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Gregorio Weber
Gregorio Weber (4 July 1916 – 18 July 1997) was an Argentinian scientist who made significant contributions to the fields of fluorescence spectroscopy and protein chemistry."Biophysical Journal, Volume 75, July 1998, pages 419-421" Weber was elected to the National Academy of Sciences in 1975. Early life and education Gregorio Weber was born in Buenos Aires, Argentina in 1916. He attended the University of Buenos Aires where he received his Doctor of Medicine degree in 1942. He worked as a medical student from 1939 to 1943 in the Department of Physiology and Biochemistry as a teaching assistant for Bernardo Alberto Houssay. Houssay was renowned as a physiologist for his work on the endocrine system and in particular the pituitary gland. Weber continued his studies at the University of Cambridge under the guidance of Malcolm Dixon, well-known enzymologist, and, in 1947, earned a Ph.D. in biochemistry. His thesis, titled "Fluorescence of Riboflavin, Diaphorase and Related Substanc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urbana, Illinois
Urbana ( ) is a city in and the county seat of Champaign County, Illinois, United States. As of the 2020 census, Urbana had a population of 38,336. As of the 2010 United States Census, Urbana is the List of municipalities in Illinois, 38th-most populous municipality in Illinois. It is included in the Champaign–Urbana metropolitan area. Urbana is notable for sharing the campus of the University of Illinois Urbana-Champaign with its twin city of Champaign, Illinois, Champaign. History The Urbana area was first settled by Europeans in 1822, when it was called "Big Grove".McGinty, Alice"The Story of Champaign-Urbana" Champaign Public Library When the county of Champaign County, Illinois, Champaign was organized in 1833, the county seat was located on 40 acres of land, 20 acres donated by William T. Webber and 20 acres by Col. M. W. Busey, considered to be the city's founder, and the name "Urbana" was adopted after Urbana, Ohio, the hometown of State Senator John W. Vance, who authore ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bernardo Houssay
Bernardo Alberto Houssay (April 10, 1887 – September 21, 1971) was an Argentine physiologist. Houssay was a co-recipient of the 1947 Nobel Prize for Physiology or Medicine for discovering the role played by pituitary hormones in regulating the amount of glucose in animals, sharing the prize with Carl Ferdinand Cori and Gerty Cori. He is the first Argentine Nobel laureate in the sciences. Biography Early life Bernardo Alberto Houssay was born April 10, 1887, in Buenos Aires. His parents Albert and Clara Houssay were immigrants from France. A precocious youngster, he was admitted to the Pharmacy School at the University of Buenos Aires at 14 years of age and subsequently to the Faculty of Medicine of the same university at 17 years old and was there from 1904 to 1910. While a third-year medical student, Houssay took up a post as a research and teaching assistant in the Chair of Physiology. Career After graduating, he quickly developed and presented his M.D. thesis on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Academy Of Arts And Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other Founding Fathers of the United States. It is headquartered in Cambridge, Massachusetts. Membership in the academy is achieved through a thorough petition, review, and election process. The academy's quarterly journal, ''Dædalus'', is published by MIT Press on behalf of the academy. The academy also conducts multidisciplinary public policy research. History The Academy was established by the Massachusetts legislature on May 4, 1780, charted in order "to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people." The sixty-two incorporating fellows represented varying interests and high standing in the political, professional, and commercial secto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Repligen Corporation Award In Chemistry Of Biological Processes
The Repligen Award in Chemistry of Biological Processes was established in 1985 and consists of a silver medal and honorarium. Its purpose is to acknowledge and encourage outstanding contributions to the understanding of the chemistry of biological processes, with particular emphasis on structure, function, and mechanism. The Award is administered by the Division of Biological Chemistry of the American Chemical Society. The award was suspended in 2018 until a patron can be found. Recipients SourceACS - Division of Biological Chemistry *1986 – Gregorio Weber *1987 – Thomas C. Bruice *1988 – Robert H. Abeles *1989 – Stephen J. Benkovic *1990 – Harold A. Scheraga *1991 – William W. Parson *1992 – Frank H. Westheimer *1993 – Jeremy R. Knowles *1994 – Judith P. Klinman *1995 – W. Wallace Cleland *1996 – William P. Jencks *1997 – James A. Spudich *1998 – David S. Eisenberg *1999 – Christopher T. Walsh *2000 – Perry A. Frey *2001 – Rowena G. Ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
IAEDANS
IAEDANS is an organic fluorophore (fluorescent molecule). It stands for 5-(amino)naphthalene-1-sulfonic acid. It is widely used as a marker in fluorescence spectroscopy. 1,5-IAEDANS has a peak excitation wavelength of 336 nm and a peak emission wavelength of 490 nm. The extinction coefficient of the dye is 5700. It is soluble in dimethylformamide (DMF) or buffer above pH 6 and reacts primarily with thiols. The absorption spectrum IAEDANS overlaps well with the emission spectrum of tryptophan, making it useful as an acceptor in FRET experiments. It can also be used as a resonance energy donor to fluorophores such as fluorescein Fluorescein is an organic compound and dye based on the xanthene tricyclic structural motif, formally belonging to triarylmethine dyes family. It is available as a dark orange/red powder slightly soluble in water and alcohol. It is widely used ..., Alexa Fluor 488, Oregon Green, and BODIPY FL. References Sulfonic acids Fluorescent dye ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Illinois At Urbana–Champaign
