Golden Poison Frog
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Golden Poison Frog
The golden poison frog (''Phyllobates terribilis''), also known as the golden dart frog or golden poison arrow frog, is a poison dart frog endemic to the rainforests of Colombia. The golden poison frog has become endangered due to habitat destruction within its naturally limited range. Despite its small size, this frog is likely the most poisonous animal on the planet. Taxonomy and etymology The golden poison frog was described as ''Phyllobates terribilis'' in 1978 by herpetologists Charles W. Myers and Borys Malkin as well as biochemist John W. Daly; the species name ''terribilis'' is a reference to the deadly toxins present in the skin secretions of this species. Myers' research was based on hundreds of specimens collected on an expedition to the Quebrada Guangui and La Brea regions of the Colombian rainforest, and a breeding colony of 18 frogs established at the American Museum of Natural History. Distribution and habitat The golden poison frog is endemic to humid forests ...
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John William Daly
John William Daly (June 8, 1933 – March 5, 2008) was an American biochemist who performed research for nearly 50 years at the National Institutes of Health in Bethesda, Maryland. A primary focus of his research included the discovery, structure elucidation, synthesis, and pharmacology of alkaloid Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar ...s and other biologically active natural products. He was the world's leading authority in amphibian alkaloids and an expert in many areas of natural products. Daly was a prolific writer, producing around 700 papers, including books and chapters. In 1997 he was elected to the U.S. National Academy of Sciences. References 1933 births 2008 deaths Scientists from Portland, Oregon Deaths from pancreatic cancer American biochemists ...
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Termite
Termites are small insects that live in colonies and have distinct castes (eusocial) and feed on wood or other dead plant matter. Termites comprise the infraorder Isoptera, or alternatively the epifamily Termitoidae, within the order Blattodea (along with cockroaches). Termites were once classified in a separate order from cockroaches, but recent phylogenetic studies indicate that they evolved from cockroaches, as they are deeply nested within the group, and the sister group to wood eating cockroaches of the genus ''Cryptocercus''. Previous estimates suggested the divergence took place during the Jurassic or Triassic. More recent estimates suggest that they have an origin during the Late Jurassic, with the first fossil records in the Early Cretaceous. About 3,106 species are currently described, with a few hundred more left to be described. Although these insects are often called "white ants", they are not ants, and are not closely related to ants. Like ants and some bees a ...
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Batrachotoxin Skeletal
Batrachotoxin (BTX) is an extremely potent cardio- and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. The name is from the Greek word grc, βάτραχος, bátrachos, frog, label=none. Structurally-related chemical compounds are often referred to collectively as batrachotoxins. It is an extremely poisonous alkaloid. In certain frogs, this alkaloid is present mostly on the skin. Such frogs are among those used for poisoning darts. Batrachotoxin binds to and irreversibly opens the sodium channels of nerve cells and prevents them from closing, resulting in paralysis and death. No antidote is known. History Batrachotoxin was discovered by Fritz Märki and Bernhard Witkop, at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Maryland, U.S.A. Märki and Witkop separated the potent toxic alkaloids fraction from ''Phyllobates bicolor'' and determined its chemical properties in 1963. They isol ...
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Sodium Channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's membrane. They belong to the superfamily of cation channels and can be classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change ("voltage-gated", "voltage-sensitive", or "voltage-dependent" sodium channel; also called "VGSCs" or "Nav channel") or a binding of a substance (a ligand) to the channel (ligand-gated sodium channels). In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials. These channels go through three different states called resting, active and inactive states. Even though the resting and inactive states would not allow the ions to flow through the channels the difference exists with respect to their structural conformation. Selectivity Sodium channels are highly selective for the transport of ions across cell membr ...
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Melyridae
Melyridae (common name: soft-winged flower beetles) are a family of beetles of the superfamily Cleroidea. Description Most are elongate-oval, soft-bodied beetles 10 mm long or less. Many are brightly patterned in black and brown, yellow, or red. Some melyrids ( Malachiinae) have peculiar orange structures along the sides of the abdomen, which may be everted and saclike or withdrawn into the body and inconspicuous. Some melyrids have the two basal antennomeres greatly enlarged. Most adults and larvae are predaceous, but many are common on flowers. The most common North American species belong to the genus ''Collops'' ( Malachiinae); ''C. quadrimaculatus'' is reddish, with two bluish black spots on each elytron. Four New Guinean species of ''Choresine'' (the more abundant '' C. pulchra'', the less abundant '' C. semiopaca'' and the two infrequent '' C. rugiceps'' and '' C. sp. A'', the latter as yet unnamed) have been found to contain batrachotoxins, which may account f ...
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Choresine
''Choresine'' is a genus of beetles that belong to the Melyridae family. This genus of beetle is known to have high levels of batrachotoxins and is believed to be a possible toxin source for Pitohui and Blue-capped ifrit birds in New Guinea. Collections from Herowana in the Eastern Highlands Province that tested positive for batrachotoxins included the more abundant '' C. pulchra'', the less abundant '' C. semiopaca'' and the two infrequent '' C. rugiceps'' and '' C. sp. A'', the latter as yet unnamed. The locals advise against allowing these beetles to touch the eyes or sweaty face as a severe burning sensation can result. These species are all described as having metallic blue-violaceous elytra and a yellow and blackish pronotum. The name "nanisani" is used by villagers in Herowana equally for this group of insects, the numbing, tingling, burning sensation they cause and the Blue-capped ifrit. The hypothesis that ''Phyllobates'' frogs in South America obtain batrachotoxins fro ...
