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George C. Williams (biologist)
George Christopher Williams (May 12, 1926 – September 8, 2010) was an American evolutionary biologist. Williams was a professor of biology at the State University of New York at Stony Brook who was best known for his vigorous critique of group selection. The work of Williams in this area, along with W. D. Hamilton, John Maynard Smith, Richard Dawkins, and others led to the development of the gene-centered view of evolution in the 1960s. Academic work Williams' 1957 paper ''Pleiotropy, Natural Selection, and the Evolution of Senescence'' is one of the most influential in 20th century evolutionary biology, and contains at least 3 foundational ideas. The central hypothesis of antagonistic pleiotropy remains the prevailing evolutionary explanation of senescence. In this paper Williams was also the first to propose that senescence should be generally synchronized by natural selection. According to this original formulation if the adverse genic effects appeared earlier in one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charlotte, North Carolina
Charlotte ( ) is the most populous city in the U.S. state of North Carolina. Located in the Piedmont region, it is the county seat of Mecklenburg County. The population was 874,579 at the 2020 census, making Charlotte the 16th-most populous city in the U.S., the seventh most populous city in the South, and the second most populous city in the Southeast behind Jacksonville, Florida. The city is the cultural, economic, and transportation center of the Charlotte metropolitan area, whose 2020 population of 2,660,329 ranked 22nd in the U.S. Metrolina is part of a sixteen-county market region or combined statistical area with a 2020 census-estimated population of 2,846,550. Between 2004 and 2014, Charlotte was ranked as the country's fastest-growing metro area, with 888,000 new residents. Based on U.S. Census data from 2005 to 2015, Charlotte tops the U.S. in millennial population growth. It is the third-fastest-growing major city in the United States. Residents are referr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Natural Selection
Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the heritable traits characteristic of a population over generations. Charles Darwin popularised the term "natural selection", contrasting it with selective breeding, artificial selection, which in his view is intentional, whereas natural selection is not. Genetic diversity, Variation exists within all populations of organisms. This occurs partly because random mutations arise in the genome of an individual organism, and their offspring can inherit such mutations. Throughout the lives of the individuals, their genomes interact with their environments to cause variations in traits. The environment of a genome includes the molecular biology in the Cell (biology), cell, other cells, other individuals, populations, species, as well as the abiotic environment. Because individuals with certain variants of the trait tend ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doctor Of Philosophy
A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common Academic degree, degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is an earned research degree, those studying for a PhD are required to produce original research that expands the boundaries of knowledge, normally in the form of a Thesis, dissertation, and defend their work before a panel of other experts in the field. The completion of a PhD is often a requirement for employment as a university professor, researcher, or scientist in many fields. Individuals who have earned a Doctor of Philosophy degree may, in many jurisdictions, use the title ''Doctor (title), Doctor'' (often abbreviated "Dr" or "Dr.") with their name, although the proper etiquette associated with this usage may also be subject to the professional ethics of their own scholarly field, culture, or society. Those who teach at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Group Selection
Group selection is a proposed mechanism of evolution in which natural selection acts at the level of the group, instead of at the level of the individual or gene. Early authors such as V. C. Wynne-Edwards and Konrad Lorenz argued that the behavior of animals could affect their survival and reproduction as groups, speaking for instance of actions for the good of the species. In the 1930s, R.A. Fisher and J.B.S. Haldane proposed the concept of kin selection, a form of altruism from the gene-centered view of evolution, arguing that animals should sacrifice for their relatives, and thereby implying that they should not sacrifice for non-relatives. From the mid 1960s, evolutionary biologists such as John Maynard Smith, W. D. Hamilton, George C. Williams, and Richard Dawkins argued that natural selection acted primarily at the level of the gene. They argued on the basis of mathematical models that individuals would not altruistically sacrifice fitness for the sake of a group unless ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clade
A clade (), also known as a monophyletic group or natural group, is a group of organisms that are monophyletic – that is, composed of a common ancestor and all its lineal descendants – on a phylogenetic tree. Rather than the English term, the equivalent Latin term ''cladus'' (plural ''cladi'') is often used in taxonomical literature. The common ancestor may be an individual, a population, or a species (extinct or extant). Clades are nested, one in another, as each branch in turn splits into smaller branches. These splits reflect evolutionary history as populations diverged and evolved independently. Clades are termed monophyletic (Greek: "one clan") groups. Over the last few decades, the cladistic approach has revolutionized biological classification and revealed surprising evolutionary relationships among organisms. Increasingly, taxonomists try to avoid naming taxa that are not clades; that is, taxa that are not monophyletic. Some of the relationships between organisms ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evolutionary Medicine
