Gertrude Maud Robinson
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Gertrude Maud Robinson
Gertrude Maud Robinson (formerly Walsh) was an influential organic chemist most famous for her work on plant pigments; the Piloty-Robinson Pyrrole Synthesis, which is named for her; her syntheses of fatty acids; and her synthesis of δ-hexenolactone,Medawar, P.B.; Robinson, G.M.; Robinson, R. A Synthetic Differential Growth Inhibitor. ''Nature'', 1943, ''151'', 195. the first synthetic molecule with the character of penicillin.Dunstan, A.E.; Woodhead, D.W.; Simonsen, J.L. Obituary notices. ''J. Chem. Soc. '', 1954, 2664–2668. Biography Robinson was born on 6 February 1886 in Winsford, Cheshire and died of a heart attack on 1 March 1954. After attending Verdin Secondary School, she was granted her B. Sc. in 1907 and M. Sc. in 1908 from Owens College. She then researched at the University of Manchester under Chaim Weizmann, who later became the first president of Israel, and taught chemistry at the Manchester High School for Girls. In 1912 she married Robert Robinson, who ...
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Winsford
Winsford is a town and civil parishes in England, civil parish in the unitary authority of Cheshire West and Chester and the ceremonial county of Cheshire, England, on the River Weaver south of Northwich and west of Middlewich. It grew around the Salt mine, salt mining industry after the river was canalised in the 18th century, allowing freight to be conveyed northwards to the Port of Runcorn on the River Mersey. Winsford is split into three areas: Over, Cheshire, Over on the western side of the River Weaver, Wharton on the eastern side, and Swanlow and Dene. History Early origins Winsford consists of three ancient parishes, St Chads, Over and Wharton, which in the 19th century were combined. The name “Winsford” is of uncertain origin but is thought to derive from Wain’s or Wynne’s and Ford (Mr Wain's crossing point of the river Weaver). The Norman Earl of Chester, Earls of Chester had a hunting lodge or summer palace at Darnhall in Over, Cheshire, Over parish. The ...
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Azoxy
In chemistry, azoxy compounds are a group of chemical compounds sharing a common functional group with the general structure . They are considered N-oxides of azo compounds. Azoxy compounds are 1,3-dipoles. They undergo 1,3-dipolar cycloaddition with double bonds. Preparation Most azoxy-containing compounds have aryl substituents. They are typically prepared by reduction of nitrocompounds, such as the reduction of nitrobenzene with arsenous oxide to azoxybenzene. Such reactions are proposed to proceed via the intermediacy of the hydroxylamine and nitroso compounds, e.g. phenylhydroxylamine and nitrosobenzene (Ph = phenyl In organic chemistry, the phenyl group, or phenyl ring, is a cyclic group of atoms with the formula C6 H5, and is often represented by the symbol Ph. Phenyl group is closely related to benzene and can be viewed as a benzene ring, minus a hydroge ..., ): :PhNHOH + PhNO -> PhN(O)NPh + H2O Safety Alkyl azoxy compounds, e.g. azoxymethane are suspec ...
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Miscibility
Miscibility () is the property of two substances to mix in all proportions (that is, to fully dissolve in each other at any concentration), forming a homogeneous mixture (a solution). The term is most often applied to liquids but also applies to solids and gases. For example, water and ethanol are miscible because they mix in all proportions. By contrast, substances are said to be immiscible if there are certain proportions in which the mixture does not form a solution. For one example, oil is not soluble in water, so these two solvents are immiscible. As another example, butanone (methyl ethyl ketone) is significantly soluble in water, but these two solvents are also immiscible because in some proportions the mixture will separate into two phases. Organic compounds In organic compounds, the weight percent of hydrocarbon chain often determines the compound's miscibility with water. For example, among the alcohols, ethanol has two carbon atoms and is miscible with water ...
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Flavonols
Flavonols are a class of flavonoids that have the 3-hydroxyflavone backbone (IUPAC name : 3-hydroxy-2-phenylchromen-4-one). Their diversity stems from the different positions of the phenolic -OH groups. They are distinct from flavanols (with "a") such as catechin, another class of flavonoids. Flavonols are present in a wide variety of fruits and vegetables. In Western populations, estimated daily intake is in the range of 20–50 mg per day for flavonols. Individual intake varies depending on the type of diet consumed. The phenomenon of dual fluorescence (due to excited state intramolecular proton transfer or ESIPT) is induced by tautomerism of flavonols (and glucosides) and could contribute to plant UV protection and flower colour. Besides being a subclass of flavonoids, flavonols are suggested by a study of cranberry juice to play a role along with proanthocyanidins, in the juice's ability to block bacterial adhesion, demonstrated by the compressing the fimbria of ...
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Copigmentation
Copigmentation is a phenomenon where pigmentation due to anthocyanidins is reinforced by the presence of other colorless flavonoids known as cofactors or “copigments”. This occurs by the formation of a non-covalently-linked complex. Examples ;Flowers An example is the bluish purple flowers of the Japanese garden iris (''Iris ensata''). The characteristic floral jade coloration of ''Strongylodon macrobotrys'' has been shown to be an example of copigmentation, a result of the presence of malvin (the anthocyanin) and saponarin (a flavone glucoside) in the ratio 1:9.Greenish blue flower colour of Strongylodon macrobotrys. Kosaku Takeda, Aki Fujii, Yohko Senda and Tsukasa Iwashina, Biochemical Systematics and Ecology, Volume 38, Issue 4, August 2010, Pages 630–633, ;Berries It is a phenomenon observed in the berry color of the porcelain berry (''Ampelopsis glandulosa''). ;Food Part of the color of red wine can be due to the copigmentation phenomenon. Copigmentation is only im ...
