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HeLa Cell Endocytic Pathway Labeled For EGFR And Transferrin
HeLa (; also Hela or hela) is an Immortalised cell line, immortalized cell line used in scientific research. It is the oldest and most commonly used human cell line. The line is derived from cervical cancer cells taken on February 8, 1951, named after Henrietta Lacks, a 31-year-old African-American mother of five, who died of cancer on October 4, 1951. The cell line was found to be remarkably durable and prolific, which allows it to be used extensively in scientific study. The cells from Lacks's cancerous cervical tumor were taken without her knowledge or consent, which was common practice in the United States at the time. Cell biologist George Otto Gey found that they could be kept alive, and developed a cell line. Previously, cells cultured from other human cells would only survive for a few days. Cells from Lacks's tumor behaved differently. History Origin In 1951, a patient named Henrietta Lacks was admitted to the Johns Hopkins Hospital with symptoms of irregular vag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Henrietta Lacks Statue, Bristol, RHS
Henrietta may refer to: * Henrietta (given name), a feminine given name, derived from the male name Henry Places * Henrietta Island in the Arctic Ocean * Henrietta, Mauritius * Henrietta, Tasmania, a locality in Australia United States * Henrietta, Missouri * Henrietta, Johnson County, Missouri * Henrietta, New York * Henrietta, Ohio * Henrietta, Pennsylvania * Henrietta, Texas * Henrietta, West Virginia * Henrietta, Wisconsin, a county subdivision ** Henrietta (ghost town), Wisconsin, a ghost town * Henrietta Township: ** Henrietta Township, Michigan ** Henrietta Township, Hubbard County, Minnesota ** Henrietta Township, Lorain County, Ohio ** Henrietta Township, LaMoure County, North Dakota Fictional characters * Henrietta de Tristain a fictional character from the Japanese light novel/anime ''Zero no Tsukaima'' * Henrietta the coach, a fictional character of ''The Railway Series'' * Henrietta (Gunslinger), a fictional character from the Japanese manga/anime ''Gunslinge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Foundation For Infantile Paralysis
March of Dimes is a United States nonprofit organization that works to improve the health of mothers and babies. The organization was founded by President Franklin D. Roosevelt in 1938, as the National Foundation for Infantile Paralysis, to combat polio. The name "March of Dimes" was coined by Eddie Cantor. After funding Jonas Salk's polio vaccine, the organization expanded its focus to the prevention of birth defects and infant mortality. In 2005, as preterm birth emerged as the leading cause of death for children worldwide, research and prevention of premature birth became the organization's primary focus. Organization March of Dimes improves the health of mothers and babies through five programming areas: medical research, education of pregnant women, community programs, government advocacy, and support of pregnant women and mothers. The organization provides women and families with educational resources on baby health, pregnancy, preconception and new motherhood, as well a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poliomyelitis
Poliomyelitis, commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 70% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia. These symptoms usually pass within one or two weeks. A less common symptom is permanent paralysis, and possible death in extreme cases.. Years after recovery, post-polio syndrome may occur, with a slow development of muscle weakness similar to that which the person had during the initial infection. Polio occurs naturally only in humans. It is highly infectious, and is spread from person to person either through fecal-oral transmission (e.g. poor hygiene, or by ingestion of food or water contaminated by human feces), or via the oral-oral route. Those who are infected may spread the disease for up to six weeks even if no symptoms are present. The disease may be diagnosed by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polio Vaccine
Polio vaccines are vaccines used to prevent poliomyelitis (polio). Two types are used: an inactivated poliovirus given by injection (IPV) and a weakened poliovirus given by mouth (OPV). The World Health Organization (WHO) recommends all children be fully vaccinated against polio. The two vaccines have eliminated polio from most of the world, and reduced the number of cases reported each year from an estimated 350,000 in 1988 to 33 in 2018. The inactivated polio vaccines are very safe. Mild redness or pain may occur at the site of injection. Oral polio vaccines cause about three cases of vaccine-associated paralytic poliomyelitis per million doses given. This compares with 5,000 cases per million who are paralysed following a polio infection. Both types of vaccine are generally safe to give during pregnancy and in those who have HIV/AIDS but are otherwise well. However, the emergence of circulating vaccine-derived poliovirus (cVDPV), a form of the vaccine virus that has rever ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jonas Salk
Jonas Edward Salk (; born Jonas Salk; October 28, 1914June 23, 1995) was an American virologist and medical researcher who developed one of the first successful polio vaccines. He was born in New York City and attended the City College of New York and New York University School of Medicine. In 1947, Salk accepted a professorship in the School of Medicine at the University of Pittsburgh. It was there that he undertook a project to determine the number of different types of poliovirus, starting in 1948. For the next seven years, Salk devoted himself towards developing a vaccine against polio. Salk was immediately hailed as a "miracle worker" when the vaccine's success was first made public in April 1955, and chose to not patent the vaccine or seek any profit from it in order to maximize its global distribution. The National Foundation for Infantile Paralysis and the University of Pittsburgh looked into patenting the vaccine but, since Salk's techniques were not novel, their paten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rebecca Skloot
