George R. Minot
George Richards Minot (December 2, 1885 – February 25, 1950) was an American medical researcher who shared the 1934 Nobel Prize with George Hoyt Whipple and William P. Murphy for their pioneering work on pernicious anemia. Early life George Richards Minot was born in Boston, Massachusetts to James Jackson Minot (1853–1938) and Elizabeth Whitney. He was namesake of his great-great-grandfather George Richards Minot (1758–1802). His father was a physician; his father's cousin was anatomist Charles Sedgwick Minot (1852–1914); one of his great-grandfathers was James Jackson (1777–1867), co-founder of Massachusetts General Hospital. He developed interest, first, in the natural sciences, and then, in medicine. Education Minot obtained his B.A. from Harvard College in 1908, where he was elected to The Owl Club, and obtained his M.D. degree in 1912 from the Harvard Medical School. Between 1913 and 1915, he worked in the William Henry Howell's lab at Johns Hopkins School of Med ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Boston
Boston (), officially the City of Boston, is the state capital and most populous city of the Commonwealth of Massachusetts, as well as the cultural and financial center of the New England region of the United States. It is the 24th- most populous city in the country. The city boundaries encompass an area of about and a population of 675,647 as of 2020. It is the seat of Suffolk County (although the county government was disbanded on July 1, 1999). The city is the economic and cultural anchor of a substantially larger metropolitan area known as Greater Boston, a metropolitan statistical area (MSA) home to a census-estimated 4.8 million people in 2016 and ranking as the tenth-largest MSA in the country. A broader combined statistical area (CSA), generally corresponding to the commuting area and including Providence, Rhode Island, is home to approximately 8.2 million people, making it the sixth most populous in the United States. Boston is one of the oldest ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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James Jackson (physician)
James Jackson (3 October 1777 in Newburyport, Massachusetts – 27 August 1867 in Boston) was an American physician. He was a proponent of Massachusetts General Hospital and became its first physician. Life and career He was the son of Newburyport merchant Jonathan Jackson who had been a representative of Massachusetts in the Continental Congress. He graduated from Harvard in 1796, and, after teaching for a year in Leicester Academy, was employed until December 1797 as a clerk for his father, who was then an officer of the government. After studying medicine in Salem for two years, he sailed for London, where he became a “dresser” in St. Thomas's Hospital, and attended lectures there and at Guy's Hospital. He returned to Boston in 1800, and began a medical practice, which he continued until 1866. In 1803 he became a member of the Massachusetts Medical Society, and in 1810 he proposed with John Collins Warren the establishment of a hospital and an asylum for the insan ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Diabetes Mellitus
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due to lo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vitamin B12
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, in both fatty acid and amino acid metabolism. It is important in the normal functioning of the nervous system via its role in the synthesis of myelin, and in the circulatory system in the maturation of red blood cells in the bone marrow. Plants do not need cobalamin and carry out the reactions with enzymes that are not dependent on it. Vitamin B12 is the most chemically complex of all vitamins, and for humans, the only vitamin that must be sourced from animal-derived foods or from supplements. Only some archaea and bacteria can synthesize vitamin B12. Most people in developed countries get enough B12 from the consumption of meat or foods with animal sources. Foods containing vitamin B12 include meat, clams, liver, fish, poultry, eggs, and dairy products. Many breakfast cereals are ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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George H
George may refer to: People * George (given name) * George (surname) * George (singer), American-Canadian singer George Nozuka, known by the mononym George * George Washington, First President of the United States * George W. Bush, 43rd President of the United States * George H. W. Bush, 41st President of the United States * George V, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1910-1936 * George VI, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1936-1952 * Prince George of Wales * George Papagheorghe also known as Jorge / GEØRGE * George, stage name of Giorgio Moroder * George Harrison, an English musician and singer-songwriter Places South Africa * George, Western Cape ** George Airport United States * George, Iowa * George, Missouri * George, Washington * George County, Mississippi * George Air Force Base, a former U.S. Air Force base located in California Characters * George (Peppa Pig), a 2-year-old ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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United States Pharmacopeia
The ''United States Pharmacopeia'' (''USP'') is a pharmacopeia (compendium of drug information) for the United States published annually by the United States Pharmacopeial Convention (usually also called the USP), a nonprofit organization that owns the trademark and also owns the copyright on the pharmacopeia itself. The ''USP'' is published in a combined volume with the ''National Formulary'' (a formulary) as the USP-NF. If a drug ingredient or drug product has an applicable ''USP'' quality standard (in the form of a ''USP-NF'' monograph), it must conform in order to use the designation "USP" or "NF". Drugs subject to ''USP'' standards include both human drugs ( prescription, over-the-counter, or otherwise) and animal drugs. ''USP-NF'' standards also have a role in US federal law; a drug or drug ingredient with a name recognized in ''USP-NF'' is considered adulterated if it does not satisfy compendial standards for strength, quality or purity. USP also sets standards for diet ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Boston City Hospital