Evolutionary medicine or Darwinian medicine is the application of modern evolutionary theory to understanding health and disease. Modern biomedical research and practice have focused on the molecular and physiological mechanisms underlying health and disease, while evolutionary medicine focuses on the question of why evolution has shaped these mechanisms in ways that may leave us susceptible to disease. The evolutionary approach has driven important advances in the understanding of cancer, autoimmune disease, and anatomy. Medical schools have been slower to integrate evolutionary approaches because of limitations on what can be added to existing medical curricula. ThInternational Society for Evolution, Medicine and Public Healthcoordinates efforts to develop the field. It owns the Oxford University Press journaEvolution, Medicine and Public HealthanThe Evolution and Medicine Review Core principles Utilizing the Delphi method, 56 experts from a variety of disciplines, includin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evolution Of Sex
Sexual reproduction is an adaptive feature which is common to almost all multicellular organisms and various unicellular organisms, with some organisms being incapable of asexual reproduction. Currently the adaptive advantage of sexual reproduction is widely regarded as a major unsolved problem in biology. As discussed below, one prominent theory is that sex evolved as an efficient mechanism for producing variation, and this had the advantage of enabling organisms to adapt to changing environments. Another prominent theory, also discussed below, is that a primary advantage of outcrossing sex is the masking of the expression of deleterious mutations. Additional theories concerning the adaptive advantage of sex are also discussed below. Sex does, however, come with a cost. In reproducing asexually, no time nor energy needs to be expended in choosing a mate. And if the environment has not changed, then there may be little reason for variation, as the organism may already be wel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Selfish Gene
''The Selfish Gene'' is a 1976 book on evolution by the ethologist Richard Dawkins, in which the author builds upon the principal theory of George C. Williams's ''Adaptation and Natural Selection'' (1966). Dawkins uses the term "selfish gene" as a way of expressing the gene-centred view of evolution (as opposed to the views focused on the organism and the group), popularising ideas developed during the 1960s by W. D. Hamilton and others. From the gene-centred view, it follows that the more two individuals are genetically related, the more sense (at the level of the genes) it makes for them to behave cooperatively with each other. A lineage is expected to evolve to maximise its inclusive fitness—the number of copies of its genes passed on globally (rather than by a particular individual). As a result, populations will tend towards an evolutionarily stable strategy. The book also introduces the term '' meme'' for a unit of human cultural evolution analogous to the gene, sugg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genes
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Selection (biology)
Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the heritable traits characteristic of a population over generations. Charles Darwin popularised the term "natural selection", contrasting it with artificial selection, which in his view is intentional, whereas natural selection is not. Variation exists within all populations of organisms. This occurs partly because random mutations arise in the genome of an individual organism, and their offspring can inherit such mutations. Throughout the lives of the individuals, their genomes interact with their environments to cause variations in traits. The environment of a genome includes the molecular biology in the cell, other cells, other individuals, populations, species, as well as the abiotic environment. Because individuals with certain variants of the trait tend to survive and reproduce more than individuals with o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adaptation
In biology, adaptation has three related meanings. Firstly, it is the dynamic evolutionary process of natural selection that fits organisms to their environment, enhancing their evolutionary fitness. Secondly, it is a state reached by the population during that process. Thirdly, it is a phenotypic trait or adaptive trait, with a functional role in each individual organism, that is maintained and has evolved through natural selection. Historically, adaptation has been described from the time of the ancient Greek philosophers such as Empedocles and Aristotle. In 18th and 19th century natural theology, adaptation was taken as evidence for the existence of a deity. Charles Darwin proposed instead that it was explained by natural selection. Adaptation is related to biological fitness, which governs the rate of evolution as measured by change in allele frequencies. Often, two or more species co-adapt and co-evolve as they develop adaptations that interlock with those of the oth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adaptation And Natural Selection
''Adaptation and Natural Selection: A Critique of Some Current Evolutionary Thought'' is a 1966 book by the American evolutionary biologist George C. Williams. Williams, in what is now considered a classic by evolutionary biologists, outlines a gene-centered view of evolution, disputes notions of evolutionary progress, and criticizes contemporary models of group selection, including the theories of Alfred Emerson, A. H. Sturtevant, and to a smaller extent, the work of V. C. Wynne-Edwards. The book takes its title from a lecture by George Gaylord Simpson in January 1947 at the Princeton University. Aspects of the book were popularised by Richard Dawkins in his 1976 book ''The Selfish Gene''. The aim of the book is to "clarify certain issues in the study of adaptation and the underlying evolutionary processes."''Adaptation and Natural Selection'', preface Though more technical than a popular science book, its target audience is not specialists but biologists in general and the mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