The University of Illinois Urbana-Champaign (U of I, Illinois, University of Illinois, or UIUC) is a public land-grant research university in Illinois in the twin cities of Champaign and Urbana. It is the flagship institution of the University of Illinois system and was founded in 1867. Enrolling over 56,000 undergraduate and graduate students, the University of Illinois is one of the largest public universities by enrollment in the country. The University of Illinois Urbana-Champaign is a member of the Association of American Universities and is classified among "R1: Doctoral Universities – Very high research activity". In fiscal year 2019, research expenditures at Illinois totaled $652 million. The campus library system possesses the second-largest university library in the United States by holdings after Harvard University. The university also hosts the National Center for Supercomputing Applications and is home to the fastest supercomputer on a university campus. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Irwin Gunsalus
Irwin C. "Gunny" Gunsalus (June 29, 1912 – October 25, 2008) was an American biochemist who discovered lipoic acid, a vitamin-like substance (an enzyme cofactor) that has been used as a treatment for chronic liver disease, and pyridoxal phosphate, one of the active forms of vitamin B6. In his role as assistant secretary general at the United Nations, he led the international body's research on genetic engineering. Early life Gunsalus was born June 29, 1912, in Sully County, South Dakota, at the homestead of his family farm. His father was killed in a threshing machine accident before Gunsalus started college. He attended South Dakota State University before transferring to Cornell University, where he studied bacteriology, earning a bachelor's degree in 1933, a master's in 1937 and was awarded a doctoral degree in the field in 1940. Academic career Gunsalus taught bacteriology from 1940 to 1947 at Cornell University. There he studied issues of food safety and disease risk. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Sheffield
, mottoeng = To discover the causes of things , established = – University of SheffieldPredecessor institutions: – Sheffield Medical School – Firth College – Sheffield Technical School – University College of Sheffield , type = Public research university , academic_staff = 5,670 (2020) - including academic atypical staff , administrative_staff = , chancellor = Lady Justice Rafferty , vice_chancellor = Koen Lamberts , students = () , undergrad = () , postgrad = () , endowment = £46.7 million (2021) , budget = £741.0 million (2020–21) , city = Sheffield , state = South Yorkshire , country = England , coor = , campus = Urban , colours = Black & gold , affiliations = Russell Group WUN ACUN8 Group White Rose Sutton 30EQUISAMBAUniversities UK , website = , logo = The University of Sheffield (informally Sheffield University or TUOS) is a public research university in Sheffield, South Yorkshire, England. Its history traces back to the f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hans Adolf Krebs
Sir Hans Adolf Krebs, FRS (, ; 25 August 1900 – 22 November 1981) was a German-born British biologist, physician and biochemist. He was a pioneer scientist in the study of cellular respiration, a biochemical process in living cells that extracts energy from food and oxygen and makes it available to drive the processes of life. He is best known for his discoveries of two important sequences of chemical reactions that take place in the cells of humans and many other organisms, namely the citric acid cycle and the urea cycle. The former, often eponymously known as the "Krebs cycle", is the key sequence of metabolic reactions that provides energy in the cells of humans and other oxygen-respiring organisms; and its discovery earned Krebs a Nobel Prize in Physiology or Medicine in 1953. With Hans Kornberg, he also discovered the glyoxylate cycle, which is a slight variation of the citric acid cycle found in plants, bacteria, protists, and fungi. Krebs died in 1981 in Oxford, wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Francis Perrin (physicist)
Francis Perrin (17 August 1901 – 4 July 1992) was a French physicist, the son of Nobel prize-winning physicist Jean Perrin. Physicist Francis Perrin was born in Paris and attended École Normale Supérieure in Paris. In 1928 he obtained a doctorate in mathematical sciences from the faculté des sciences of Paris, based upon a thesis on Brownian motion and became a faculty member of Collège de France. In 1933, in connection with the neutrino, Francis Perrin estimated that "the mass must be null—or at least small compared to the mass of the electron". Subsequently he worked at the Collège de France on the fission of uranium. With Frédéric Joliot and his group, he established in 1939 the possibility of nuclear chain reactions and nuclear energy production. He was professor at the Collège de France in the chair of Atomic and Molecular Physics from 1946 to 1972. He was the French high-commissioner for atomic energy from 1951 to 1970. In 1972, he discovered the Oklo natur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dansyl Chloride
Dansyl chloride or 5-(DimethylAmino)Naphthalene-1-SulfonYL chloride is a reagent that reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green–fluorescent sulfonamide adducts. It can also be made to react with secondary amines. Dansyl chloride is widely used to modify amino acids; specifically, protein sequencing and amino acid analysis. Dansyl chloride may also be denoted DNSC. Likewise, a similar derivative, dansyl amide is known as DNSA. In addition, these protein-DNSC conjugates are sensitive to their immediate environment. This, in combination with their ability to accept energy (as in fluorescence resonance energy transfer) from the amino acid tryptophan, allows this labeling technique to be used in investigating protein folding and dynamics. The fluorescence of these sulfonamide adducts can be enhanced by adding alpha-cyclodextrin. Dansyl chloride is unstable in dimethyl sulfoxide, which should never be used to prep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
