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Harry Ostrer
Harry Ostrer is a medical geneticist who investigates the genetic basis of common and rare disorders. In the diagnostic laboratory, he translates the findings of genetic discoveries into tests that can be used to identify people's risks for disease prior to occurrence, or for predicting its outcome once it has occurred. He is also known for his study, writing and lectures on the origins of the Jewish people. He is a Professor of Pathology and Genetics at Albert Einstein College of Medicine of Yeshiva University and Director of Genetic and Genomic Testing at Montefiore Medical Center. For the prior 21 years he was Professor of Pediatrics, Pathology and Medicine and Director of the Human Genetics Program at New York University School of Medicine. Education Ostrer graduated in 1972 from the Massachusetts Institute of Technology (Physics, Course 8). As an undergraduate student, he worked in the laboratory of Salvador Luria, studying the effects of the bactericidal agent Colicin K. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathology
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in card ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Color Vision
Color vision, a feature of visual perception, is an ability to perceive differences between light composed of different wavelengths (i.e., different spectral power distributions) independently of light intensity. Color perception is a part of the larger visual system and is mediated by a complex process between neurons that begins with differential stimulation of different types of photoreceptors by light entering the eye. Those photoreceptors then emit outputs that are propagated through many layers of neurons and then ultimately to the brain. Color vision is found in many animals and is mediated by similar underlying mechanisms with common types of biological molecules and a complex history of evolution in different animal taxa. In primates, color vision may have evolved under selective pressure for a variety of visual tasks including the foraging for nutritious young leaves, ripe fruit, and flowers, as well as detecting predator camouflage and emotional states in other p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Race And Genetics
Researchers have investigated the relationship between race and genetics as part of efforts to understand how biology may or may not contribute to human racial categorization. Many constructions of race are associated with phenotypical traits and geographic ancestry, and scholars like Carl Linnaeus have proposed scientific models for the organization of race since at least the 18th century. Following the discovery of Mendelian genetics and the mapping of the human genome, questions about the biology of race have often been framed in terms of genetics. A wide range of research methods have been employed to examine patterns of human variation and their relations to ancestry and racial groups, including studies of individual traits, studies of large populations and genetic clusters, and studies of genetic risk factors for disease. Research into race and genetics has also been criticized as emerging from, or contributing to, scientific racism. Some have interpreted genetic studies ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frontiers Media
Frontiers Media SA is a publisher of peer-reviewed, open access, scientific journals currently active in science, technology, and medicine. It was founded in 2007 by Kamila and Henry Markram, and has since expanded to other academic fields. Frontiers is based in Lausanne, Switzerland, with other offices in London, Madrid, Seattle and Brussels. In 2022, Frontiers employed more than 1,400 people, across 14 countries. All Frontiers journals are published under a Creative Commons Attribution License. As of 2022, Frontiers publishes over 185 academic journals, including 48 journals indexed within the Science Citation Index Expanded, and 4 journals indexed within the Social Sciences Citation Index, with a total of 51 journals ranked with an impact factor. Frontiers journals are included in the Directory of Open Access Journals (DOAJ). Frontiers is also a member of the Open Access Scholarly Publishers Association (OASPA), a participating publisher and supporter of the Initiative for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Raphael Falk (academic)
Raphael Falk (July 14, 1929 – September 15, 2019) was a German-born Israeli geneticist and historian of science. He was professor emeritus of genetics at the Hebrew University of Jerusalem in Israel. His early research was on the genetics of ''Drosophila''; from 1983 he was active in researching the history and philosophy of science, with a particular focus on genetics. Biography Falk was born in Frankfurt am Main, Germany. He was educated at the University of Stockholm, where he worked with Gert Bonnier, and the Hebrew University of Jerusalem. He subsequently completed his postdoc with H. J. Muller and Curt Stern. His former teacher, Elisabeth Goldschmidt, eventually persuaded him to switch his research focus from ''Drosophila'' genetics to the history and philosophy of genetics as it pertains to the people of Israel. He was married to psychologist and probability theorist Ruma Falk Ruma Falk ( he, רומה פלק, née Oren-Aharonovich, 1932–2020) was an Israeli psycholog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Biology (journal)
