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Gero Hütter
Gero Hütter (born 18 December 1968) is a German hematologist. Hütter and his medical team transplanted bone marrow deficient in a key HIV receptor to a leukemia patient, Timothy Ray Brown, who was also infected with human immunodeficiency virus (HIV). Subsequently, the patient's circulating HIV dropped to undetectable levels. The case was widely reported in the media, and Hütter was named one of the "Berliners of the year" for 2008 by the ''Berliner Morgenpost'', a Berlin newspaper. HIV treatment In 2009, Hütter, Eckhard Thiel and others from the Charité Hospital in Berlin, Germany, published a report on the case in the ''New England Journal of Medicine''. Their patient Timothy Ray Brown, a US citizen born in Seattle, Washington, and living in Berlin, had both acute myelogenous leukemia (AML) and HIV. The physicians found a bone marrow donor with a CCR5-Δ32 mutation in both genomic copies of a gene encoding a cell-surface chemokine receptor called CCR5. Because "most of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated between the Baltic and North seas to the north, and the Alps to the south; it covers an area of , with a population of almost 84 million within its 16 constituent states. Germany borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its financial centre is Frankfurt; the largest urban area is the Ruhr. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the bulk of the Holy Roman Empire. During the 16th ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Macrophage
Macrophages (abbreviated as M φ, MΦ or MP) ( el, large eaters, from Greek ''μακρός'' (') = large, ''φαγεῖν'' (') = to eat) are a type of white blood cell of the immune system that engulfs and digests pathogens, such as cancer cells, microbes, cellular debris, and foreign substances, which do not have proteins that are specific to healthy body cells on their surface. The process is called phagocytosis, which acts to defend the host against infection and injury. These large phagocytes are found in essentially all tissues, where they patrol for potential pathogens by amoeboid movement. They take various forms (with various names) throughout the body (e.g., histiocytes, Kupffer cells, alveolar macrophages, microglia, and others), but all are part of the mononuclear phagocyte system. Besides phagocytosis, they play a critical role in nonspecific defense (innate immunity) and also help initiate specific defense mechanisms (adaptive immunity) by recruiting other immune ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1968 Births
The year was highlighted by protests and other unrests that occurred worldwide. Events January–February * January 5 – " Prague Spring": Alexander Dubček is chosen as leader of the Communist Party of Czechoslovakia. * January 10 – John Gorton is sworn in as 19th Prime Minister of Australia, taking over from John McEwen after being elected leader of the Liberal Party the previous day, following the disappearance of Harold Holt. Gorton becomes the only Senator to become Prime Minister, though he immediately transfers to the House of Representatives through the 1968 Higgins by-election in Holt's vacant seat. * January 15 – The 1968 Belice earthquake in Sicily kills 380 and injures around 1,000. * January 21 ** Vietnam War: Battle of Khe Sanh – One of the most publicized and controversial battles of the war begins, ending on April 8. ** 1968 Thule Air Base B-52 crash: A U.S. B-52 Stratofortress crashes in Greenland, discharging 4 nuclear bombs. * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Medical Researchers
German(s) may refer to: * Germany (of or related to) ** Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Germanic peoples (Roman times) * German language **any of the Germanic languages * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (other) * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HIV/AIDS Researchers
Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual may not notice any symptoms, or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged incubation period with no symptoms. If the infection progresses, it interferes more with the immune system, increasing the risk of developing common infections such as tuberculosis, as well as other opportunistic infections, and tumors which are rare in people who have normal immune function. These late symptoms of infection are referred to as acquired immunodeficiency syndrome (AIDS). This stage is often also associated with unintended weight loss. HIV is spread primarily by unprotected sex (including anal and vaginal sex), contaminated blood transfusions, hypodermic needles, and from mother to child during ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Hematologists
German(s) may refer to: * Germany (of or related to) ** Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Germanic peoples (Roman times) * German language **any of the Germanic languages * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (other) * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Therapy
Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying human DNA was performed in 1980, by Martin Cline, but the first successful nuclear gene transfer in humans, approved by the National Institutes of Health, was performed in May 1989. The first therapeutic use of gene transfer as well as the first direct insertion of human DNA into the nuclear genome was performed by French Anderson in a trial starting in September 1990. It is thought to be able to cure many genetic disorders or treat them over time. Between 1989 and December 2018, over 2,900 clinical trials were conducted, with more than half of them in phase I.Gene Therapy Cli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ross Mirkarimi
Rostam Mirkarimi (born August 4, 1961) is an American politician and the former sheriff of San Francisco. Prior to being sheriff, he served on the San Francisco Board of Supervisors, where he represented District 5. Mirkarimi is a co-founder of the Green Party of California. Elected as a supervisor, Mirkarimi received national attention in 2007 when he introduced the first legislation prohibiting the use of non-biodegradable plastic bags by large supermarkets and drugstores, making San Francisco the first city to do so. In March 2010, Mirkarimi became a Democrat and he was elected sheriff in November 2011. He served from January to March 2012, at which time he was charged with domestic violence battery, child endangerment, and dissuading a witness in connection with a December 31, 2011 New Year's Eve altercation with his wife, and he was suspended from office pending an ethics investigation.Richmond, Josh (January 13, 2012"San Francisco sheriff Ross Mirkarimi to face misdemean ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Scientific World Journal
''The Scientific World Journal'' (formerly, ''The ScientificWorldJournal'') is a peer-reviewed scientific journal covering fields in the life sciences ranging from biomedicine to environmental sciences. It was established in 2001 and is published by Hindawi Publishing Corporation. The journal was delisted in the 2015 ''Journal Citation Reports'' (thus not receiving an impact factor) because of "anomalous citation patterns". Publication history The journal was established in 2001 and is published online and in print. From 2001 to 2011, the managing editor was Graham Lees. In 2011, the journal was acquired by Hindawi Publishing Corporation and converted to open access and to a model without an editor-in-chief. According to Institute for Scientific Information counts, the number of published items in the journal grew steadily from 141 to 227 articles per year between 2008 and 2011 and then increased over fivefold to 1,149 articles in 2011. Organization The journal was divided int ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood (journal)
''Blood'' is a peer-reviewed medical journal published by the American Society of Hematology. It was established by William Dameshek in 1946. The journal changed from semimonthly (24 times annually) to weekly publication at the start of 2009. It covers clinical and basic research in all areas of hematology, including disorders of leukocytes, both benign and malignant, erythrocytes, platelets, hemostatic mechanisms, vascular biology, immunology, and hematologic oncology. Abstracting and indexing ''Blood'' is indexed and abstracted by: According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 25.476, and has a Journal Impact Factor rank of 1/76 in the Hematology category. References External l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jay Levy
Jay A. Levy, M.D. (born November 21, 1938, Wilmington, DE) is an AIDS and cancer research physician. He is a professor of medicine with specialties in virology and immunology at the University of California, San Francisco (UCSF). Biography Levy was born in Wilmington, Delaware, with his twin brother, Stuart B. Levy. Levy received his B.A. degree with high honors from Wesleyan University (Connecticut) in 1960 and subsequently his M.D. from the College of Physicians and Surgeons at Columbia University in 1965. He conducted research for a year on regeneration in planaria at the Université de Paris (Paris, France) on Fulbright and French government fellowships. From 1961 to 1963, he was a Fellow in the School of International and Public Affairs, Columbia University, New York. He completed his internship and residency at the University of Pennsylvania Medical Center (Philadelphia) from 1965 to 1967. Levy was a staff associate at the National Cancer Institute (Bethesda MD) at th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
West Nile Virus
West Nile virus (WNV) is a single-stranded RNA virus that causes West Nile fever. It is a member of the family ''Flaviviridae'', from the genus ''Flavivirus'', which also contains the Zika virus, dengue virus, and yellow fever virus. The virus is primarily transmitted by mosquitoes, mostly species of ''Culex''. The primary hosts of WNV are birds, so that the virus remains within a "bird–mosquito–bird" transmission cycle. The virus is genetically related to the Japanese encephalitis family of viruses. Humans and horses both exhibit disease symptoms from the virus, and symptoms rarely occur in other animals. Identification of the human disease was first made in 1937 in Uganda and in the latter half of the 20th century spread to many other parts of the world. Structure Like most other flaviviruses, WNV is an enveloped virus with icosahedral symmetry. Electron microscope studies reveal a 45–50 nm virion covered with a relatively smooth protein shell; this structure i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
