George Ludwig Zuelzer
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George Ludwig Zuelzer
George Ludwig Zuelzer (German spelling: Georg Ludwig Zülzer) (April 10, 1870 – October 16, 1949) was a German physician of Jewish ancestry who was a native of Berlin. He practiced medicine in Berlin until the Nazi party took power, when he emigrated 1934 to New York City. His son, Wolf William Zuelzer (1909–1987) was a noted American hematologist and pediatrician. Zülzer is remembered for his work with diabetes mellitus. He had some success using pancreatic extracts on diabetic dogs, and in 1906 injected an extract called "Acomatol" into a dying diabetic patient who was in a coma. At first the patient showed improvement, but later suffered from side effects, and died when the Acomatol supply was exhausted. Acomatol was based on an extract from calf pancreases, and was manufactured by a local company in Berlin. In a total of seven patients he observed a marked reduction of glucose and acetone in the urine. However, most patients suffered from severe side effects developing h ...
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Jewish
Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The people of the Kingdom of Israel and the ethnic and religious group known as the Jewish people that descended from them have been subjected to a number of forced migrations in their history" and Hebrews of historical History of ancient Israel and Judah, Israel and Judah. Jewish ethnicity, nationhood, and religion are strongly interrelated, "Historically, the religious and ethnic dimensions of Jewish identity have been closely interwoven. In fact, so closely bound are they, that the traditional Jewish lexicon hardly distinguishes between the two concepts. Jewish religious practice, by definition, was observed exclusively by the Jewish people, and notions of Jewish peoplehood, nation, and community were suffused with faith in the Jewish God, ...
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World War I
World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fighting occurring throughout Europe, the Middle East, Africa, the Pacific, and parts of Asia. An estimated 9 million soldiers were killed in combat, plus another 23 million wounded, while 5 million civilians died as a result of military action, hunger, and disease. Millions more died in genocides within the Ottoman Empire and in the 1918 influenza pandemic, which was exacerbated by the movement of combatants during the war. Prior to 1914, the European great powers were divided between the Triple Entente (comprising France, Russia, and Britain) and the Triple Alliance (containing Germany, Austria-Hungary, and Italy). Tensions in the Balkans came to a head on 28 June 1914, following the assassination of Archduke Franz Ferdin ...
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Jewish Emigrants From Nazi Germany To The United States
Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The people of the Kingdom of Israel and the ethnic and religious group known as the Jewish people that descended from them have been subjected to a number of forced migrations in their history" and Hebrews of historical Israel and Judah. Jewish ethnicity, nationhood, and religion are strongly interrelated, "Historically, the religious and ethnic dimensions of Jewish identity have been closely interwoven. In fact, so closely bound are they, that the traditional Jewish lexicon hardly distinguishes between the two concepts. Jewish religious practice, by definition, was observed exclusively by the Jewish people, and notions of Jewish peoplehood, nation, and community were suffused with faith in the Jewish God, the practice of Jewish (religious) la ...
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1949 Deaths
Events January * January 1 – A United Nations-sponsored ceasefire brings an end to the Indo-Pakistani War of 1947. The war results in a stalemate and the division of Kashmir, which still continues as of 2022. * January 2 – Luis Muñoz Marín becomes the first democratically elected Governor of Puerto Rico. * January 11 – The first "networked" television broadcasts take place, as KDKA-TV in Pittsburgh, Pennsylvania goes on the air, connecting east coast and mid-west programming in the United States. * January 16 – Şemsettin Günaltay forms the new government of Turkey. It is the 18th government, last single party government of the Republican People's Party. * January 17 – The first VW Type 1 to arrive in the United States, a 1948 model, is brought to New York by Dutch businessman Ben Pon. Unable to interest dealers or importers in the Volkswagen, Pon sells the sample car to pay his travel expenses. Only two 1949 models are sold in America tha ...
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1870 Births
Year 187 ( CLXXXVII) was a common year starting on Sunday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Quintius and Aelianus (or, less frequently, year 940 '' Ab urbe condita''). The denomination 187 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Septimius Severus marries Julia Domna (age 17), a Syrian princess, at Lugdunum (modern-day Lyon). She is the youngest daughter of high-priest Julius Bassianus – a descendant of the Royal House of Emesa. Her elder sister is Julia Maesa. * Clodius Albinus defeats the Chatti, a highly organized German tribe that controlled the area that includes the Black Forest. By topic Religion * Olympianus succeeds Pertinax as bishop of Byzantium (until 198). Births * Cao Pi, Chinese emperor of the Cao Wei state (d. 226) * ...
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Leonard Thompson (diabetic)
Leonard Thompson (17 July 1908 – 20 April 1935) is the first person to have received an injection of insulin as a treatment for Type 1 diabetes. Biography Thompson was first treated at SickKids hospital before being transferred to the care of physicians Andrew Almon Fletcher, Duncan Archibald Graham, and Walter Ruggles Campbell. Thompson received his first injection in Toronto, Ontario, on 11 January 1922, at 13 years of age. The first injection had an apparent impurity which was the likely cause for the allergic reaction he displayed. After a refined process was developed by James Collip to improve the canine pancreas extract, the second dosage was successfully delivered to the young patient 12 days after the first. Thompson showed signs of improved health and went on to live 13 more years taking doses of insulin, before dying of pneumonia at age 26. Until insulin was made clinically available, a diagnosis of Type 1 diabetes was a death sentence, more or less quickly (usu ...
