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Henri François Le Dran
Henri François Le Dran (13 October 1685 – 17 October 1770) was a French surgeon. He gave lectures with the Royal Academy of Medicine in Paris, and practiced surgery at Hôpital de la Charité. He is remembered for his work with surgeon Jean-Louis Petit (1674–1750). Among his students was Swiss anatomist Albrecht von Haller (1708–1777). Le Dran made contributions in his pioneer research of cancer, and his work involving military surgery. He was among the first physicians to realize that cancer was a local affliction, and not a systemic malady. He postulated that cancer progressed in stages, and that it began as a local organic disease. He advocated surgery for cancer before the tumor was allowed to metastasize through the lymphatic system and affect other parts of the body. In 1741, Le Dran was the first to describe the phenomenon known as the Spigelian hernia A Spigelian is the type of ventral hernia where aponeurotic fascia pushes through a hole in the junction of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Henri François Le Dran
Henri François Le Dran (13 October 1685 – 17 October 1770) was a French surgeon. He gave lectures with the Royal Academy of Medicine in Paris, and practiced surgery at Hôpital de la Charité. He is remembered for his work with surgeon Jean-Louis Petit (1674–1750). Among his students was Swiss anatomist Albrecht von Haller (1708–1777). Le Dran made contributions in his pioneer research of cancer, and his work involving military surgery. He was among the first physicians to realize that cancer was a local affliction, and not a systemic malady. He postulated that cancer progressed in stages, and that it began as a local organic disease. He advocated surgery for cancer before the tumor was allowed to metastasize through the lymphatic system and affect other parts of the body. In 1741, Le Dran was the first to describe the phenomenon known as the Spigelian hernia A Spigelian is the type of ventral hernia where aponeurotic fascia pushes through a hole in the junction of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tumor
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1770 Deaths
Year 177 ( CLXXVII) was a common year starting on Tuesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Commodus and Plautius (or, less frequently, year 930 ''Ab urbe condita''). The denomination 177 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Lucius Aurelius Commodus Caesar (age 15) and Marcus Peducaeus Plautius Quintillus become Roman Consuls. * Commodus is given the title ''Augustus'', and is made co-emperor, with the same status as his father, Marcus Aurelius. * A systematic persecution of Christians begins in Rome; the followers take refuge in the catacombs. * The churches in southern Gaul are destroyed after a crowd accuses the local Christians of practicing cannibalism. * Forty-seven Christians are martyred in Lyon (Saint Blandina and Pothinus, bishop o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1685 Births
Events January–March * January 6 – American-born British citizen Elihu Yale, for whom Yale University in the U.S. is named, completes his term as the first leader of the Madras Presidency in India, administering the colony on behalf of the East India Company, and is succeeded by William Gyfford. * January 8 – Almost 200 people are arrested in Coventry by English authorities for gathering to hear readings of the sermons of the non-conformist Protestant minister Obadiah Grew * February 4 – A treaty is signed between Brandenburg-Prussia and the indigenous chiefs at Takoradi in what is now Ghana to permit the German colonists to build a third fort on the Brandenburger Gold Coast. * February 6 – Catholic James Stuart, Duke of York, becomes King James II of England and Ireland, and King James VII of Scotland, in succession to his brother Charles II (1660–1685), King of England, Scotland, and Ireland since 1660. James II and VII reigns ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shock (circulatory)
Shock is the state of insufficient blood flow to the tissues of the body as a result of problems with the circulatory system. Initial symptoms of shock may include weakness, fast heart rate, fast breathing, sweating, anxiety, and increased thirst. This may be followed by confusion, unconsciousness, or cardiac arrest, as complications worsen. Shock is divided into four main types based on the underlying cause: low volume, cardiogenic, obstructive, and distributive shock. Low volume shock, also known as hypovolemic shock, may be from bleeding, diarrhea, or vomiting. Cardiogenic shock may be due to a heart attack or cardiac contusion. Obstructive shock may be due to cardiac tamponade or a tension pneumothorax. Distributive shock may be due to sepsis, anaphylaxis, injury to the upper spinal cord, or certain overdoses. The diagnosis is generally based on a combination of symptoms, physical examination, and laboratory tests. A decreased pulse pressure (systolic blood pressure m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellow Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Fellow, Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955) and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Tim Berners-Lee (2001), Venki R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spigelian Hernia
A Spigelian is the type of ventral hernia where aponeurotic fascia pushes through a hole in the junction of the linea semilunaris and the arcuate line creating a bulge. It appears in the abdomen lower quadrant between an area of dense fibrous tissue and abdominal wall muscles causing a (Spigelian aponeurosis). It is the protuberance, of omentum, adipose tissue, or bowel in that weak space between the abdominal wall muscles, that ultimately pushes the intestines or superficial fatty tissue through a hole causing a defect. As a result, it creates the movement of an organ or a loop of intestine in the weakened body space that it is not supposed to be in. It is at this separation ( aponeurosis) in the ventral abdominal region, that herniation most commonly occurs. Spigelian hernias are rare compared to other types of hernias because they do not develop under abdominal layers of fat but between fascia tissue that connects to muscle. The Spigelian hernia is generally smaller in diamet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lymphatic System
The lymphatic system, or lymphoid system, is an organ system in vertebrates that is part of the immune system, and complementary to the circulatory system. It consists of a large network of lymphatic vessels, lymph nodes, lymphatic or lymphoid organs, and lymphoid tissues. The vessels carry a clear fluid called lymph (the Latin word ''lympha'' refers to the deity of fresh water, "Lympha") back towards the heart, for re-circulation. Unlike the circulatory system that is a closed system, the lymphatic system is open. The human circulatory system processes an average of 20 litres of blood per day through capillary filtration, which removes plasma from the blood. Roughly 17 litres of the filtered blood is reabsorbed directly into the blood vessels, while the remaining three litres are left in the interstitial fluid. One of the main functions of the lymphatic system is to provide an accessory return route to the blood for the surplus three litres. The other main function is that of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metastasize
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, are metastases (mets). It is generally distinguished from cancer invasion, which is the direct extension and penetration by cancer cells into neighboring tissues. Cancer occurs after cells are genetically altered to proliferate rapidly and indefinitely. This uncontrolled proliferation by mitosis produces a primary heterogeneic tumour. The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a malignant phenotype. This malignancy allows for invasion into the circulation, followed by invasion to a second site for tumorigenesis. Some cancer cells known as circulating tumor cells acquire the ability to penetrate the walls of lymphatic or blood vessels, after which they are able t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organ (anatomy)
In biology, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system. An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerves that innervate the parenchyma, the blood vessels that oxygenate and nourish it and carry away its metabolic wastes, and the con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgeon
In modern medicine, a surgeon is a medical professional who performs surgery. Although there are different traditions in different times and places, a modern surgeon usually is also a licensed physician or received the same medical training as physicians before specializing in surgery. There are also surgeons in podiatry, dentistry, and veterinary medicine. It is estimated that surgeons perform over 300 million surgical procedures globally each year. History The first person to document a surgery was the 6th century BC Indian physician-surgeon, Sushruta. He specialized in cosmetic plastic surgery and even documented an open rhinoplasty procedure.Ira D. Papel, John Frodel, ''Facial Plastic and Reconstructive Surgery'' His magnum opus ''Suśruta-saṃhitā'' is one of the most important surviving ancient treatises on medicine and is considered a foundational text of both Ayurveda and surgery. The treatise addresses all aspects of general medicine, but the translator G. D. Si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
