Grass Sickness
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Grass Sickness
Grass sickness, alternatively termed equine dysautonomia, is a rare but predominantly fatal illness in horses. Grass sickness may affect all types of horse, pony and donkey, and has affected some well known horses including the thoroughbred stallions Dubai Millennium, Moorestyle and Mister Baileys. Clinical signs Grass sickness is a polyneuropathy affecting the central, peripheral and enteric nervous systems. The majority of visible clinical signs are related to paralysis within the digestive tract although nerve damage occurs throughout the body. There are three forms of grass sickness: * acute grass sickness (AGS) - horses display signs of colic and require euthanasia or die within 48 hours * subacute grass sickness (SAGS) - horses display clinical signs similar to AGS but with less severity and may survive up to 7 days * chronic grass sickness (CGS) - horses present with severe and rapid weight loss and a selected portion of these cases may survive. Clinical signs common to all ...
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Horse
The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolved over the past 45 to 55 million years from a small multi-toed creature, ''Eohippus'', into the large, single-toed animal of today. Humans began domesticating horses around 4000 BCE, and their domestication is believed to have been widespread by 3000 BCE. Horses in the subspecies ''caballus'' are domesticated, although some domesticated populations live in the wild as feral horses. These feral populations are not true wild horses, as this term is used to describe horses that have never been domesticated. There is an extensive, specialized vocabulary used to describe equine-related concepts, covering everything from anatomy to life stages, size, colors, markings, breeds, locomotion, and behavior. Horses are adapted to run, allowing them to quickly escape predators, and po ...
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Pony
A pony is a type of small horse ('' Equus ferus caballus''). Depending on the context, a pony may be a horse that is under an approximate or exact height at the withers, or a small horse with a specific conformation and temperament. Compared to a larger horse, a pony may have a thicker coat, mane and tail, with proportionally shorter legs, a wider barrel, heavier bone, a thicker neck and a shorter, broader head. The word ''pony'' derives from the old French ''poulenet'', meaning foal, a young, immature horse. Small horses and ponies were traditionally used for riding, driving and as pack beasts. During the Industrial Revolution, particularly in Great Britain, many were used as pit ponies, hauling loads of coal in the mines. In the modern era they may be kept as children's mounts, for recreational or competitive riding or driving, or for cultural or conservation reasons. Ponies are generally considered intelligent and friendly. They are sometimes also described as stubbor ...
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Donkey
The domestic donkey is a hoofed mammal in the family Equidae, the same family as the horse. It derives from the African wild ass, ''Equus africanus'', and may be classified either as a subspecies thereof, ''Equus africanus asinus'', or as a separate species, ''Equus asinus''. It was domesticated in Africa some years ago, and has been used mainly as a working animal since that time. There are more than 40 million donkeys in the world, mostly in underdeveloped countries, where they are used principally as draught or pack animals. While working donkeys are often associated with those living at or below subsistence, small numbers of donkeys or asses are kept for breeding or as pets in developed countries. A male donkey is known as a ''jack'' or ''jackass'', a female is a ''jenny'' or ''jennet'', and an immature donkey of either sex is a '' foal''. Jacks are often mated with female horses (mares) to produce '' mules''; the less common hybrid of a male horse (stallion) and j ...
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Dubai Millennium
Dubai Millennium (2 March 1996 – 29 April 2001) was a British-bred Thoroughbred racehorse and sire. The colt was trained in the United Kingdom and Dubai during his racing career from 1998 and 2000. He is notable for winning a series of major races in 1999 and 2000, including the Dubai World Cup. He died after contracting grass sickness at the age of five. Background Dubai Millennium was foaled on 20 March 1996 at the Dalham Hall Stud. He was by the Mr. Prospector stallion Seeking The Gold, out of the Prix de Pomone winner Colorado Dancer. Apart from Dubai Millennium, Seeking the Gold sired the winners of 27 Group One/Grade I races including Pleasant Home, Jazil, and Bob and John Colorado Dancer was a daughter of Fall Aspen, a highly successful broodmare who produced eight winners of Group/Graded races including Preakness Stakes winner Timber Country. Dubai Millennium was originally sent into training with David Loder at Newmarket and was ridden in all but one of his race ...
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Moorestyle
Moorestyle (1977–1984) was a British Thoroughbred racehorse and sire. He was unfashionably bred, sold cheaply as a yearling and began his career in minor races. As a three-year-old however, he improved to become the one of the outstanding British sprinters of the post-war era and was named the best horse of the year in Europe by all the major rating organisations. He was also an outstanding horse over seven furlongs. His wins that year included the July Cup at Newmarket, the Haydock Sprint Cup, the Prix de l'Abbaye and the Prix de la Forêt. He had further successes as a four-year-old and was retired to stud at the end of 1981. He had little opportunity to prove himself as a stallion, dying of grass sickness in 1984. Background Moorestyle was a bay horse bred in England by John Parker. He was sired by Manacle out of the Swedish-bred mare Guiding Star. Manacle was a sprinter whose most notable other offspring was Mendip Man, who dead-heated for first place in the Prix de l ...
