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GLIPR1
Glioma pathogenesis-related protein 1 is a protein that in humans is encoded by the ''GLIPR1'' gene. Function This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Discovery The previous finding of RTVP1 (GLIPR1) as a p53 target gene with tumor suppressor functions prompted the researches to initiate a genome-wide sequence homology search for RTVP1/GLIPR1-like (GLIPR1L) genes. p53, the tumor suppressor gene is the most commonly mutated gene in human cancer. Mutation in p53 gene can lead to cellular malfunctions such as malignant growth and metsastatis. Human GLIPR1, was initially identified in human glioblastoma and was called as GLIPR1 (glioma pathogenesis-related protein 1) or RTVP1 (related to testes-specific, vespid, and pathogenesis protein 1). Furthermore, it was identified as a marker of myelomocytic differentiation in macrophage. RTVP-1 cluster proteins share si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Structure Of GlIPR1
A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as organism, biological organisms, minerals and chemical substance, chemicals. Abstract structures include data structures in computer science and musical form. Types of structure include a hierarchy (a cascade of one-to-many relationships), a Complex network, network featuring many-to-many Link (geometry), links, or a lattice (order), lattice featuring connections between components that are neighbors in space. Load-bearing Buildings, aircraft, skeletons, Ant colony, anthills, beaver dams, bridges and salt domes are all examples of Structural load, load-bearing structures. The results of construction are divided into buildings and nonbuilding structure, non-building structures, and make up the infrastructure of a human society. Built str ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
