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Hanah Margalit
Hanah Margalit is a Professor in the faculty of medicine at the Hebrew University of Jerusalem. Her research combines bioinformatics, computational biology and systems biology, specifically in the fields of gene regulation in bacteria and eukaryotes. Education Margalit earned her B.Sc degree (in Mathematics and Biology, 1974) and MSc degree (in Genetics, with distinction, 1977) from the Hebrew University of Jerusalem. In 1985, she completed her PhD in computational molecular biology, under the supervision of Norman Grover, the Hebrew University of Jerusalem. Career and research Margalit completed postdoctoral research at the National Institutes of Health (NIH) in the laboratory of mathematical biology under the supervision of Charles DeLisi, where she developed the first computational algorithm to predict antigenic peptides recognized by immune cells. In 1989, she returned to Israel and established her independent research group at the Faculty of Medicine, the Hebrew University ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mathematical Biology
Mathematical and theoretical biology, or biomathematics, is a branch of biology which employs theoretical analysis, mathematical models and abstractions of the living organisms to investigate the principles that govern the structure, development and behavior of the systems, as opposed to experimental biology which deals with the conduction of experiments to prove and validate the scientific theories. The field is sometimes called mathematical biology or biomathematics to stress the mathematical side, or theoretical biology to stress the biological side. Theoretical biology focuses more on the development of theoretical principles for biology while mathematical biology focuses on the use of mathematical tools to study biological systems, even though the two terms are sometimes interchanged. Mathematical biology aims at the mathematical representation and modeling of biological processes, using techniques and tools of applied mathematics. It can be useful in both theoretical and prac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Israeli Bioinformaticians
Israeli may refer to: * Something of, from, or related to the State of Israel * Israelis, citizens or permanent residents of the State of Israel * Modern Hebrew, a language * ''Israeli'' (newspaper), published from 2006 to 2008 * Guni Israeli (born 1984), Israeli basketball player See also * Israelites, the ancient people of the Land of Israel * List of Israelis Israelis ( he, ישראלים ''Yiśraʾelim'') are the citizens or permanent residents of the State of Israel, a multiethnic state populated by people of different ethnic backgrounds. The largest ethnic groups in Israel are Jews (75%), foll ... {{disambiguation Language and nationality disambiguation pages ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Society For Computational Biology
The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Molecular Biology (ISMB) conference and has grown to become a larger society working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide. In addition to ISMB, the society also organizes a growing number of smaller, more regionally or topically focused conferences and presents a number of annual scientific achievement awards, including the Overton Prize and the ISCB Senior Scientist Awards. Overview Society membership reflects commitment toward the advancement of computational biology. The ISCB is an international non-profit organization whose members come from the global bioinformatics and computational biology communities. The ISCB serves its global membership by providing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michael Landau
Michael Christopher Landau (born June 1, 1958) is an American musician, audio engineer, and record producer. He is a session musician and guitarist who has played on many albums since the early 1980s with Boz Scaggs, Minoru Niihara, Joni Mitchell, Rod Stewart, Seal, Michael Jackson, James Taylor, Helen Watson, Luis Miguel, Richard Marx, Steve Perry, Pink Floyd, Phil Collins on " Two Hearts" and "Loco in Acapulco", Roger Daltrey, Stevie Nicks, Glenn Frey, Eros Ramazzotti, Whitney Houston, and Miles Davis. Landau, along with fellow session guitarists Dean Parks, Steve Lukather, Michael Thompson and Dann Huff, played on many of the major label releases recorded in Los Angeles from the 1980s–1990s. He has released music with several record labels, including Ulftone Music and Tone Center Records, a member of Shrapnel Label Group. In addition to his session work, Landau has led several bands, including Raging Honkies and Burning Water. In the early 1980s, he was also in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MicroRNA
MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. Found in plants, animals and some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary sequences in mRNA molecules, then gene silence said mRNA molecules by one or more of the following processes: (1) cleavage of mRNA strand into two pieces, (2) destabilization of mRNA by shortening its poly(A) tail, or (3) translation of mRNA into proteins. This last method of gene silencing is the least efficient of the three, and requires the aid of ribosomes. miRNAs resemble the small interfering RNAs (siRNAs) of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts that fold back on themselves to form short hairpins, whereas siRNAs derive from longer regions of double-stranded RNA. The human genome may encode over 1900 miRNAs, although more recent analysis suggests that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ofer Biham
Ofer Biham ( he, עופר ביהם) is a faculty member at The Racah Institute of Physics of the Hebrew University of Jerusalem in Israel. Biham received his Ph.D. for research on quasiperiodicity, quasiperiodic systems at the Weizmann Institute of Science in 1988, under the supervision of David Mukamel. In later years, Biham was involved in the development of methods for the calculation of unstable periodic orbits in chaotic systems, models for efficient simulations of traffic flow and quantum computation. The focus of Biham's current research is on the development of computational methodologies for the simulation of stochastic processes in interstellar chemistry and in genetic networks. Biham is known for the Biham–Middleton–Levine traffic model which he formulated with A. Alan Middleton and Dov Levine in 1992. It is possibly the simplest model containing phase transitions and self-organization. His doctoral students include Daniel Lidar. Bibliography * * * * Referenc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uri Alon
Uri Alon (Hebrew: אורי אלון; born 1969) is a Professor and Systems Biologist at the Weizmann Institute of Science. His highly cited research investigates gene expression, network motifs and the design principles of biological networks in ''Escherichia coli'' and other organisms using both computational biology and traditional experimental wet laboratory techniques. Education Alon earned his bachelor's and master's degrees from the Hebrew University of Jerusalem and his Ph.D. in Theoretical Physics from the Weizmann Institute of Science. Career After having his interest in biology sparked, Alon headed to Princeton University for his postdoctoral work in experimental biology. He returned to the Weizmann Institute as a professor. Alon features in several popular videos on YouTube such as ''Sunday at the Lab'' (with Michael Elowitz) and ''How to Give a Good Talk''. As of 2011, he is the author of the most highly bookmarked scientific paper on CiteULike ''How To Choose ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein-DNA Interaction
DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. Sequence-specific DNA-binding proteins generally interact with the major groove of B-DNA, because it exposes more functional groups that identify a base pair. However, there are some known minor groove DNA-binding ligands such as netropsin, distamycin, Hoechst 33258, pentamidine, DAPI and others. Examples DNA-binding proteins include transcription factors which modulate the process of transcription, various polymerases, nucleases which cleave DNA molecules, and histones which are involved in chromosome packaging and transcription in the cell nucleus. DNA-binding proteins can incorporate such domains as the zinc finger, the helix-turn-helix, and the leucine zipper (among many others) that facilitate binding to nucleic acid. There are also more unusual examples such as transcription activator like effectors. Non-specific DNA-protein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein–protein Interaction
Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by interactions that include electrostatic forces, hydrogen bonding and the hydrophobic effect. Many are physical contacts with molecular associations between chains that occur in a cell or in a living organism in a specific biomolecular context. Proteins rarely act alone as their functions tend to be regulated. Many molecular processes within a cell are carried out by molecular machines that are built from numerous protein components organized by their PPIs. These physiological interactions make up the so-called interactomics of the organism, while aberrant PPIs are the basis of multiple aggregation-related diseases, such as Creutzfeldt–Jakob and Alzheimer's diseases. PPIs have been studied with many methods and from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal trans ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