The Boston City Hospital (1864–1996), in Boston, Massachusetts, was a public hospital, located in the South End. It was "intended for the use and comfort of poor patients, to whom medical care will be provided at the expense of the city, and ... to provide accommodations and medical treatment to others, who do not wish to be regarded as dependent on public charity."Boston Directory (1864) In 1996, it merged with the Boston University Medical Center Hospital to form the Boston Medical Center. This building is currently under study for Boston Landmark status by the Boston Landmarks Commission. History In the mid-19th century, "the hospital was suggested ... by Elisha Goodnow, who, by his will, dated July 12, 1849, gave property to the city valued at $25,000, for establishment of a free city hospital in Wards Eleven or Twelve." Architect Gridley James Fox Bryant designed the first hospital, built 1861–1864 on Harrison Avenue in the South End. It was renovated in 1875 and aga ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alice Hamilton
Alice Hamilton (February 27, 1869Corn, JHamilton, Alice''American National Biography'' – September 22, 1970) was an American physician, research scientist, and author. She was a leading expert in the field of occupational health and a pioneer in the field of industrial toxicology. Hamilton trained at the University of Michigan Medical School. She became a professor of pathology at the Woman's Medical School of Northwestern University in 1897. In 1919, she became the first woman appointed to the faculty of Harvard University. Her scientific research focused on the study of occupational illnesses and the dangerous effects of industrial metals and chemical compounds. In addition to her scientific work, Hamilton was a social-welfare reformer, humanitarian, peace activist, and a resident-volunteer at Hull House in Chicago from 1887 to 1919. She received numerous honors and awards, including the Albert Lasker Public Service Award. Early life and family Hamilton, the second chil ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Anemia
Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen due to a lower than normal number of red blood cells, or a reduction in the amount of hemoglobin. When anemia comes on slowly, the symptoms are often vague, such as tiredness, weakness, shortness of breath, headaches, and a reduced ability to exercise. When anemia is acute, symptoms may include confusion, feeling like one is going to pass out, loss of consciousness, and increased thirst. Anemia must be significant before a person becomes noticeably pale. Symptoms of anemia depend on how quickly hemoglobin decreases. Additional symptoms may occur depending on the underlying cause. Preoperative anemia can increase the risk of needing a blood transfusion following surgery. Anemia can be temporary or long term and can range from mild to severe. Anemia can be caused by blood loss, decreased red blood cell production, and increased red blood cell breakdown. Causes o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Antithrombin
Antithrombin (AT) is a small glycoprotein that inactivates several enzymes of the coagulation system. It is a 432-amino-acid protein produced by the liver. It contains three disulfide bonds and a total of four possible glycosylation sites. α-Antithrombin is the dominant form of antithrombin found in blood plasma and has an oligosaccharide occupying each of its four glycosylation sites. A single glycosylation site remains consistently un-occupied in the minor form of antithrombin, β-antithrombin. Its activity is increased manyfold by the anticoagulant drug heparin, which enhances the binding of antithrombin to factor IIa (prothrombin) and factor Xa. Nomenclature Antithrombin is also termed antithrombin III (AT III). The designations antithrombin I through to antithrombin IV originate in early studies carried out in the 1950s by Seegers, Johnson and Fell. Antithrombin I (AT I) refers to the absorption of thrombin onto fibrin after thrombin has activated fibrinogen. Antithro ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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William Henry Howell
William Henry Howell (February 20, 1860 – February 6, 1945) was an American physiologist. He pioneered the use of heparin as a blood anti-coagulant. Early life William Henry Howell was born on February 20, 1860, in Baltimore, Maryland. He graduated from the Baltimore City College high school in 1878. He was educated at Johns Hopkins University, from which he graduated in 1881 with a Bachelor of Arts. He taught at the University of Michigan and at Harvard before becoming professor at Johns Hopkins in 1893. He received a Doctor of Medicine from the University of Michigan in 1890. He graduated with a PhD from Johns Hopkins in 1894. He also studied at Trinity College and the University of Edinburgh. Career Howell served as associate professor of physiology at Johns Hopkins in 1888 and 1889. He served as a full professor at the University of Michigan from 1889 to 1892. He then served as associate professor of physiology at Harvard Medical School from 1892 to 1893. He then moved ba ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Owl Club (Harvard)
The Owl Club is an all-male final club at Harvard University founded in 1896. History The Owl Club was founded in 1896 by Reginald Mansfield Johnson, Malcolm Scollay Greenough, Jr., Frazier Curtis, Preston Player, Charles Clifford Payson, Austen Fox Riggs, and Dudley Hall Bradlee, Jr. Originally established as a secret society, the Club held its meetings in Cambridge's Polo Club Alley before purchasing land on the corner of Holyoke Street and Holyoke Place in 1901. In 1905, architect James Purdon of Purdon & Little drew up plans for the Georgian clubhouse, and on June 24 of that year the cornerstone of the present clubhouse was laid. The new building was formally opened on March 24, 1906, the tenth anniversary of the Club. In 1916, it was voted to officially change the name from “Phi Delta Psi Club” to “Owl Club”. The club had become known as The Owl as an abbreviation of its Greek name, Ἀυλὸς χαὶ Ἔκπωμα. Notable members * Archibald C. Coolidge '87 — ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |