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Henri François Le Dran
Henri François Le Dran (13 October 1685 – 17 October 1770) was a French surgeon. He gave lectures with the Royal Academy of Medicine in Paris, and practiced surgery at Hôpital de la Charité. He is remembered for his work with surgeon Jean-Louis Petit (1674–1750). Among his students was Swiss anatomist Albrecht von Haller (1708–1777). Le Dran made contributions in his pioneer research of cancer, and his work involving military surgery. He was among the first physicians to realize that cancer was a local affliction, and not a systemic malady. He postulated that cancer progressed in stages, and that it began as a local organic disease. He advocated surgery for cancer before the tumor was allowed to metastasize through the lymphatic system and affect other parts of the body. In 1741, Le Dran was the first to describe the phenomenon known as the Spigelian hernia. He was elected in January 1745 a Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tumor
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, which may be called a tumour or tumor.'' ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, such as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word neoplasm is from Ancient Greek 'new' and 'formation, creation'. Types A neopla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1770 Deaths
Events January– March * January 1 – The foundation of Fort George, Bombay is laid by Colonel Keating, principal engineer, on the site of the former Dongri Fort. * February 1 – Thomas Jefferson's home at Shadwell, Virginia is destroyed by fire, along with most of his books. * February 14 – Scottish explorer James Bruce arrives at Gondar, capital of Abyssinia (modern-day Ethiopia) and is received by the Emperor Tekle Haymanot II and Ras Mikael Sehul. * February 22 – Christopher Seider, an 11-year-old boy in Boston in the British Province of Massachusetts Bay, is shot and killed by a colonial official, Ebenezer Richardson. The funeral sets off anti-British protests that lead to the massacre days later. * March 5 – Boston Massacre: Eleven American men are shot (five fatally) by British troops, in an event that helps start the American Revolutionary War five years later. * March 21 – King Prithvi Narayan Shah shifts to th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1685 Births
Events January–March * January 6 – American-born British citizen Elihu Yale, for whom Yale University in the U.S. is named, completes his term as the first leader of the Madras Presidency in India, administering the colony on behalf of the East India Company, and is succeeded by William Gyfford. * January 8 – Almost 200 people are arrested in Coventry by English authorities for gathering to hear readings of the sermons of the non-conformist Protestant minister Obadiah Grew * February 4 – A treaty is signed between Brandenburg-Prussia and the indigenous chiefs at Takoradi in what is now Ghana to permit the German colonists to build a third fort on the Brandenburger Gold Coast. * February 6 – Catholic James Stuart, Duke of York, becomes King James II of England and Ireland, and King James VII of Scotland, in succession to his brother Charles II (1660–1685), King of England, Scotland, and Ireland since 1660. James II and VII reigns ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shock (circulatory)
Shock is the state of insufficient blood flow to the tissues of the body as a result of problems with the circulatory system. Initial symptoms of shock may include weakness, tachycardia, hyperventilation, sweating, anxiety, and increased thirst. This may be followed by confusion, unconsciousness, or cardiac arrest, as complications worsen. Shock is divided into four main types based on the underlying cause: hypovolemic, cardiogenic, obstructive, and distributive shock. Hypovolemic shock, also known as low volume shock, may be from bleeding, diarrhea, or vomiting. Cardiogenic shock may be due to a heart attack or cardiac contusion. Obstructive shock may be due to cardiac tamponade or a tension pneumothorax. Distributive shock may be due to sepsis, anaphylaxis, injury to the upper spinal cord, or certain overdoses. The diagnosis is generally based on a combination of symptoms, physical examination, and laboratory tests. A decreased pulse pressure ( systolic blood pre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellow Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Overview Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to :Fellows of the Royal Society, around 8,000 fellows, including eminent scientists Isaac Newton (1672), Benjamin Franklin (1756), Charles Babbage (1816), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Jagadish Chandra Bose (1920), Albert Einstein (1921), Paul Dirac (1930), Subrahmanyan Chandrasekhar (1944), Prasanta Chandra Mahalanobis (1945), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955), Satyendra Nath Bose (1958), and Francis Crick (1959). More recently, fellow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spigelian Hernia
