Genomics England
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Genomics England
Genomics England is a British company set up and owned by the United Kingdom Department of Health and Social Care to run the 100,000 Genomes Project. The project aimed in 2014 to sequence 100,000 genomes from NHS patients with a rare disease and their families, and patients with cancer. An infectious disease strand is being led by Public Health England. In summer 2019, Chris Wigley was appointed CEO of Genomics England, starting in October 2019. Wigley is a former McKinsey executive known for applying machine learning and artificial intelligence technology. Activity Genomics England was formally established as a company on 17 April 2013 and was formally launched on 5 July 2013 as part of the celebrations for the 65th Birthday of the UK's National Health Service In August 2014, the Wellcome Trust announced that it was investing £27 million in a genome-sequencing hub for Genomics England, allowing the company to become part of the Wellcome Trust Genome Campus, home to the Sanger ...
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100,000 Genomes Project
The 100,000 Genomes Project is a now-completed UK Government project managed by Genomics England that is sequencing whole genomes from National Health Service patients. The project is focusing on rare diseases, some common types of cancer, and infectious diseases. Participants give consent for their genome data to be linked to information about their medical condition and health records. The medical and genomic data is shared with researchers to improve knowledge of the causes, treatment and care of diseases. History The project was first announced by UK Prime Minister David Cameron in December 2012. The Government set up a new company Genomics England to oversee the project with the plan to focus on rare diseases, cancer and infectious diseases announced by Health Secretary Jeremy Hunt in July 2013. The project was also made possible by the National Institute for Health and Care Research (NIHR), NHS England, Public Health England and Health Education England. In 2015 Northe ...
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Charterhouse Square
Charterhouse Square is a garden square, a pentagonal space, in Farringdon, in the London Borough of Islington, and close to the former Smithfield Meat Market. The square is the largest courtyard or yard associated with the London Charterhouse, mostly formed of Tudor and Stuart architecture restored after the London Blitz. The square adjoins other buildings including a small school. It lies between Charterhouse Street, Carthusian Street and the main Charterhouse complex of buildings south of Clerkenwell Road. The complex includes a Chapel, Tudor Great Hall, Great Chamber, the Barts and The London School of Medicine and Dentistry and a 40-resident almshouse. The square roughly covers a large 14th-century plague pit, discovered by deep excavations for Crossrail near which, within the main site, the history of the Charterhouse is exhibited in a branch of the Museum of London. The southern end of the square forms the southern boundary of the London Borough of Islington, where it meet ...
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Secretary Of State For Health And Social Care
The secretary of state for health and social care, also referred to as the health secretary, is a secretary of state in the Government of the United Kingdom, responsible for the work of the Department of Health and Social Care. The incumbent is a member of the Cabinet of the United Kingdom. The position can trace its roots back to the nineteenth century, and has been a secretary of state position since 1968. For 30 years, from 1988 to 2018, the position was titled Secretary of State for Health, before Prime Minister Theresa May added "and Social Care" to the designation in the 2018 British cabinet reshuffle. The office holder works alongside the other health and social care ministers. The corresponding shadow minister is the shadow secretary of state for health and social care, and the secretary of state is also scrutinised by the Health and Social Care Select Committee. The current health secretary is Steve Barclay who was appointed by Rishi Sunak on 25 October 2022. Res ...
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Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-locations It is one of the largest pharmaceutical companies in the world. Novartis manufactures the drugs clozapine (Clozaril), diclofenac (Voltaren; sold to GlaxoSmithKline in 2015 deal), carbamazepine (Tegretol), valsartan (Diovan), imatinib mesylate (Gleevec/Glivec), cyclosporine (Neoral/Sandimmune), letrozole (Femara), methylphenidate (Ritalin; production ceased 2020), terbinafine (Lamisil), deferasirox (Exjade), and others. In March 1996, the companies Ciba-Geigy and Sandoz merged to form Novartis; the pharmaceutical and agrochemical divisions of both companies formed Novartis as an independent entity. Other Ciba-Geigy and Sandoz businesses were sold, or, like Ciba Specialty Chemicals, spun off as independent companies. The Sandoz brand ...
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NHS England
NHS England, officially the NHS Commissioning Board, is an executive non-departmental public body of the Department of Health and Social Care. It oversees the budget, planning, delivery and day-to-day operation of the commissioning side of the National Health Service in England as set out in the Health and Social Care Act 2012. It directly commissions NHS general practitioners, dentists, optometrists and some specialist services. The Secretary of State publishes annually a document known as the ''NHS mandate'' which specifies the objectives which the Board should seek to achieve. National Health Service (Mandate Requirements) Regulations are published each year to give legal force to the mandate. In 2018 it was announced that the organisation, while maintaining its statutory independence, would be merged with NHS Improvement, and seven "single integrated regional teams" would be jointly established. History NHS England is the operating name of the NHS Commissioning Board and ...
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Malcolm Grant
Sir Malcolm John Grant, , (born 29 November 1947) is a barrister, academic lawyer, and former law professor. Born and educated in New Zealand, he was the ninth President and Provost of University College London – the head as well as principal academic and administrative officer of the university – for over a decade from 2003 until 2013. He then served for 7 years as chairman of NHS England (previously known as the NHS Commissioning Board). He has published extensively in planning and environmental law, and local government law, including serving for 23 years (1981–2004) as the editor of the 8 loose leaf volume ''Encyclopaedia of Planning Law and Practice'' of which he remains a consultant editor. He was the Chancellor of the University of York. Early life, education and previous work Grant was born and raised in Oamaru, New Zealand. He attended the state-run Waitaki Boys' High School and was organist at St Luke’s Church. He went on to study at the University of Otag ...
