Gero Miesenböck
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Gero Miesenböck
Gero Andreas Miesenböck (born 15 July 1965) is an Austrian scientist. He is currently Waynflete Professor of Physiology and Director of the Centre for Neural Circuits and Behaviour (CNCB) at the University of Oxford and a fellow of Magdalen College, Oxford. Education and early life A native of Austria, Miesenböck was educated at the University of Innsbruck and Umeå University in Sweden. He graduated sub auspiciis praesidentis rei publicae from the University of Innsbruck Medical School. Following his Doctor of Medicine (MD) in 1993, he undertook postdoctoral training with James Rothman. Research and career Miesenböck is known as the founder of optogenetics. He was the first scientist to modify nerve cells genetically so that their electrical activity could be controlled with light. This involved inserting DNA for light-responsive opsin proteins into the cells. Miesenböck used similar genetic modifications to breed animals whose brains contained light-responsive ne ...
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Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ...
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Rumford Prize
Founded in 1796, the Rumford Prize, awarded by the American Academy of Arts and Sciences, is one of the oldest scientific prizes in the United States. The prize recognizes contributions by scientists to the fields of heat and light. These terms are widely interpreted; awards range from discoveries in thermodynamics to improvements in the construction of steam boilers. The award was created through the endowment of US$5,000 to the Academy by Benjamin Thompson, who held the title "Count Rumford of the United Kingdom," in 1796. The terms state that the award be given to "authors of discoverie's in any part of the Continent of America, or in any of the American islands." Although it was founded in 1796, the first prize was not given until 1839, as the academy could not find anyone who, in their judgement, deserved the award. The academy found the terms of the prize to be too restrictive, and in 1832 the Supreme Court of Massachusetts allowed the Academy to change some of the provisi ...
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Neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are connected together, they form what is called a neural circuit. A typical neuron consists of a cell body (soma), dendrites, and a single axon. The soma is a compact structure, and the axon and dend ...
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Optogenetics
Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells. On the level of individual cells, light-activated enzymes and transcription factors allow precise control of biochemical signaling pathways. In systems neuroscience, the ability to control the activity of a genetically defined set of neurons has been used to understand their contribution to decision making, learning, fear memory, mating, addiction, feeding, and locomotion. In a first medical application of optogenetic technology, vision was partially restored in a blind patient. Optogenetic techniques have also been introduced to map the functional connectivity of the brain''.'' By altering the activity of genetically labelled neurons with light and using imaging and electrophysiology techniques to record the activity of other cells, researchers can identify ...
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James Rothman
James Edward Rothman (born November 3, 1950) is an American biochemist. He is the Fergus F. Wallace Professor of Biomedical Sciences at Yale University, the Chairman of the Department of Cell Biology at Yale School of Medicine, and the Director of the Nanobiology Institute at the Yale West Campus. Rothman also concurrently serves as adjunct professor of physiology and cellular biophysics at Columbia University and a research professor at the UCL Queen Square Institute of Neurology, University College London. Rothman was awarded the 2013 Nobel Prize in Physiology or Medicine, for his work on vesicle trafficking (shared with Randy Schekman and Thomas C. Südhof). He received many other honors including the King Faisal International Prize in 1996, the Louisa Gross Horwitz Prize from Columbia University and the Albert Lasker Award for Basic Medical Research both in 2002. Personal life He is the son of Martin Rothman, a pediatrician, and Gloria Hartnick. Education Rothman earned ...
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Postdoctoral Researcher
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualificati ...
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Doctor Of Medicine
Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the M.D. is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others use of M.D., is still typically titled Bachelor of Medicine, Bachelor of Surgery (M.B ...
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Sub Auspiciis Praesidentis
(Latin for ''Doctoral graduation under the auspices of the Federal President''), often abbreviated as doctoral graduation (German: ), is a special form of doctoral graduation and the highest possible distinction for academic achievements for a doctoral degree in Austria. (Monarchy) Awards comparable to the graduation can be traced back to the foundation of universities at the end of the Middle Ages and can be found in verifiable (Latin , 'emperor') since the first half of the 17th century. The is first mentioned in a document of the University of Graz, where under Emperor Ferdinand II the tribute was paid to a count in 1625. First presented in Vienna in 1661, this custom continued until the end of the Austro-Hungarian Empire. The Jesuits, to whom the University of Vienna was subordinated through the (1623–1773), seem to have contributed significantly to this development with the involvement of the court. Until the middle of the 18th century, the honour was almost excl ...
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Magdalen College, Oxford
Magdalen College (, ) is a constituent college of the University of Oxford. It was founded in 1458 by William of Waynflete. Today, it is the fourth wealthiest college, with a financial endowment of £332.1 million as of 2019 and one of the strongest academically, setting the record for the highest Norrington Score in 2010 and topping the table twice since then. It is home to several of the university's distinguished chairs, including the Agnelli-Serena Professorship, the Sherardian Professorship, and the four Waynflete Professorships. The large, square Magdalen Tower is an Oxford landmark, and it is a tradition, dating to the days of Henry VII, that the college choir sings from the top of it at 6 a.m. on May Morning. The college stands next to the River Cherwell and the University of Oxford Botanic Garden. Within its grounds are a deer park and Addison's Walk. History Foundation Magdalen College was founded in 1458 by William of Waynflete, Bishop of Winchester a ...
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Fellow
A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher educational institutions, a fellow can be a member of a highly ranked group of teachers at a particular college or university or a member of the governing body in some universities (such as the Fellows of Harvard College); it can also be a specially selected postgraduate student who has been appointed to a post (called a fellowship) granting a stipend, research facilities and other privileges for a fixed period (usually one year or more) in order to undertake some advanced study or research, often in return for teaching services. In the context of research and development-intensive large companies or corporations, the title "fellow" is sometimes given to a small number of senior scientists and engineers. In the context of medical education in No ...
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Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ...
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Waynflete Professorships
The Waynflete Professorships are four professorial fellowships at the University of Oxford endowed by Magdalen College and named in honour of the college founder William of Waynflete, who had a great interest in science. These professorships are statutory professorships of the University, that is, they are professorships established in the university's regulations, and which are by those regulations attached to Magdalen College in particular. The oldest professorship is the Waynflete Professor of Metaphysical Philosophy. The three science professorships were created following the recommendation of the University Commission in 1857, in recognition of William of Waynflete's lifetime support of science. The professorships are the Waynflete Professor of Chemistry, the Waynflete Professor of Physiology, and the Waynflete Professor of Pure Mathematics. Waynflete Professors of Metaphysical Philosophy This Waynflete Professorship is one of five statutory professorships in philosophy at the ...
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