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Georg Nagel
Georg Nagel (born 24 August 1953 in Weingarten, Germany) is a biophysicist and professor at the Department for Neurophysiology at the University of Würzburg in Germany. His research is focused on microbial photoreceptors and the development of optogenetic tools. Scientific career Georg Nagel studied biology and biophysics at the University of Konstanz, Germany. He received his PhD from the University of Frankfurt in 1988, working at the Max Planck Institute of Biophysics in Frankfurt. As a postdoc, he worked at Yale University and Rockefeller University, US. From 1992 to 2004, he headed an independent research group in the Department of Biophysical Chemistry at the Max Planck Institute of Biophysics in Frankfurt. Since 2004, he is a professor at the University of Würzburg, Germany, first at the Department for Molecular Plant Physiology and Biophysics, since 2019 at the Department for Neurophysiology. Research Georg Nagel, together with Peter Hegemann, is credited with the d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prof
Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital letter nearly always refers to a full professor. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Gottschalk
Alexander Gottschalk is Professor of Cellular and Molecular Neurobiology at the Goethe University in Frankfurt, Germany. Scientific career Alexander Gottschalk studied chemistry, biochemistry and immunology at Goethe University in Frankfurt, Philipps University in Marburg and University of Edinburgh, UK. His PhD thesis (Dr. rer. nat.) was conducted in the laboratory of Reinhard Lührmann at the University of Marburg. As a postdoctoral fellow, he worked with William R. Schafer at UC San Diego to study the nervous system of '' Caenorhabditis elegans''. In 2004, he became an independent research group leader in Frankfurt. In 2010, he was awarded a Heisenberg-Professor position and became Full Professor for Molecular Cell Biology and Neurobiochemistry in 2016. His researcgroupis located at the Buchmann Institute for Molecular Life Sciences. Research Alexander Gottschalk studies the neuronal control of behavior in the nematode '' Caenorhabditis elegans''. In 2005, he demonstrate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shaw Prize
The Shaw Prize is an annual award presented by the Shaw Prize Foundation. Established in 2002 in Hong Kong, it honours "individuals who are currently active in their respective fields and who have recently achieved distinguished and significant advances, who have made outstanding contributions in academic and scientific research or applications, or who in other domains have achieved excellence. The award is dedicated to furthering societal progress, enhancing quality of life, and enriching humanity's spiritual civilization." The prize has been described as the "Nobel of the East". It was founded by Hong Kong entertainment mogul and philanthropist Run Run Shaw (邵逸夫). Award The prize consists of three awards in the fields of astronomy, life science and medicine, and mathematical sciences; it is not awarded posthumously. Nominations are submitted by invited individuals beginning each year in September. Winners are announced in the summer and receive the award at a cere ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gero Miesenböck
Gero Andreas Miesenböck (born 15 July 1965) is an Austrian scientist. He is currently Waynflete Professor of Physiology and Director of the Centre for Neural Circuits and Behaviour (CNCB) at the University of Oxford and a fellow of Magdalen College, Oxford. Education and early life A native of Austria, Miesenböck was educated at the University of Innsbruck and Umeå University in Sweden. He graduated sub auspiciis praesidentis rei publicae from the University of Innsbruck Medical School. Following his Doctor of Medicine (MD) in 1993, he undertook postdoctoral training with James Rothman. Research and career Miesenböck is known as the founder of optogenetics. He was the first scientist to modify nerve cells genetically so that their electrical activity could be controlled with light. This involved inserting DNA for light-responsive opsin proteins into the cells. Miesenböck used similar genetic modifications to breed animals whose brains contained light-responsive ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward Boyden
Edward S. Boyden is an American neuroscientist at MIT. He is the Y. Eva Tan Professor in Neurotechnology, a faculty member in the MIT Media Lab and an associate member of the McGovern Institute for Brain Research. In 2018 he was named a Howard Hughes Medical Institute Investigator. He is recognized for his work on optogenetics. In this technology, a light-sensitive ion channel such as channelrhodopsin-2 is genetically expressed in neurons, allowing neuronal activity to be controlled by light. There were early efforts to achieve targeted optical control dating back to 2002 that did not involve a directly light-activated ion channel, but it was the method based on directly light-activated channels from microbes, such as channelrhodopsin, emerging in 2005 that turned out to be broadly useful. Optogenetics in this way has been widely adopted by neuroscientists as a research tool, and it is also thought to have potential therapeutic applications. Boyden joined the MIT faculty in 2007, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rumford Prize
