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HIstome
HIstome is a database that provides information about human histone proteins, their sites of modifications, variants and modifying enzymes, and diseases linked to histone modifications. Update HISTome2 is a updated version of the HIstome database released in 2020. See also * Histone In biology, histones are highly basic proteins abundant in lysine and arginine residues that are found in eukaryotic cell nuclei. They act as spools around which DNA winds to create structural units called nucleosomes. Nucleosomes in turn a ... References External links * http://www.iiserpune.ac.in/~coee/histome/ Biological databases Epigenetics {{Biodatabase-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Database
In computing, a database is an organized collection of data stored and accessed electronically. Small databases can be stored on a file system, while large databases are hosted on computer clusters or cloud storage. The design of databases spans formal techniques and practical considerations, including data modeling, efficient data representation and storage, query languages, security and privacy of sensitive data, and distributed computing issues, including supporting concurrent access and fault tolerance. A database management system (DBMS) is the software that interacts with end users, applications, and the database itself to capture and analyze the data. The DBMS software additionally encompasses the core facilities provided to administer the database. The sum total of the database, the DBMS and the associated applications can be referred to as a database system. Often the term "database" is also used loosely to refer to any of the DBMS, the database system or an appli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histone
In biology, histones are highly basic proteins abundant in lysine and arginine residues that are found in eukaryotic cell nuclei. They act as spools around which DNA winds to create structural units called nucleosomes. Nucleosomes in turn are wrapped into 30-nanometer fibers that form tightly packed chromatin. Histones prevent DNA from becoming tangled and protect it from DNA damage. In addition, histones play important roles in gene regulation and DNA replication. Without histones, unwound DNA in chromosomes would be very long. For example, each human cell has about 1.8 meters of DNA if completely stretched out; however, when wound about histones, this length is reduced to about 90 micrometers (0.09 mm) of 30 nm diameter chromatin fibers. There are five families of histones which are designated H1/H5 (linker histones), H2, H3, and H4 (core histones). The nucleosome core is formed of two H2A-H2B dimers and a H3-H4 tetramer. The tight wrapping of DNA around histones ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indian Institute Of Science Education And Research, Pune
Indian Institute of Science Education and Research, Pune (IISER Pune) is an autonomous public university established in 2006. It is one of the seven Indian Institutes of Science Education and Research, and was one of the first IISERs to be established along with IISER Kolkata. It is located in the city of Pune, India. Campus The construction of the final campus was completed in 2012. The campus is of 98 acres. Academics Academic programmes IISER Pune offers integrated masters programmes (BS-MS), an integrated doctoral programme (Int. PhD) and a doctoral programme (PhD). Admission to the master's degree is through the IISER joint admission process which provides three channels for admission: Kishore Vaigyanik Protsahan Yojana, Joint Entrance Examination – Advanced and state and central boards candidates, which require an additional IISER Aptitude Test. Admission to the various PhD programmes is either with a master's degree in science or with a bachelor's degree, fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tata Memorial Centre
The Tata Memorial Hospital is situated in Parel, Mumbai, in India. Also popularly known as TMH. It is a specialist cancer treatment and research centre, closely associated with the Advanced Centre for Treatment, Research and Education in Cancer (ACTREC). The centre is the national comprehensive cancer centre for the prevention, treatment, education and research in cancer and is recognized as one of the leading cancer centres in this part of the world. It is an autonomous body funded and controlled by Department of Atomic Energy, Government of India which also oversees the administration of institute since 1962. The Tata Memorial Hospital was initially commissioned by the Sir Dorabji Tata Trust on 28 February 1941 as a center with enduring value and a mission for concern for the Indian people. Current Director of the hospital is Dr. Rajendra A Badwe, who took over from for director Dr. K. A. Dinshaw. History The Tata Memorial Hospital was founded by the Sir Dorabji Tata Trust ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Databases
Biological databases are libraries of biological sciences, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis. They contain information from research areas including genomics, proteomics, metabolomics, microarray gene expression, and phylogenetics. Information contained in biological databases includes gene function, structure, localization (both cellular and chromosomal), clinical effects of mutations as well as similarities of biological sequences and structures. Biological databases can be classified by the kind of data they collect (see below). Broadly, there are molecular databases (for sequences, molecules, etc.), functional databases (for physiology, enzyme activities, phenotypes, ecology etc), taxonomic databases (for species and other taxonomic ranks), images and other media, or specimens (for museum collections etc.) Databases are important tools in assisting scientists to analyze and explain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
