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Hagan Bayley
John Hagan Pryce Bayley FRS (born 13 February 1951) is a British scientist, who holds the position of Professor of Chemical Biology at the University of Oxford. Life and education Bayley was educated at The King's School, Chester, Balliol College, Oxford and Harvard University, where he was awarded a PhD in 1979. Originally from Wales, spent much of his early career between the United Kingdom and the United States. Research Bayley's research is largely based on the study and engineering of transmembrane pore-forming proteins, as well as interests in chemical signal transduction and biomolecular materials. He is the co-founder of Oxford Nanopore Technologies Ltd. Bayley's research includes work on the pore-forming protein alpha haemolysin engineered for sensing has been highly cited. Career Following his PhD, Bayley completed postdoctoral research at Massachusetts Institute of Technology. He previously held appointments at Columbia University, University of Massachusetts Med ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haemolysin
Hemolysins or haemolysins are lipids and proteins that cause lysis of red blood cells by disrupting the cell membrane. Although the lytic activity of some microbe-derived hemolysins on red blood cells may be of great importance for nutrient acquisition, many hemolysins produced by pathogens do not cause significant destruction of red blood cells during infection. However, hemolysins are often capable of lysing red blood cells ''in vitro''. While most hemolysins are protein compounds, some are lipid biosurfactants. Properties Many bacteria produce hemolysins that can be detected in the laboratory. It is now believed that many clinically relevant fungi also produce hemolysins. Hemolysins can be identified by their ability to lyse red blood cells ''in vitro''. Not only are the erythrocytes affected by hemolysins, but there are also some effects among other blood cells, such as leucocytes (white blood cells). ''Escherichia coli'' hemolysin is potentially cytotoxic to monocytes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
