letter 'E' differs little from its source, the Greek letter epsilon, 'Ε'. This in turn comes from the Semitic letter '' hê'', which has been suggested to have started as a praying or calling human figure ('' hillul'' 'jubilation'), and was most likely based on a similar Egyptian hieroglyph that indicated a different pronunciation. In Semitic, the letter represented (and in foreign words); in Greek, ''hê'' became the letter epsilon, used to represent . The various forms of the Old Italic script and the Latin a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromosome
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity. These chromosomes display a complex three-dimensional structure, which plays a significant role in transcriptional regulation. Chromosomes are normally visible under a light microscope only during the metaphase of cell division (where all chromosomes are aligned in the center of the cell in their condensed form). Before this happens, each chromosome is duplicated ( S phase), and both copies are joined by a centromere, resulting either in an X-shaped structure (pictured above), if the centromere is located equatorially, or a two-arm structure, if the centromere is located distally. The joined copies are now called si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wendell Stanley
Wendell Meredith Stanley (16 August 1904 – 15 June 1971) was an American biochemist, virologist and Nobel laureate. Biography Stanley was born in Ridgeville, Indiana, and earned a BSc in Chemistry at Earlham College in Richmond, Indiana. He then studied at the University of Illinois, gaining an MS in science in 1927 followed by a PhD in chemistry two years later. His later accomplishments include writing the book "Chemistry: A Beautiful Thing" and being a Pulitzer Prize nominee. Research As a member of National Research Council he moved temporarily for academic work with Heinrich Wieland in Munich before he returned to the States in 1931. On return he was approved as an assistant at The Rockefeller Institute for Medical Research. He remained with the Institute until 1948, becoming an Associate Member in 1937, and a Member in 1940. In 1948, he became Professor of Biochemistry at the University of California, Berkeley and built the Virus Laboratory and a free-standing De ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ernst Ruska
Ernst August Friedrich Ruska (; 25 December 1906 – 27 May 1988) was a German physicist who won the Nobel Prize in Physics in 1986 for his work in electron optics, including the design of the first electron microscope. Life and career Ernst Ruska was born in Heidelberg, Germany. He was educated at the Technical University of Munich from 1925 to 1927 and then entered the Technical University of Berlin, where he posited that microscopes using electrons, with wavelengths 1000 times shorter than those of light, could provide a more detailed picture of an object than a microscope utilizing light, in which magnification is limited by the size of the wavelengths. In 1931, he demonstrated that a magnetic coil could act as an electron lens, and used several coils in a series to build the first electron microscope in 1933. After completing his PhD in 1933, Ruska continued to work in the field of electron optics, first at Fernseh AG in Berlin-Zehlendorf, and then from 1937 at Siemens ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TMV Virus Under Magnification
TMV may refer to: *Tobacco mosaic virus *The Mars Volta *Tindivanam railway station, Tamil Nadu, India (station code) * Trondhjems mekaniske Værksted *True market value *Thermostatic mixing valve A thermostatic mixing valve (TMV) is a valve that blends hot water with cold water to ensure constant, safe shower and bath outlet temperatures, preventing scalding. The storage of water at high temperature removes one possible breeding ground ... *Tom Merritt, Molly Wood and Veronica Belmont; hosts of the podcast Buzz Out Loud {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila Melanogaster - Side (aka)
''Drosophila'' () is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly. One species of ''Drosophila'' in particular, ''D. melanogaster'', has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and "''Drosophila''" are often used synonymously with ''D. melanogaster'' in modern biological literature. The entire genus, however, contains more than 1,500 species and is very diverse in appearance, beha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomas Hunt Morgan
Thomas Hunt Morgan (September 25, 1866 – December 4, 1945) was an American evolutionary biologist, geneticist, embryologist, and science author who won the Nobel Prize in Physiology or Medicine in 1933 for discoveries elucidating the role that the chromosome plays in heredity. Morgan received his Ph.D. from Johns Hopkins University in zoology in 1890 and researched embryology during his tenure at Bryn Mawr. Following the rediscovery of Mendelian inheritance in 1900, Morgan began to study the genetic characteristics of the fruit fly ''Drosophila melanogaster''. In his famous Fly Room at Columbia University's Schermerhorn Hall, Morgan demonstrated that genes are carried on chromosomes and are the mechanical basis of heredity. These discoveries formed the basis of the modern science of genetics. During his distinguished career, Morgan wrote 22 books and 370 scientific papers. As a result of his work, ''Drosophila'' became a major model organism in contemporary genetics. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frank Eugene Lutz
Frank Eugene Lutz (September 15, 1879 – November 27, 1943) was an American entomologist. Biography He graduated from Haverford College, Pennsylvania, in 1900 (A.B.), then from the University of Chicago in 1902 (A.M.), and then entered University College, London, England, where he was a student of Karl Pearson. He was resident investigator at the Carnegie Institution's new Station for Experimental Evolution at Cold Spring Harbor, Long Island, New York from 1904 to 1909 where he did genetic studies of Drosophila. He received a Ph.D. from the University of Chicago in 1907. His thesis was on cricket variation. In 1909, he became assistant curator of invertebrate zoology at American Museum of Natural History, New York City, becoming associate curator in 1916. He was known for his interest in the genetics of Drosophila. Dr Frank Lutz pioneered the first nature trail in the United States. An idea that spread quickly to parks across the country and the world. See Educational tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William J
William is a male given name of Germanic origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills, Willy, Willie, Bill, and Billy. A common Irish form is Liam. Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play ''Douglas''). Female forms are Willa, Willemina, Wilma and Wilhelmina. Etymology William is related to the given name ''Wilhelm'' (cf. Proto-Germanic ᚹᛁᛚᛃᚨᚺᛖᛚᛗᚨᛉ, ''*Wiljahelmaz'' > German ''Wilhelm'' and Old Norse ᚢᛁᛚᛋᛅᚼᛅᛚᛘᛅᛋ, ''Vilhjálmr''). By regular sound changes, the native, inherited English form of the name shoul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William E
William is a male given name of Germanic origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills, Willy, Willie, Bill, and Billy. A common Irish form is Liam. Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play ''Douglas''). Female forms are Willa, Willemina, Wilma and Wilhelmina. Etymology William is related to the given name ''Wilhelm'' (cf. Proto-Germanic ᚹᛁᛚᛃᚨᚺᛖᛚᛗᚨᛉ, ''*Wiljahelmaz'' > German ''Wilhelm'' and Old Norse ᚢᛁᛚᛋᛅᚼᛅᛚᛘᛅᛋ, ''Vilhjálmr''). By regular sound changes, the native, inherited English form of the name should b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles W
The F/V ''Charles W'', also known as Annie J Larsen, is a historic fishing schooner anchored in Petersburg, Alaska. At the time of its retirement in 2000, it was the oldest fishing vessel in the fishing fleet of Southeast Alaska, and the only known wooden fishing vessel in the entire state still in active service. Launched in 1907, she was first used in the halibut fisheries of Puget Sound and the Bering Sea as the ''Annie J Larsen''. In 1925 she was purchased by the Alaska Glacier Seafood Company, refitted for shrimp trawling, and renamed ''Charles W'' in honor of owner Karl Sifferman's father. The company was one of the pioneers of the local shrimp fishery, a business it began to phase out due to increasing competition in the 1970s. The ''Charles W'' was the last of the company's fleet of ships, which numbered twelve at its height. The boat was acquired in 2002 by the nonprofit Friends of the ''Charles W''. The boat was listed on the National Register of Historic Places in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly" or "pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, and othe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