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British Science Association
The British Science Association (BSA) is a Charitable organization, charity and learned society founded in 1831 to aid in the promotion and development of science. Until 2009 it was known as the British Association for the Advancement of Science (BA). The current Chief Executive is Katherine Mathieson. The BSA's mission is to get more people engaged in the field of science by coordinating, delivering, and overseeing different projects that are suited to achieve these goals. The BSA "envisions a society in which a diverse group of people can learn and apply the sciences in which they learn." and is managed by a professional staff located at their Head Office in the Wellcome Wolfson Building. The BSA offers a wide variety of activities and events that both recognize and encourage people to be involved in science. These include the British Science Festival, British Science Week, the CREST Awards, Huxley Summit, Media Fellowships Scheme, along with regional and local events. Histor ...
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Honorary Degree
An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or '' ad honorem '' ("to the honour"). The degree is typically a doctorate or, less commonly, a master's degree, and may be awarded to someone who has no prior connection with the academic institution or no previous postsecondary education. An example of identifying a recipient of this award is as follows: Doctorate in Business Administration (''Hon. Causa''). The degree is often conferred as a way of honouring a distinguished visitor's contributions to a specific field or to society in general. It is sometimes recommended that such degrees be listed in one's curriculum vitae (CV) as an award, and not in the education section. With regard to the use of this honorific, the policies of institutions of higher education generally ask that recipient ...
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Antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antise ...
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Leucoanthocyanidin
Leucoanthocyanidin (flavan-3,4-diols) are colorless chemical compounds related to anthocyanidins and anthocyanins. Leucoanthocyanins can be found in ''Anadenanthera peregrina'' and in several species of ''Nepenthes'' including '' N. burbidgeae'', '' N. muluensis'', '' N. rajah'', '' N. tentaculata'', and '' N. × alisaputrana''. Such compounds include: * Leucocyanidin * Leucodelphinidin * Leucofisetinidin * Leucomalvidin * Leucopelargonidin * Leucopeonidin * Leucorobinetinidin * Melacacidin * Teracacidin from '' Acacia obtusifolia'' and '' Acacia maidenii'' heartwoods Leucoanthocyanidins have been demonstrated to be intermediates in anthocyanidin biosynthesis in flowers of '' Matthiola incana''. Bate-smith recommended in 1954 the use of the Forestal solvent for the isolation of leuco-anthocyanins. Metabolism Leucoanthocyanidin dioxygenase uses flavan-3,4-diols to produce 3-hydroxyanthocyanidins. The gene encoding the enzyme (PpLDOX) has been ...
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Joy Harvey
Joy Dorothy Harvey (born 1934) is an American historian of science. Life Harvey gained a PhD from Harvard University in 1983. She has been an associate editor of the Darwin Correspondence Project, and written a biography of Clémence Royer, Darwin's first French translator. She and Marilyn Bailey Ogilvie collaborated on the multi-volume ''Biographical Dictionary of Women in Science''.Pnina G. Abir-AmThe Making of a Historian of Women in Science: Marilyn Bailey Ogilvie at 80! ''History of Science Society Newsletter'', January 2018. Works * 'Medicine and politics: Dr. Mary Putnam Jacobi and the Paris Commune', ''Dialectical anthropology'', Vol. 15 (1990), p. 107–117 l'autre côté du miroir (The Other Side of the Mirror): French Neurophysiology and English Interpretations in Claude Debru, Jean Gayon and Jean-Francois Picard, eds., ''Les sciences biologiques et médicales en France, 1920-1950'', 1994. * 'Charles Darwins "Selective strategies": die französische versus die englisch ...
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Marilyn Ogilvie
Marilyn Bailey Ogilvie (born 1936) is an American historian of science known especially for her work on the history of women in science. She taught at Oklahoma Baptist University before becoming curator of the History of Science Collections and professor at the University of Oklahoma. She is currently Curator Emeritus, History of Science Collections and Professor Emeritus, Department of the History of Science at the university. Biography Dr. Ogilvie earned an A.B. degree in Biology from Baker University (1957), an M.A. in Zoology from the University of Kansas (1959), plus a Ph.D. in the History of Science (1973) and an M.A. in Library Science (1983) from the University of Oklahoma. After working as an associate professor and division chair at Oklahoma Baptist University from 1979 to 1991, Dr. Ogilvie returned to the University of Oklahoma as the Curator of the History of Science Collections. As curator, she expanded the holdings of the collection from 79,000 to 94,000 ...
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Anthocyanin
Anthocyanins (), also called anthocyans, are water-soluble vacuolar pigments that, depending on their pH, may appear red, purple, blue, or black. In 1835, the German pharmacist Ludwig Clamor Marquart gave the name Anthokyan to a chemical compound that gives flowers a blue color for the first time in his treatise "''Die Farben der Blüthen''". Food plants rich in anthocyanins include the blueberry, raspberry, black rice, and black soybean, among many others that are red, blue, purple, or black. Some of the colors of autumn leaves are derived from anthocyanins. Anthocyanins belong to a parent class of molecules called flavonoids synthesized via the phenylpropanoid pathway. They occur in all tissues of higher plants, including leaves, stems, roots, flowers, and fruits. Anthocyanins are derived from anthocyanidins by adding sugars. They are odorless and moderately astringent. Although approved as food and beverage colorant in the European Union, anthocyanins are not appr ...
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