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Gordon Morgan Holmes
Sir Gordon Morgan Holmes, (22 February 1876 – 29 December 1965) was an Anglo-Irish neurologist. He is best known for carrying out pioneering research into the cerebellum and the visual cortex. Education He was born as the son of a Louth farmer 40 miles north of Dublin and was educated at Dundalk Educational Institution (now Dundalk Grammar School) and Trinity College, Dublin, where he graduated in medicine in 1897. Career He was initially employed at Richmond Lunatic Asylum and then, after working his way to New Zealand and back returned to studying neurology in Germany. In 1906 he was appointed Physician to the National Hospital for Nervous Diseases, Queen Square, London. At the outbreak of the First World War he was appointed as consultant neurologist to the British Expeditionary Forces. Working in a field hospital he had a unique opportunity for the investigation of the effects of lesions in specific regions of the brain on balance, vision and bladder function. While ...
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County Louth
County Louth ( ; ga, An Lú) is a coastal county in the Eastern and Midland Region of Ireland, within the province of Leinster. Louth is bordered by the counties of Meath to the south, Monaghan to the west, Armagh to the north and Down to the north-east, across Carlingford Lough. It is the smallest county in Ireland by land area and the 17th most populous, with just over 139,100 residents as of 2022. The county is named after the village of Louth. Louth County Council is the local authority for the county. History County Louth is named after the village of Louth, which in turn is named after Lugh, a god of the ancient Irish. Historically, the placename has had various spellings; , , and (see Historic Names List, for full listing). is the modern simplified spelling. The county is steeped in myth, legend and history, and is a setting in the epic. Later it saw the influence of the Vikings, as seen in the name of Carlingford Lough. They also established a longphort a ...
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Thames
The River Thames ( ), known alternatively in parts as the River Isis, is a river that flows through southern England including London. At , it is the longest river entirely in England and the second-longest in the United Kingdom, after the River Severn. The river rises at Thames Head in Gloucestershire, and flows into the North Sea near Tilbury, Essex and Gravesend, Kent, via the Thames Estuary. From the west it flows through Oxford (where it is sometimes called the Isis), Reading, Henley-on-Thames and Windsor. The Thames also drains the whole of Greater London. In August 2022, the source of the river moved five miles to beyond Somerford Keynes due to the heatwave in July 2022. The lower reaches of the river are called the Tideway, derived from its long tidal reach up to Teddington Lock. Its tidal section includes most of its London stretch and has a rise and fall of . From Oxford to the Estuary the Thames drops by 55 metres. Running through some of the drier parts of mai ...
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Holmes Tremor
Holmes tremor, first identified by Gordon Holmes in 1904, can be described as a wing-beating movement localized in the upper body that is caused by cerebellar damage. Holmes tremor is a combination of rest, action, and postural tremors. Tremor frequency ranges from 2 to 5 Hertz and is aggravated with posture and movement. It may arise from various underlying structural disorders including stroke, tumors, trauma, and other cerebellar lesions. Because Holmes tremor is rare, much of the research is based on individual cases. The formation of tremors is due to two main factors: the over-excited rhythmic movement of neuronal loops and permanent structural changes from neurodegeneration. Two major neuronal networks, the corticostriatothalamocortical hap and the inferior olivary nucleus (ION) specifically target the development of the tremors. When diagnosing a patient with Holmes tremor, one must look at the neurological signs and symptoms, as well as the possibility that the tremor is c ...
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Doyen
Doyen and doyenne (from the French word ''doyen'', ''doyenne'' in the feminine grammatical gender) is the senior ambassador by length of service in a particular country. In the English language, the meaning of doyen (feminine form: doyenne) has been borrowed from French to refer to any senior member of a group, particularly one whose knowledge or abilities exceed those of other members. In the United States and other English-speaking countries, the title of Dean is often used for the seniormost member of the diplomatic corps. In many Catholic countries, the doyen of the diplomatic corps is the Apostolic Nuncio regardless of the length of service. In a number of former colonies in Africa, the ambassador of the former metropolis holds this position. A doyen or dean can only be a diplomatic representative of the highest classan ambassador or a papal nuncio (in some Catholic countries, only a nuncio, regardless of the time of accreditation; in Togo, only the ambassador of the FRG ...
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John Hughlings Jackson
John Hughlings Jackson, FRS (4 April 1835 – 7 October 1911) was an English neurologist. He is best known for his research on epilepsy. Biography He was born at Providence Green, Green Hammerton, near Harrogate, Yorkshire, the youngest son of Samuel Jackson, a brewer and yeoman who owned and farmed his land, and Sarah Jackson (née Hughlings), the daughter of a Welsh revenue collector. His mother died just over a year after giving birth to him. He had three brothers and a sister; his brothers emigrated to New Zealand and his sister married a physician. He was educated at Tadcaster, Yorkshire and Nailsworth, Gloucestershire before attending the York Medical and Surgical School. After qualifying at St Barts in 1856 he became house physician to the York Dispensary. In 1859 he returned to London to work at the Metropolitan Free Hospital and the London Hospital. In 1862 he was appointed Assistant Physician, later (1869) full Physician at the National Hospital for Paralysis and ...
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Salvarsan
Arsphenamine, also known as Salvarsan or compound 606, is a drug that was introduced at the beginning of the 1910s as the first effective treatment for syphilis, relapsing fever, and African trypanosomiasis. This organoarsenic compound was the first modern antimicrobial agent. History Arsphenamine was first synthesized in 1907 in Paul Ehrlich's lab by Alfred Bertheim. The antisyphilitic activity of this compound was discovered by Sahachiro Hata in 1909, during a survey of hundreds of newly synthesized organic arsenical compounds. Ehrlich had theorized that by screening many compounds, a drug could be discovered that would have anti-microbial activity but not kill the human patient. Ehrlich's team began their search for such a " magic bullet" among chemical derivatives of the dangerously toxic drug atoxyl. This project was the first organized team effort to optimize the biological activity of a lead compound through systematic chemical modifications, the basis for nearly all mod ...
