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George Davis Snell
George Davis Snell NAS (December 19, 1903 – June 6, 1996) was an American mouse geneticist and basic transplant immunologist. Work George Snell shared the 1980 Nobel Prize in Physiology or Medicine with Baruj Benacerraf and Jean Dausset for their discoveries concerning "genetically determined structures on the cell surface that regulate immunological reactions". Snell specifically "discovered the genetic factors that determine the possibilities of transplanting tissue from one individual to another. It was Snell who introduced the concept of H antigensSnell's work in mice led to the discovery of Human leukocyte antigen, HLA, the major histocompatibility complex, in humans (and all vertebrates) that is analogous to the H-2 complex in mice. Recognition of these key genes was prerequisite to successful tissue and organ transplantation. Life George Snell was born in Bradford, Massachusetts, the youngest of three children. His father (who was born in Minnesota) worked as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bradford, Massachusetts
Bradford is a village and former town, in Essex County, Massachusetts, United States. Eastern Bradford is the current town of Groveland, while western Bradford was annexed by the city of Haverhill, and today consists of the part of Haverhill on the south bank of the Merrimack River. While its separate existence from Haverhill has been largely obscured, the names of many locations in the area still bear the Bradford name. History Bradford was originally part of the town of Rowley, and was called "Rowley on the Merrimack", "Rowley Village by the Merrimack", "Merrimac Lands", or just "Merrimack" before the name was changed to Bradford at a town meeting held January 7, 1672. It was named in memory of Bradford in the West Riding of Yorkshire, England, from which some of the settlers had emigrated, and first paid colonial tax on October 13, 1675. The east parish of Bradford (established in 1726) separated in 1850 and was incorporated as the town of Groveland on March 8, 1850. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jean Dausset
Jean-Baptiste-Gabriel-Joachim Dausset (19 October 1916 – 6 June 2009) was a French immunologist born in Toulouse, France. Dausset received the Nobel Prize in Physiology or Medicine in 1980 along with Baruj Benacerraf and George Davis Snell for their discovery and characterisation of the genes making the major histocompatibility complex. Using the money from his Nobel Prize and a grant from the French Television, Dausset founded the Human Polymorphism Study Center ( CEPH) in 1984, which was later renamed the Foundation Jean Dausset-CEPH in his honour. He married Rose Mayoral in 1963, with whom he had two children, Henri and Irène. Jean Dausset died on June 6, 2009 in Majorca, Spain, at the age of 92. Early life Jean-Baptiste-Gabriel-Joachim Dausset was born on 19 October 1916, in Toulouse, France. He was the youngest of four children of Henri Dausset and Elisabeth Dausset (born Renard). His father was from the Pyrénées, and was a doctor by profession, and his mother was a h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfred Nobel was a Swedish chemist, engineer, and industrialist most famously known for the invention of dynamite. He died in 1896. In his will, he bequeathed all of his "remaining realisable assets" to be used to establish five prizes which became known as "Nobel Prizes." Nobel Prizes were first awarded in 1901. Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace (Nobel characterized the Peace Prize as "to the person who has done the most or best to advance fellowship among nations, the abolition or reduction of standing armies, and the establishment and promotion of peace congresses"). In 1968, Sveriges Riksbank (Sweden's central bank) funded the establishment of the Prize in Economi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Texas
The University of Texas at Austin (UT Austin, UT, or Texas) is a public research university in Austin, Texas. It was founded in 1883 and is the oldest institution in the University of Texas System. With 40,916 undergraduate students, 11,075 graduate students and 3,133 teaching faculty as of Fall 2021, it is also the largest institution in the system. It is ranked among the top universities in the world by major college and university rankings, and admission to its programs is considered highly selective. UT Austin is considered one of the United States's Public Ivies. The university is a major center for academic research, with research expenditures totaling $679.8 million for fiscal year 2018. It joined the Association of American Universities in 1929. The university houses seven museums and seventeen libraries, including the LBJ Presidential Library and the Blanton Museum of Art, and operates various auxiliary research facilities, such as the J. J. Pickle Research Ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Linkage
Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more ''linked'' than markers that are far apart. In other words, the nearer two genes are on a chromosome, the lower the chance of recombination between them, and the more likely they are to be inherited together. Markers on different chromosomes are perfectly ''unlinked'', although the penetrance of potentially deleterious alleles may be influenced by the presence of other alleles, and these other alleles may be located on other chromosomes than that on which a particular potentially deleterious allele is located. Genetic linkage is the most prominent exception to Gregor Mendel's Law of Independent Assortment. The first experiment to demonstrate li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mendelian Inheritance