Rebecca L. Skloot (born September 19, 1972) is an American science writer who specializes in science and medicine.Jessica Teisch, "Floyd Skloot & Rebecca Skloot", in '' Bookmarks'', May/June 2010. Her first book, '' The Immortal Life of Henrietta Lacks'' (2010), was one of the best-selling new books of 2010, staying on ''The New York Times'' Bestseller list for over 6 years and eventually reaching #1. It was adapted into a movie by George C. Wolfe, which premiered on HBO on April 22, 2017, and starred Rose Byrne as Skloot, and Oprah Winfrey as Lacks's daughter Deborah. Early life and education Rebecca was born in Springfield, Illinois. She is the daughter of poet, novelist, and essayist Floyd Skloot and Betsy McCarthy, a professional knitter and pattern book author. Skloot said "in the Pacific Northwest, erroots rehalf New York Jew and half Midwestern Protestant." She received her high school diploma from Metropolitan Learning Center in Portland, Oregon. After attending Po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baltimore City Paper
''Baltimore City Paper'' was a free alternative weekly newspaper published in Baltimore, Maryland, founded in 1977 by Russ Smith and Alan Hirsch. The most recent owner was the Baltimore Sun Media Group, which purchased the paper in 2014 from Times-Shamrock Communications, which had owned the newspaper since 1987. It was distributed on Wednesdays in distinctive yellow boxes found throughout the Baltimore area. The paper folded in 2017, due to the collapse of advertising revenue income to print media. The Media Group's closure announcement happened at the same meeting immediately after recognizing ''City Paper'' staff joining the Washington-Baltimore News Guild. History Russ Smith and Alan Hirsch started the Baltimore City Paper in May 1977 while students at Johns Hopkins University. It was originally named the ''City Squeeze'', and Smith and Hirsch published it using the offices of the Johns Hopkins student newspaper. In 1978, they took the paper out of the university and sta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philip I
Philip(p) I may refer to: * Philip I of Macedon (7th century BC) * Philip I Philadelphus (between 124 and 109 BC–83 or 75 BC) * Philip the Arab (c. 204–249), Roman Emperor * Philip I of France (1052–1108) * Philip I (archbishop of Cologne) (1130–1191) * Philip I, Count of Flanders (1143–1191) * Philip I of Namur, (1175–1212) * Philip I, Count of Boulogne (1200–1235) * Philip I, Count of Savoy (1207–1285) * Philip I, Latin Emperor (1243–1283) * Philip IV of France, aka Philip I of Navarre (1268–1314) * Philip I of Piedmont, known as Philip of Savoy (1278–1334) lord of Piedmont * Philip I, Prince of Taranto (1278–1331/2) * Philip I, Count of Auvergne (1323–1346) * Philip I, Duke of Burgundy (1346–1361) * Philipp I, Count of Nassau-Weilburg (1368–1429) * Philip I, Metropolitan of Moscow (died 1473) * Philipp I, Count of Katzenelnbogen (1402–1479) * Philip I, Duke of Brabant (1404–1430) * Philipp I, Count of Hanau-Lichtenberg (1417–1480) * Philip ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Theodore Puck
Theodore Thomas Puck (September 24, 1916 – November 6, 2005) was an American geneticist born in Chicago, Illinois. He attended Chicago public schools and obtained his bachelors, masters, and doctoral degree from the University of Chicago. His PhD work was on the laws governing the impact of an electron upon an atom and his doctoral adviser was James Franck. During WW II Puck stayed at the University of Chicago. There he worked in the laboratory of Oswald H. Robertson on the study of how bacteria and viruses can spread through the air and on dust particles. After a postdoc position in the laboratory of Renato Dulbecco, Puck was recruited in 1948 to establish and chair the University of Colorado Medical School's department of biophysics. He retired from the University of Colorado Medical School in 1995 as professor emeritus, but continued to do laboratory work there until a few weeks before his death. Puck was an early pioneer of "somatic cell genetics" and single-cell plating ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is an American supplier of scientific instrumentation, reagents and consumables, and software services. Based in Waltham, Massachusetts, Thermo Fisher was formed through the merger of Thermo Electron and Fisher Scientific in 2006. Thermo Fisher Scientific has acquired other reagent, consumable, instrumentation, and service providers, including: Life Technologies Corporation (2013), Alfa Aesar (2015), Affymetrix (2016), FEI Company (2016), BD Advanced Bioprocessing (2018), and PPD (2021). As of 2017, the company had a market capitalization of $21 billion and was a Fortune 500 company. Annual revenue in 2021 was US$39.21 billion. In March 2020, Thermo Fisher Scientific received emergency use authorization from the FDA for a test for SARS-CoV-2 to help mitigate the COVID-19 pandemic. History Predecessors and merger Thermo Electron was co-founded in 1956 by George N. Hatsopoulos and Peter M Nomikos. Hatsopoulos received a PhD from MIT in me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Common Rule
The Common Rule is a 1981 rule of ethics in the United States regarding biomedical and behavioral research involving human subjects. A significant revision became effective July 2018. It governed Institutional Review Boards for oversight of human research and followed the 1975 revision of the Declaration of Helsinki; it is encapsulated in the 1991 revision to the U.S. Department of Health and Human Services Title 45 CFR 46 (Public Welfare) Subparts A, B, C and D. Subpart A. The Common Rule is the baseline standard of ethics by which any government-funded research in the US is held; nearly all U.S. academic institutions hold their researchers to these statements of rights regardless of funding. Background The Common Rule is a 1981 rule of ethics (revised in 2018) regarding biomedical and behavioral research involving human subjects in the United States. The regulations governing Institutional Review Boards for oversight of human research followed the 1975 revision of the Declara ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