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Frankfurt
Frankfurt, officially Frankfurt am Main (; Hessian: , "Frank ford on the Main"), is the most populous city in the German state of Hesse. Its 791,000 inhabitants as of 2022 make it the fifth-most populous city in Germany. Located on its namesake Main River, it forms a continuous conurbation with the neighboring city of Offenbach am Main and its urban area has a population of over 2.3 million. The city is the heart of the larger Rhine-Main metropolitan region, which has a population of more than 5.6 million and is Germany's second-largest metropolitan region after the Rhine-Ruhr region. Frankfurt's central business district, the Bankenviertel, lies about northwest of the geographic center of the EU at Gadheim, Lower Franconia. Like France and Franconia, the city is named after the Franks. Frankfurt is the largest city in the Rhine Franconian dialect area. Frankfurt was a city state, the Free City of Frankfurt, for nearly five centuries, and was one of the most import ...
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Carl Weigert
Karl Weigert, Carl Weigert (19 March 1845 in Münsterberg in Silesia – 5 August 1904 in Frankfurt am Main) was a German Jewish pathologist. His nephew was Fritz Weigert and his cousin was Paul Ehrlich. He received his education at the universities of Berlin, Vienna, and Breslau, graduating in 1868. After having taken part in the Franco-Prussian war as assistant surgeon, he settled in Breslau, and for the following two years, was an assistant to Heinrich Waldeyer; from 1870 to 1874 to Hermann Lebert, and then to Julius Cohnheim, who he followed to the University of Leipzig in 1878. There he became an associate professor of pathology in 1879. In 1884, he was appointed professor of pathological anatomy at the Senkenbergsche Stiftung in Frankfurt am Main, and received the title of "Geheimer Medizinal-Rat" in 1899. He is buried in Old Jewish Cemetery, Frankfurt (Juedischer Friedhof Rat-Beil-Straße). Weigert assisted Cohnheim in many of his researches, and wrote much on th ...
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Ludwig Edinger
} Ludwig Edinger (13 April 1855 – 26 January 1918) was an influential German anatomist and neurologist and co-founder of the University of Frankfurt. In 1914 he was also appointed the first German professor of neurology. Edinger was born into a Jewish family and grew up in Worms, where his father was a successful textile salesman and democratic congressman in the state parliament of Hesse-Darmstadt. His mother was the daughter of a physician from Karlsruhe. He was not ashamed that he started his career as a poor man. Indeed, he proposed free schooling for all children in 1873, but without success. Edinger studied medicine from 1872 to 1877 in Heidelberg and Strasbourg. His studies into neurology began during his time as an assistant physician in Giessen (1877 - 1882). His habilitation was in 1881 about neurological researches. He became a docent for these themes. He worked in Berlin, Leipzig and Paris and opened his own practice for neurology in Frankfurt am Main in 1883. ...
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Castlebellingham
Castlebellingham () is a village and townland in County Louth, Republic of Ireland, Ireland. The village has become quieter since the construction of the new M1 motorway, which bypasses it. The population of Castlebellingham-Kilsaran (named for the two townlands which make up the census area) increased from 721 inhabitants as of the 2002 census to 1,126 people as of the 2016 census. History and features of note The castle of Castlebellingham served as one of the ancestral homes for members of the Bellingham family from the 17th century to the mid-20th century. The family originated in the small town of Kendal, Westmorland in England. The original ancestor of the Irish Bellinghams, Alan Bellingham, hailed from here. Henry Bellingham, a descendant of Alan was a cavalry officer who first came to Ireland during the English Civil War. The lands of Gernonstown were granted to Henry during the Cromwellian Settlement, in which a large amount of native Irish lands were given to Englishme ...
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Knighted
A knight is a person granted an honorary title of knighthood by a head of state (including the Pope) or representative for service to the monarch, the Christian denomination, church or the country, especially in a military capacity. Knighthood finds origins in the Ancient Greece, Greek ''hippeis'' and ''hoplite'' (ἱππεῖς) and Ancient Rome, Roman ''Equites, eques'' and ''centurion'' of classical antiquity. In the Early Middle Ages in Europe, knighthood was conferred upon Equestrianism, mounted warriors. During the High Middle Ages, knighthood was considered a class of lower nobility. By the Late Middle Ages, the rank had become associated with the ideals of chivalry, a code of conduct for the perfect Court (royal), courtly Christian warrior. Often, a knight was a vassal who served as an elite fighter or a bodyguard for a lord, with payment in the form of land holdings. The lords trusted the knights, who were skilled in Horses in warfare, battle on horseback. Knighthood ...
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Companion Of The Order Of St Michael And St George
The Most Distinguished Order of Saint Michael and Saint George is a British order of chivalry founded on 28 April 1818 by George IV, George IV, Prince of Wales, while he was acting as prince regent for his father, George III, King George III. It is named in honour of two military saints, Michael (archangel), Michael and Saint George, George. The Order of St Michael and St George was originally awarded to those holding commands or high position in the Mediterranean Sea, Mediterranean territories acquired in the Napoleonic Wars, and was subsequently extended to holders of similar office or position in other territories of the British Empire. It is at present awarded to men and women who hold high office or who render extraordinary or important non-military service to the United Kingdom in a foreign country, and can also be conferred for important or loyal service in relation to foreign and Commonwealth of Nations, Commonwealth affairs. Description The Order includes three class ...
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