Mendelian inheritance (also known as Mendelism) is a type of biological inheritance following the principles originally proposed by Gregor Mendel in 1865 and 1866, re-discovered in 1900 by Hugo de Vries and Carl Correns, and later popularized by William Bateson. These principles were initially controversial. When Mendel's theories were integrated with the Boveri–Sutton chromosome theory of inheritance by Thomas Hunt Morgan in 1915, they became the core of classical genetics. Ronald Fisher combined these ideas with the theory of natural selection in his 1930 book ''The Genetical Theory of Natural Selection'', putting evolution onto a mathematical footing and forming the basis for population genetics within the modern evolutionary synthesis. History The principles of Mendelian inheritance were named for and first derived by Gregor Johann Mendel, a nineteenth-century Moravian monk who formulated his ideas after conducting simple hybridisation experiments with pea plants (' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bachelor's Degree
A bachelor's degree (from Middle Latin ''baccalaureus'') or baccalaureate (from Modern Latin ''baccalaureatus'') is an undergraduate academic degree awarded by colleges and universities upon completion of a course of study lasting three to six years (depending on institution and academic discipline). The two most common bachelor's degrees are the Bachelor of Arts (BA) and the Bachelor of Science (BS or BSc). In some institutions and educational systems, certain bachelor's degrees can only be taken as graduate or postgraduate educations after a first degree has been completed, although more commonly the successful completion of a bachelor's degree is a prerequisite for further courses such as a master's or a doctorate. In countries with qualifications frameworks, bachelor's degrees are normally one of the major levels in the framework (sometimes two levels where non-honours and honours bachelor's degrees are considered separately). However, some qualifications titled bachelor's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hanover, New Hampshire
Hanover is a town located along the Connecticut River in Grafton County, New Hampshire, United States. As of the 2020 census, its population was 11,870. The town is home to the Ivy League university Dartmouth College, the U.S. Army Corps of Engineers Cold Regions Research and Engineering Laboratory, and Hanover High School. The Appalachian Trail crosses the town, connecting with a number of trails and nature preserves. Most of the population resides in the Hanover census-designated place (CDP)—the main village of the town. Located at the junctions of New Hampshire routes 10, 10A, and 120, the Hanover CDP recorded a population of 9,078 people at the 2020 census. The town also contains the smaller villages of Etna and Hanover Center. History Hanover was chartered by Governor Benning Wentworth on July 4, 1761, and in 1765–1766 its first European inhabitants arrived, the majority from Connecticut. Although the surface is uneven, the town developed into an agricultural co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brookline, Massachusetts
Brookline is a town in Norfolk County, Massachusetts, Norfolk County, Massachusetts, in the United States, and part of the Greater Boston, Boston metropolitan area. Brookline borders six of Boston's neighborhoods: Brighton, Boston, Brighton, Allston, Fenway–Kenmore, Mission Hill, Boston, Mission Hill, Jamaica Plain, and West Roxbury. The city of Newton, Massachusetts, Newton lies to the west of Brookline. Brookline was first settled in 1638 as a Hamlet (place), hamlet in Boston, known as Muddy River; it was incorporated as a separate town in 1705. At the time of the 2020 United States Census, the population of the town was 63,191. It is the most populous municipality in Massachusetts to have a New England town, town (rather than city) form of government. History Once part of Algonquian peoples, Algonquian territory, Brookline was first settled by White people, European colonists in the early 17th century. The area was an outlying part of the colonial settlement of Boston a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
YMCA
YMCA, sometimes regionally called the Y, is a worldwide youth organization based in Geneva, Switzerland, with more than 64 million beneficiaries in 120 countries. It was founded on 6 June 1844 by George Williams in London, originally as the Young Men's Christian Association, and aims to put Christian values into practice by developing a healthy "body, mind, and spirit". From its inception, it grew rapidly and ultimately became a worldwide movement founded on the principles of muscular Christianity. Local YMCAs deliver projects and services focused on youth development through a wide variety of youth activities, including providing athletic facilities, holding classes for a wide variety of skills, promoting Christianity, and humanitarian work. YMCA is a non-governmental federation, with each independent local YMCA affiliated with its national organization. The national organizations, in turn, are part of both an Area Alliance (Europe, Asia Pacific, the Middle East, Af ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Minnesota
Minnesota () is a state in the upper midwestern region of the United States. It is the 12th largest U.S. state in area and the 22nd most populous, with over 5.75 million residents. Minnesota is home to western prairies, now given over to intensive agriculture; deciduous forests in the southeast, now partially cleared, farmed, and settled; and the less populated North Woods, used for mining, forestry, and recreation. Roughly a third of the state is covered in forests, and it is known as the "Land of 10,000 Lakes" for having over 14,000 bodies of fresh water of at least ten acres. More than 60% of Minnesotans live in the Minneapolis–Saint Paul metropolitan area, known as the "Twin Cities", the state's main political, economic, and cultural hub. With a population of about 3.7 million, the Twin Cities is the 16th largest metropolitan area in the U.S. Other minor metropolitan and micropolitan statistical areas in the state include Duluth, Mankato, Moorhead, Rochester, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