Founded in 1796, the Rumford Prize, awarded by the American Academy of Arts and Sciences, is one of the oldest scientific prizes in the United States. The prize recognizes contributions by scientists to the fields of heat and light. These terms are widely interpreted; awards range from discoveries in thermodynamics to improvements in the construction of steam boilers. The award was created through the endowment of US$5,000 to the Academy by Benjamin Thompson, who held the title "Count Rumford of the United Kingdom," in 1796. The terms state that the award be given to "authors of discoverie's in any part of the Continent of America, or in any of the American islands." Although it was founded in 1796, the first prize was not given until 1839, as the academy could not find anyone who, in their judgement, deserved the award. The academy found the terms of the prize to be too restrictive, and in 1832 the Supreme Court of Massachusetts allowed the Academy to change some of the provisi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louis-Jeantet Prize For Medicine
Established in 1986, the Louis-Jeantet Prizes are funded by the ''Fondation Louis-Jeantet'' and awarded each year to experienced researchers who have distinguished themselves in the field of biomedical research in one of the member states of the Council of Europe. They are not intended solely as the recognition of work that has been completed, but also to encourage the continuation of innovative research projects. The prizes are awarded to fully active researchers whose scientific efforts are focused on biomedical research. When the research being recognised is close to practical applications for combating illnesses affecting humankind, one of the Louis-Jeantet Prizes converts into a Jeantet-Collen Prize for Translational Medicine, supported by generous donations from the Désiré Collen Stichting. The particular research domains in which prizes have been awarded are physiology, biophysics, structural biology, biochemistry, cellular and molecular biology, developmental biology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wiley Prize In Biomedical Sciences
The Wiley Prize in Biomedical Sciences is intended to recognize breakthrough research in pure or applied life science research that is distinguished by its excellence, originality and impact on our understanding of biological systems and processes. The award may recognize a specific contribution or series of contributions that demonstrate the nominee’s significant leadership in the development of research concepts or their clinical application. Particular emphasis will be placed on research that champions novel approaches and challenges accepted thinking in the biomedical sciences. The Wiley Foundation, established in 2001, is the endowing body that supports the Wiley Prize in Biomedical Sciences. This international award is presented annually and consists of a $35,000 prize and a luncheon in honor of the recipient. The award is presented at a ceremony at The Rockefeller University, where the recipient delivers an honorary lecture as part of the Rockefeller University Lecture Se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Second Messenger System
Second messengers are intracellular signaling molecules released by the cell in response to exposure to extracellular signaling molecules—the first messengers. (Intercellular signals, a non-local form or cell signaling, encompassing both first messengers and second messengers, are classified as autocrine, juxtacrine, paracrine, and endocrine depending on the range of the signal.) Second messengers trigger physiological changes at cellular level such as proliferation, differentiation, migration, survival, apoptosis and depolarization. They are one of the triggers of intracellular signal transduction cascades. Examples of second messenger molecules include cyclic AMP, cyclic GMP, inositol triphosphate, diacylglycerol, and calcium. First messengers are extracellular factors, often hormones or neurotransmitters, such as epinephrine, growth hormone, and serotonin. Because peptide hormones and neurotransmitters typically are biochemically hydrophilic molecules, these first messenger ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Halorhodopsin
Halorhodopsin is a light-gated ion pump, specific for chloride ions, found in archaea, known as halobacteria. It is a seven-transmembrane retinylidene protein from microbial rhodopsin family. It is similar in tertiary structure (but not primary sequence structure) to vertebrate rhodopsins, the pigments that sense light in the retina. Halorhodopsin also shares sequence similarity to channelrhodopsin, another light-driven ion channel. Halorhodopsin contains the essential light-isomerizable vitamin A derivative all-trans-retinal. Due to the intense attention on solving the structure and function of this molecule, halorhodopsin is one of the few membrane proteins whose crystal structure is known. Halorhodopsin uses the energy of green/yellow light to move chloride ions into the cell, overcoming the membrane potential. Beside chlorides it transports other halides and nitrates into the cell. Potassium chloride uptake by cells helps to maintain osmotic balance during cell growth. By ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Channelrhodopsin
Channelrhodopsins are a subfamily of retinylidene proteins ( rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes (see optogenetics). Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism ''Chlamydomonas reinhardtii'' are the first discovered channelrhodopsins. Variants that are sensitive to different colors of light or selective for specific ions (ACRs, KCRs) have been cloned from other species of algae and protists. History Phototaxis and photoorientation of microalgae have been studied over more than hundred years in many laboratories worldwide. In 1980, Ken Foster developed the first consistent theory about the functionality of algal eyes. He also analyzed published ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