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Charles Herbert Best
Charles Herbert Best (February 27, 1899 – March 31, 1978) was an American-Canadian medical scientist and one of the co-discoverers of insulin. Biography Born in West Pembroke, Maine on February 27, 1899 to Luella Fisher and Herbert Huestis Best, Canadian born physician from Nova Scotia. Best grew up in Pembroke before going to Toronto, Ontario to study medicine in 1915. Best married Margaret Hooper Mahon in Toronto in 1924 and they had two sons. One son, Henry Best was a well-regarded historian who later became president of Laurentian University in Sudbury, Ontario. Best's other son was Charles Alexander Best, a Canadian politician and geneticist. Best is the grandfather of Susan MacTavish Best. His father, Herbert Best, was a doctor in a small Maine town with a limited economy based mostly on sardine-packing. His mother, Lulu Newcomb, later Lulu Best, who sang soprano, accompanying herself on organ and piano, was in demand as a performer at funerals and weddings. By the ...
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Frederick Banting
Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian medical scientist, physician, painter, and Nobel laureate noted as the co-discoverer of insulin and its therapeutic potential. In 1923, Banting and John Macleod received the Nobel Prize in Medicine. Banting shared the honours and award money with his colleague, Charles Best. That same year, the government of Canada granted Banting a lifetime annuity to continue his work. As to this day, Frederick Banting, who received the Nobel Prize at age 32, remains the youngest Nobel laureate for Physiology/Medicine. Early years Frederick Banting was born on November 14, 1891, in a farmhouse near Alliston, Ontario. The youngest of five children of William Thompson Banting and Margaret Grant, he attended public high school in Alliston. In 1910, he started at Victoria College, part of the University of Toronto, in the General Arts program. After failing his first year, he petitioned to join the m ...
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Coma
A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions. Coma patients exhibit a complete absence of wakefulness and are unable to consciously feel, speak or move. Comas can be derived by natural causes, or can be medically induced. Clinically, a coma can be defined as the inability consistently to follow a one-step command. It can also be defined as a score of ≤ 8 on the Glasgow Coma Scale (GCS) lasting ≥ 6 hours. For a patient to maintain consciousness, the components of ''wakefulness'' and ''awareness'' must be maintained. Wakefulness describes the quantitative degree of consciousness, whereas awareness relates to the qualitative aspects of the functions mediated by the cortex, including cognitive abilities such as attention, sensory perception, explicit memory, language, the execution of tasks, temporal ...
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Berlin
Berlin ( , ) is the capital and largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's most populous city, according to population within city limits. One of Germany's sixteen constituent states, Berlin is surrounded by the State of Brandenburg and contiguous with Potsdam, Brandenburg's capital. Berlin's urban area, which has a population of around 4.5 million, is the second most populous urban area in Germany after the Ruhr. The Berlin-Brandenburg capital region has around 6.2 million inhabitants and is Germany's third-largest metropolitan region after the Rhine-Ruhr and Rhine-Main regions. Berlin straddles the banks of the Spree, which flows into the Havel (a tributary of the Elbe) in the western borough of Spandau. Among the city's main topographical features are the many lakes in the western and southeastern boroughs formed by the Spree, Havel and Dahme, the largest of which is Lake Müggelsee. Due to its l ...
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Diabetes In Dogs
Diabetes mellitus is a disease in which the beta cells of the endocrine pancreas either stop producing insulin or can no longer produce it in enough quantity for the body's needs. The disease can affect humans as well as animals such as dogs. The condition is treatable and need not shorten the animal's life span or interfere with quality of life. If left untreated, the condition can lead to cataracts, increasing weakness in the legs (neuropathy), malnutrition, ketoacidosis, dehydration, and death. Diabetes mainly affects middle-age and older dogs, but there are juvenile cases. (PDF) The typical canine diabetes patient is middle-age, female, and overweight at diagnosis. The number of dogs diagnosed with diabetes mellitus has increased three-fold in thirty years. In survival rates from almost the same time, only 50% survived the first 60 days after diagnosis and went on to be successfully treated at home. Currently, diabetic dogs receiving treatment have the same expected lifespan ...
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Pancreas
The pancreas is an organ of the digestive system and endocrine system of vertebrates. In humans, it is located in the abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine gland, i.e. it has both an endocrine and a digestive exocrine function. 99% of the pancreas is exocrine and 1% is endocrine. As an endocrine gland, it functions mostly to regulate blood sugar levels, secreting the hormones insulin, glucagon, somatostatin, and pancreatic polypeptide. As a part of the digestive system, it functions as an exocrine gland secreting pancreatic juice into the duodenum through the pancreatic duct. This juice contains bicarbonate, which neutralizes acid entering the duodenum from the stomach; and digestive enzymes, which break down carbohydrates, proteins, and fats in food entering the duodenum from the stomach. Inflammation of the pancreas is known as pancreatitis, with common causes including chronic alcohol use and gallstones. Becaus ...
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