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Hildegard Lamfrom
Hildegard Lamfrom was a German-American molecular biologist/biochemist. She helped develop one of the first in-vitro translation systems, using rabbit reticulocyte lysate to study protein synthesis (a process called translation) in a cell-free context. This allowed her to make a number of contributions to the field including providing some of the first direct evidence for the existence of messenger RNA (mRNA) as a protein template, as well as the existence of polyribosomes (aka polysomes) (multiple ribosomes translating on the same mRNA). Early life and education Lamfrom was born into a Jewish family in Augsburg, Germany in 1922, the eldest of three sisters (Gertrude (Gert) Boyle and Eva). Her family fled Germany in 1937, when she was 15, and established themselves in Portland, Oregon. Her father, who had owned a shirt factory in Germany bought a small hat and cap company that the family grew into Columbia Sportswear. Her sister Gert Boyle would later run the company an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
La Jolla
La Jolla ( , ) is a hilly, seaside neighborhood within the city of San Diego, California, United States, occupying of curving coastline along the Pacific Ocean. The population reported in the 2010 census was 46,781. La Jolla is surrounded on three sides by ocean bluffs and beaches and is located north of Downtown San Diego and south of the Orange County, California, Orange County line. The climate is mild, with an average daily temperature of . La Jolla is home to many educational institutions and a variety of businesses in the areas of lodging, dining, shopping, software, finance, real estate, bioengineering, medical practice and scientific research. The University of California, San Diego (UCSD) is located in La Jolla, as are the Salk Institute for Biological Studies, Salk Institute, Scripps Institution of Oceanography (part of UCSD), Scripps Research Institute, and the headquarters of National University (California), National University (though its academic campuses are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Renin
Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that increases the volume of extracellular fluid (blood plasma, lymph and interstitial fluid) and causes arterial vasoconstriction. Thus, it increases the body's mean arterial blood pressure. Renin is not commonly referred to as a hormone, albeit it having a receptor, the (pro)renin receptor, also known as the renin receptor and prorenin receptor (see also below), as well as enzymatic activity with which it hydrolyzes angiotensinogen to angiotensin I. Biochemistry and physiology Structure The primary structure of renin precursor consists of 406 amino acids with a pre- and a pro-segment carrying 20 and 46 amino acids, respectively. Mature renin contains 340 amino acids and has a mass of 37 kDa. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sydney Brenner
Sydney Brenner (13 January 1927 – 5 April 2019) was a South African biologist. In 2002, he shared the Nobel Prize in Physiology or Medicine with H. Robert Horvitz and Sir John E. Sulston. Brenner made significant contributions to work on the genetic code, and other areas of molecular biology while working in the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge, England. He established the roundworm ''Caenorhabditis elegans'' as a model organism for the investigation of developmental biology, and founded the Molecular Sciences Institute in Berkeley, California, United States.''The Science Times Book of the Brain'' 1998. Edited by Nicholas Wade. The Lyons Press Horace Freeland Judson ''The Eighth Day of Creation'' (1979), pp. 10–11 ''Makers of the Revolution in Biology''; Penguin Books 1995, first published by Jonathan Cape, 1977; ."Sydney Brenner: A Biography" by Errol Friedberg, pub. CSHL Press October 2010, . Education and early life Br ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Francis Crick
Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical structure of the DNA molecule. Crick and Watson's paper in ''Nature'' in 1953 laid the groundwork for understanding DNA structure and functions. Together with Maurice Wilkins, they were jointly awarded the 1962 Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material". Crick was an important theoretical molecular biologist and played a crucial role in research related to revealing the helical structure of DNA. He is widely known for the use of the term " central dogma" to summarise the idea that once information is transferred from nucleic acids (DNA or RNA) to proteins, it cannot flow back to nucleic acids. In other words ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cambridge
Cambridge ( ) is a university city and the county town in Cambridgeshire, England. It is located on the River Cam approximately north of London. As of the 2021 United Kingdom census, the population of Cambridge was 145,700. Cambridge became an important trading centre during the Roman and Viking ages, and there is archaeological evidence of settlement in the area as early as the Bronze Age. The first town charters were granted in the 12th century, although modern city status was not officially conferred until 1951. The city is most famous as the home of the University of Cambridge, which was founded in 1209 and consistently ranks among the best universities in the world. The buildings of the university include King's College Chapel, Cavendish Laboratory, and the Cambridge University Library, one of the largest legal deposit libraries in the world. The city's skyline is dominated by several college buildings, along with the spire of the Our Lady and the English Martyrs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MRC Laboratory Of Molecular Biology The Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) is a research institute in Cambridge, England, involved in the revoluti |
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