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Mister Baileys
Mister Baileys (1991–2009) was a British Thoroughbred racehorse and sire. In a career that lasted from June 1993 to July 1994 he ran nine times and won four races. After winning the Vintage Stakes and the Royal Lodge Stakes as a two-year-old, he became the first Northern-trained Classic winner for seventeen years when he won the 2000 Guineas in record time on his three-year-old debut. After three further races he was retired to stud, but failed to make an impression as a sire of winners after his health was badly affected by an attack of grass sickness. He was eventually gelded in 2003 and died in 2009. Background Mister Baileys was a bay horse with a prominent white blaze and three white feet, bred by Ranston Ltd. He was sired by Robellino, a son of Roberto who won the Royal Lodge Stakes and sired several good winners including Royal Rebel ( Ascot Gold Cup) and Rebelline (Tattersalls Gold Cup). Mister Baileys was sent from Paradise Farm Stud in Dorset to the Tattersalls ...
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Polyneuropathy
Polyneuropathy ( poly- + neuro- + -pathy) is damage or disease affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain. It usually begins in the hands and feet and may progress to the arms and legs and sometimes to other parts of the body where it may affect the autonomic nervous system. It may be acute or chronic. A number of different disorders may cause polyneuropathy, including diabetes and some types of Guillain–Barré syndrome. Classification Polyneuropathies may be classified in different ways, such as by ''cause'', by ''presentation'', or by ''classes'' of polyneuropathy, in terms of which part of the nerve cell is affected mainly: the axon, the myelin sheath, or the cell body. * ''Distal axonopathy'', is the result of interrupted function of the peripheral nerves. It is the most common response of neurons to metabolic or toxic disturbances, and may be caused by metabolic ...
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Nervous System
In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body. The nervous system detects environmental changes that impact the body, then works in tandem with the endocrine system to respond to such events. Nervous tissue first arose in wormlike organisms about 550 to 600 million years ago. In vertebrates it consists of two main parts, the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord. The PNS consists mainly of nerves, which are enclosed bundles of the long fibers or axons, that connect the CNS to every other part of the body. Nerves that transmit signals from the brain are called motor nerves or '' efferent'' nerves, while those nerves that transmit information from the body to the CNS are called sensory nerves or '' afferent''. Spinal nerves are mixed nerves that serve both fu ...
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Clostridium Botulinum
''Clostridium botulinum'' is a Gram-positive, rod-shaped, anaerobic, spore-forming, motile bacterium with the ability to produce the neurotoxin botulinum. The botulinum toxin can cause botulism, a severe flaccid paralytic disease in humans and other animals, and is the most potent toxin known to mankind, natural or synthetic, with a lethal dose of 1.3–2.1 ng/kg in humans.(2010). Chapter 19. ''Clostridium'', ''Peptostreptococcus'', ''Bacteroides'', and Other Anaerobes. In Ryan K.J., Ray C (Eds), ''Sherris Medical Microbiology'', 5th ed. ''C. botulinum'' is a diverse group of pathogenic bacteria initially grouped together by their ability to produce botulinum toxin and now known as four distinct groups, ''C. botulinum'' groups I–IV, as well as some strains of ''Clostridium butyricum'' and ''Clostridium baratii'', are the bacteria responsible for producing botulinum toxin. ''C. botulinum'' is responsible for foodborne botulism (ingestion of preformed toxin), infant bot ...
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Fungi
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''t ...
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Necropsy
An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death or to evaluate any disease or injury that may be present for research or educational purposes. (The term "necropsy" is generally reserved for non-human animals). Autopsies are usually performed by a specialized medical doctor called a pathologist. In most cases, a medical examiner or coroner can determine the cause of death. However, only a small portion of deaths require an autopsy to be performed, under certain circumstances. Purposes of performance Autopsies are performed for either legal or medical purposes. Autopsies can be performed when any of the following information is desired: * Determine if death was natural or unnatural * Injury source and extent on the corpse * Manner of death must be determined * Post mortem interval * Determining the decease ...
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Laminitis
Laminitis is a disease that affects the feet of ungulates and is found mostly in horses and cattle. Clinical signs include foot tenderness progressing to inability to walk, increased digital pulses, and increased temperature in the hooves. Severe cases with outwardly visible clinical signs are known by the colloquial term ''founder'', and progression of the disease will lead to perforation of the coffin bone through the sole of the hoof or being unable to stand up, requiring euthanasia. Laminae The bones of the hoof are suspended within the axial hooves of ungulates by layers of modified skin cells, known as laminae or lamellae, which act as shock absorbers during locomotion. In horses, there are about 550–600 pairs of primary epidermal laminae, each with 150–200 secondary laminae projection from their surface. These interdigitate with equivalent structures on the surface of the coffin bone (PIII, P3, the third phalanx, pedal bone, or distal phalanx), known as dermal lamina ...
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