''Human Biology'' is a peer reviewed scientific journal, currently published by Wayne State University Press. The journal was established in 1929 by Raymond Pearl and is the official publication of the American Association of Anthropological Genetics. The focus of the journal is human genetics, covering topics from human population genetics, evolutionary and genetic demography and quantitative genetics. It also covers ancient DNA studies, evolutionary biological anthropology, and research exploring biological diversity expressed in terms of adaptation. The journal also publishes interdisciplinary research linking biological and cultural diversity from evidence such sources as archaeology, ethnography and cultural anthropology studies, and more. As of February 14, 2020, the journal is on Volume 90, Issue 4. The journal's current editor is Ripan S. Malhi (University of Illinois Urbana-Champaign). Publication Details Impact Factor and Other Measurements of Importance According to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catherine DeAngelis
Catherine D. DeAngelis is the first woman and the first pediatrician to become editor of the ''Journal of the American Medical Association'' (JAMA)."Catherine D. DeAngelis, MD, Is Named New JAMA Editor" Mike Mitka, JAMA. 1999;282:1609–1610."Catherine DeAngelis, M.D., M.P.H., Receives AACAP Catcher In The Rye Humanitarian Of The Year Award And Will Speak At AACAP Annual Meeting" Medical News Today, October 24, 2008. She has also edited several additional medical journals. Before assuming the editor's position ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eran Elhaik
Eran Elhaik (born 1980) is an Israeli-American geneticist and bioinformatician, and an associate professor of bioinformatics at Lund University in Sweden. His research uses computational, statistical, epidemiological and mathematical approaches to fields such as complex disorders, population genetics, personalised medicine, molecular evolution, genomics, paleogenomics and epigenetics. Career After completing undergraduate studies in Israel, he obtained a PhD in molecular evolution under the supervision of Dan Graur at the University of Houston in 2009, followed by postdoctoral research fellowships at the Johns Hopkins University School of Medicine and School of Public Health. In 2011 the Genographic Project, after concerns emerged about the retention of private genetic data of individuals in surveyed populations, hired Elhaik and asked him to design a method that would enable analysts to extract only historical information from the accumulating genomic evidence of population ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Forward
''The Forward'' ( yi, פֿאָרווערטס, Forverts), formerly known as ''The Jewish Daily Forward'', is an American news media organization for a Jewish American audience. Founded in 1897 as a Yiddish-language daily socialist newspaper, ''The New York Times'' reported that Seth Lipsky "started an English-language offshoot of the Yiddish-language newspaper" as a weekly newspaper in 1990. In the 21st century ''The Forward'' is a digital publication with online reporting. In 2016, the publication of the Yiddish version changed its print format from a biweekly newspaper to a monthly magazine; the English weekly paper followed suit in 2017. Those magazines were published until 2019. ''The Forward''s perspective on world and national news and its reporting on the Jewish perspective on modern United States have made it one of the most influential American Jewish publications. It is published by an independent nonprofit association. It has a politically progressive editorial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Opsin
Animal opsins are G-protein-coupled receptors and a group of proteins made light-sensitive via a chromophore, typically retinal. When bound to retinal, opsins become Retinylidene proteins, but are usually still called opsins regardless. Most prominently, they are found in photoreceptor cells of the retina. Five classical groups of opsins are involved in vision, mediating the conversion of a photon of light into an electrochemical signal, the first step in the visual transduction cascade. Another opsin found in the mammalian retina, melanopsin, is involved in circadian rhythms and pupillary reflex but not in vision. Humans have in total nine opsins. Beside vision and light perception, opsins may also sense temperature, sound, or chemicals. Structure and function Animal opsins detect light and are the molecules that allow us to see. Opsins are G-protein-coupled receptors (GPCRs), which are chemoreceptors and have seven transmembrane domains forming a binding pocket for a ligand ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemoglobin E
Hemoglobin E (HbE) is an abnormal hemoglobin with a single point mutation in the β chain. At position 26 there is a change in the amino acid, from glutamic acid to lysine (E26K). Hemoglobin E is very common among people of Southeast Asian, Northeast Indian, Sri Lankan and Bangladeshi descent. The βE mutation affects β-gene expression creating an alternate splicing site in the mRNA at codons 25-27 of the β-globin gene. Through this mechanism, there is a mild deficiency in normal β mRNA and production of small amounts of anomalous β mRNA. The reduced synthesis of β chain may cause β-thalassemia. Also, this hemoglobin variant has a weak union between α- and β-globin, causing instability when there is a high amount of oxidant. HbE can be detected on electrophoresis. Hemoglobin E disease (EE) Hemoglobin E disease results when the offspring inherits the gene for HbE from both parents. At birth, babies homozygous for the hemoglobin E allele do not present symptoms because they ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Khmer People
The Khmer people ( km, ជនជាតិខ្មែរ, ) are a Southeast Asian ethnic group native to Cambodia. They comprise over 90% of Cambodia's population of 17 million.Cambodia CIA World FactBook. They speak the , which is part of the larger Austroasiatic-language family found in parts of (including , [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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