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European Bioinformatics Institute
The European Bioinformatics Institute (EMBL-EBI) is an Intergovernmental Organization (IGO) which, as part of the European Molecular Biology Laboratory (EMBL) family, focuses on research and services in bioinformatics. It is located on the Wellcome Genome Campus in Hinxton near Cambridge, and employs over 600 full-time equivalent (FTE) staff. Institute leaders such as Rolf Apweiler, Alex Bateman, Ewan Birney, and Guy Cochrane, an adviser on the National Genomics Data Center Scientific Advisory Board, serve as part of the international research network of the BIG Data Center at the Beijing Institute of Genomics. Additionally, the EMBL-EBI hosts training programs that teach scientists the fundamentals of the work with biological data and promote the plethora of bioinformatic tools available for their research, both EMBL-EBI and non-EMBL-EBI-based. Bioinformatic services One of the roles of the EMBL-EBI is to index and maintain biological data in a set of databases, including E ...
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Ewan Birney
John Frederick William Birney (known as Ewan Birney) (born 6 December 1972) is joint director of EMBL's European Bioinformatics Institute (EMBL-EBI), in Hinxton, Cambridgeshire and deputy director general of the European Molecular Biology Laboratory (EMBL). He also serves as non-executive director of Genomics England, chair of the Global Alliance for Genomics and Health (GA4GH) and honorary professor of bioinformatics at the University of Cambridge. Birney has made significant contributions to genomics, through his development of innovative bioinformatics and computational biology tools. He previously served as an associate faculty member at the Wellcome Trust Sanger Institute. Education Birney was educated at Eton College as an Oppidan Scholar. Before going to university, Birney completed a gap year internship at Cold Spring Harbor Laboratory supervised by James Watson and Adrian Krainer. Birney completed his Bachelor of Arts degree in Biochemistry at the University of Oxfor ...
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Chief Medical Officer (United Kingdom)
In the United Kingdom, a Chief Medical Officer (CMO) is the most senior government advisor on matter relating to health. There are four CMOs in the United Kingdom who are appointed to advise their respective governments: * His Majesty's Government ''(CMO for England and medical adviser to the United Kingdom government)'' * Scottish Government * Welsh Government * Northern Ireland Executive Each CMO is assisted by one or more Deputy Chief Medical Officers, and complemented by a Chief Nursing Officer. The Chief Medical Officer is a qualified medical doctor whose medical speciality traditionally was public health medicine, and whose work focused on the health of communities rather than health of individuals. More recently, some appointees have been senior clinicians without training in public health medicine. In the UK, the CMO is one of the chief professional officers who advise the government in their respective health and social care disciplines. The CMO has independent st ...
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Sally Davies (doctor)
Dame Sally Claire Davies (born 24 November 1949) is a British physician and academic administrator who was the Chief Medical Officer (United Kingdom) from 2010 to 2019 and Chief Scientific Adviser at the Department of Health from 2004 to 2016 and worked as a clinician specialising in the treatment of diseases of the blood and bone marrow. She was appointed Master of Trinity College, Cambridge, on 8 February 2019, effective from 8 October 2019. She is one of the founders of the National Institute for Health and Care Research (NIHR). Early life and education Davies was born on 24 November 1949 in Birmingham, England. Her father John Gordon Davies was an Anglican priest and theologian, and her mother Emily Mary Tordoff was a scientist: they both became academics at the University of Birmingham. She failed her eleven-plus exam but was nevertheless able to study at the private Edgbaston High School for Girls in Birmingham, where she excelled on the viola. Davies studied medicine a ...
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John Bell (physician)
Sir John Irving Bell (born 1 July 1952) is a Canadian-British immunologist and geneticist. From 2006 to 2011, he was President of the United Kingdom's Academy of Medical Sciences, and since 2002 he has held the Regius Professor of Medicine (Oxford), Regius Chair of Medicine at the University of Oxford. He was since 2006 Chairman of the Office for Strategic Coordination of Health Research (OSCHR) but in 2020 became a normal member.Office for Strategic Coordination of Health Research (OSCHR)
National Health Service, consulted 12 September 2020.
Bell was selected to the Vaccine Taskforce sometime before 1 July 2020. Bell is also on the board of directors of the State-owned enterprise, SOE quango Genomics England.


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Mark Caulfield
Sir Mark Jonathan Caulfield MD, FRCP, FESC, FPharm, FBHS, FMedSci (born 19 July 1960) is a British genomic medicine researcher and Warden of Barts and The London School of Medicine and Dentistry. He is the professor of Clinical Pharmacology at the William Harvey Research Institute in Queen Mary University of London. He was awarded a knighthood in the 2019 Birthday Honours. Early life and education Caulfield was born in 1960. His Irish parents raised him in North London. He attended Bishop Douglass School in Finchley and London Hospital Medical College where he graduated with a degree in medicine in 1984. With his medical degree, Caulfield trained at St Bartholomew's Hospital where he developed a research program in molecular genetics of hypertension. Career In 2002, Caulfield was appointed Director of the William Harvey Research Institute at Queen Mary University of London. While there, he was elected to the Academy of Medical Sciences and awarded the Lilly Prize of the British ...
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