A Spigelian hernia is the type of ventral hernia that occurs through the Spigelian aponeurosis, which is the part of the aponeurosis of the transverse abdominal muscle bounded by the linea semilunaris (or Spigelian line) laterally and the lateral edge of the rectus abdominis muscle medially. It is the protuberance of omentum, adipose tissue, or bowel in that weak space between the abdominal wall muscles, that ultimately pushes the intestines or superficial fatty tissue through a hole causing a defect. As a result, it creates the movement of an organ or a loop of intestine in the weakened body space that it is not supposed to be in. It is at this separation (aponeurosis) in the ventral abdominal region, that herniation most commonly occurs. Spigelian hernias are rare compared to other types of hernias because they do not develop under abdominal layers of fat but between fascia tissue that connects to muscle. The Spigelian hernia is generally smaller in diameter, typically measuri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lymphatic System
The lymphatic system, or lymphoid system, is an organ system in vertebrates that is part of the immune system and complementary to the circulatory system. It consists of a large network of lymphatic vessels, lymph nodes, lymphoid organs, lymphatic tissue and lymph. Lymph is a clear fluid carried by the lymphatic vessels back to the heart for re-circulation. The Latin word for lymph, , refers to the deity of fresh water, "Lympha". Unlike the circulatory system that is a closed system, the lymphatic system is open. The human circulatory system processes an average of 20 litres of blood per day through Starling equation, capillary filtration, which removes blood plasma, plasma from the blood. Roughly 17 litres of the filtered blood is reabsorbed directly into the blood vessels, while the remaining three litres are left in the interstitial fluid. One of the main functions of the lymphatic system is to provide an accessory return route to the blood for the surplus three litres. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metastasize
Metastasis is a pathogenic agent's spreading from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, are metastases (mets). It is generally distinguished from cancer invasion, which is the direct extension and penetration by cancer cells into neighboring tissues. Cancer occurs after cells are genetically altered to proliferate rapidly and indefinitely. This uncontrolled proliferation by mitosis produces a primary tumor, primary tumour heterogeneity, heterogeneic tumour. The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a Malignancy, malignant phenotype. This malignancy allows for invasion into the circulation, followed by invasion to a second site for tumorigenesis. Some cancer cells, known as circulating tumor cells (CTCs), are able to penetrate the walls of lymp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organ (anatomy)
In a multicellular organism, an organ is a collection of Tissue (biology), tissues joined in a structural unit to serve a common function. In the biological organization, hierarchy of life, an organ lies between Tissue (biology), tissue and an organ system. Tissues are formed from same type Cell (biology), cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The Gastrointestinal tract, intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system. An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma (tissue), stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerve t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgeon
In medicine, a surgeon is a medical doctor who performs surgery. Even though there are different traditions in different times and places, a modern surgeon is a licensed physician and received the same medical training as physicians before specializing in surgery. In some countries and jurisdictions, the title of 'surgeon' is restricted to maintain the integrity of the craft group in the medical profession. A specialist regarded as a legally recognized surgeon includes podiatry, dentistry, and veterinary medicine. It is estimated that surgeons perform over 300 million surgical procedures globally each year. History The first person to document a surgery was the 6th century BC Indian physician-surgeon, Sushruta. He specialized in cosmetic plastic surgery and even documented an open rhinoplasty procedure.Papel, Ira D. and Frodel, John (2008) ''Facial Plastic and Reconstructive Surgery''. Thieme Medical Pub. His Masterpiece, magnum opus ''Suśruta-saṃhitā'' is one of the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible Signs and symptoms of cancer, signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in defecation, bowel movements. While these symptoms may indicate cancer, they can also have other causes. List of cancer types, Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor Diet (nutrition), diet, sedentary lifestyle, lack of physical activity or Alcohol abuse, excessive alcohol consumption. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. infectious causes of cancer, Infection with specific viruses, bacteria and parasites is an environmental factor cau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