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Papua New Guinea
Papua New Guinea (abbreviated PNG; , ; tpi, Papua Niugini; ho, Papua Niu Gini), officially the Independent State of Papua New Guinea ( tpi, Independen Stet bilong Papua Niugini; ho, Independen Stet bilong Papua Niu Gini), is a country in Oceania that comprises the eastern half of the island of New Guinea and its offshore islands in Melanesia (a region of the southwestern Pacific Ocean north of Australia). Its capital, located along its southeastern coast, is Port Moresby. The country is the world's third largest island country, with an area of . At the national level, after being ruled by three external powers since 1884, including nearly 60 years of Australian administration starting during World War I, Papua New Guinea established its sovereignty in 1975. It became an independent Commonwealth realm in 1975 with Elizabeth II as its queen. It also became a member of the Commonwealth of Nations in its own right. There are 839 known languages of Papua New Guinea, one of ...
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Toxic Bird
Toxic birds are birds that use toxins to defend themselves from predators. No species of bird is known to actively inject or produce venom, but the discovered toxic birds are known to be poisonous to touch and eat. These birds usually sequester poison from animals and plants they feed on, especially poisonous insects. Birds with known toxic traits include the pitohui and ifrita birds from Papua New Guinea, the European quail, the spur-winged goose, hoopoes, the bronzewing pigeon, and the red warbler, among others. The pitohui, the ifrita, and the rufous or little shrikethrush all sequester batrachotoxin in their skin and feathers. The African spur-winged goose is toxic to eat as it sequesters poison in its tissues, from the blister beetles that it feeds on. European quail are also known to be toxic and are able to cause coturnism at certain stages in their migrations. Initial research The first research done on toxic birds was published in 1992 by Dumbacher ''et al.'', which ...
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Phyllobates
''Phyllobates'' is a genus of poison dart frogs native to Central and South America, from Nicaragua to Colombia. There are 3 different Colombian species of ''Phyllobates'', considered highly toxic species due to the poison they contain in the wild. ''Phyllobates'' contains the most poisonous species of frog, the golden poison frog (''P. terribilis''). They are typical of the poison dart frogs, in that all species have bright warning coloration (aposematism), and have varying degrees of toxicity. Only species of ''Phyllobates'' are used by natives of South American tribes as sources of poison for their hunting darts. The most toxic of the many poisonous alkaloids these frogs contain (in glands in their skin) is batrachotoxin, alongside a wide variety of other toxic compounds. Some populations of ''Phyllobates lugubris'' in Central America are not known to be toxic. Taxonomy ''Phyllobates'' (Ancient Greek for "leaf climber") used to contain many of the species which are now withi ...
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Batrachotoxin
Batrachotoxin (BTX) is an extremely potent cardio- and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. The name is from the Greek word grc, βάτραχος, bátrachos, frog, label=none. Structurally-related chemical compounds are often referred to collectively as batrachotoxins. It is an extremely poisonous alkaloid. In certain frogs, this alkaloid is present mostly on the skin. Such frogs are among those used for poisoning darts. Batrachotoxin binds to and irreversibly opens the sodium channels of nerve cells and prevents them from closing, resulting in paralysis and death. No antidote is known. History Batrachotoxin was discovered by Fritz Märki and Bernhard Witkop, at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Maryland, U.S.A. Märki and Witkop separated the potent toxic alkaloids fraction from ''Phyllobates bicolor'' and determined its chemical properties in 1963. They isolat ...
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Erythrolamprus Epinephalus
''Erythrolamprus epinephalus'' is a species of snake in the Colubridae family. It is endemic to South America. The snake, which was described by Edward Drinker Cope in 1862, is notable for its apparent immunity to the toxic skin of the Golden Golden means made of, or relating to gold. Golden may also refer to: Places United Kingdom *Golden, in the parish of Probus, Cornwall * Golden Cap, Dorset *Golden Square, Soho, London *Golden Valley, a valley on the River Frome in Gloucestershi ... poison dart frog, which it preys upon. :''Common name: Fire-bellied Snake'' References Reptiles described in 1862 Erythrolamprus Taxobox binomials not recognized by IUCN {{Colubrids-stub ...
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Bromeliad
The Bromeliaceae (the bromeliads) are a family of monocot flowering plants of about 80 genera and 3700 known species, native mainly to the tropical Americas, with several species found in the American subtropics and one in tropical west Africa, ''Pitcairnia feliciana''. It is among the basal families within the Poales and is the only family within the order that has septal nectaries and inferior ovaries.Judd, Walter S. Plant systematics a phylogenetic approach. 3rd ed. Sunderland, MA: Sinauer Associates, Inc., 2007. These inferior ovaries characterize the Bromelioideae, a subfamily of the Bromeliaceae. The family includes both epiphytes, such as Spanish moss (''Tillandsia usneoides''), and terrestrial species, such as the pineapple (''Ananas comosus''). Many bromeliads are able to store water in a structure formed by their tightly overlapping leaf bases. However, the family is diverse enough to include the tank bromeliads, grey-leaved epiphyte ''Tillandsia'' species that gath ...
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