Granadaene
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Granadaene
Granadaene is the trivial name of a non- isoprenoid polyene that constitutes the red pigment characteristic of ''Streptococcus agalactiae'' (group B streptococcus). Characteristics Granadaene contains a conjugated system made up of a linear chain of 12 conjugated double bonds which is connected to the amino acid ornithine at one end and the sugar rhamnose at the other. Granadaene is dark red, odorless, insoluble in water, methanol, ethanol, diethyl ether, acetone, hexane, dimethyl sulfoxide (DMSO), acetonitrile, tetrahydrofuran, chloroform, and in most solvents, it is soluble in DMSO–0.1% trifluoroacetic acid (TFA). Granadaene, can be extracted from cultures of ''S.agalactiae'' in granada broth ( granada medium without agar) with 0.1 M potassium hydroxide (KOH) and purified by size-exclusion chromatography on Sephadex LH using DMSO–0.1%TFA. The ultraviolet-visible absorption spectrum of the granadaene (in DMSO/TFA) is almost identical to that of a carotene w ...
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