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GeneMatrix
GeneMatrix Inc is a Korean company servicing molecular diagnostics. The company is listed on KOSDAQ:109820. Its main service is to diagnose DNA mutations based on its proprietary technology of restriction fragment mass polymorphism (RFMP). GeneMatrix is affiliated with the Seoul National University Medical Center, the largest oncology center in Korea. History GeneMatrix Inc was founded in 2000 by former employees of CJ CheilJedang, CJ Cheil Jedang, one of South Korea's largest conglomerates. In 2001, VARIAGENICS, INC.(NASDAQ Biotechnology Index, Nasdaq: VGNX)who was a leader in pharmacogenomics, entered into a research and development collaboration with GeneMatrix Inc which had been applying genomic technology to the development of drugs and diagnostics to treat cancer. The ultimate goal was to develop molecular diagnostic products that would predict the body's response to leading drugs in the treatment of colon and gastric cancer. WangDon Yoo, CEO and President of GeneMatri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Restriction Fragment Mass Polymorphism
Restriction Fragment Mass Polymorphism (RFMP) is a technology which Restriction digest, digests DNA into oligonucleotide fragments, and detects variation of DNA sequences by molecular weight of the fragments. RFMP is a Property, proprietary technology of GeneMatrix and can be utilized for genotyping viruses and microorganisms, and for human genome research. It is relatively restricted in usage due to the existence of many other genotyping products. Overview Restriction fragment mass polymorphism (RFMP) is an application of Maldi-TOF, matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF), used for identifying individual nucleotides from a DNA fragment, most commonly used in labeling Single-nucleotide polymorphism, single nucleotide polymorphisms (SNP). RFMP was developed as a successor to the similar restriction fragment length polymorphism (RFLP) with the intent to allow for more SNPs. Rather than read out lengths of fragments as RFLP does, the individual nucleotid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Public Company
A public company is a company whose ownership is organized via shares of stock which are intended to be freely traded on a stock exchange or in over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the United Kingdom it is usually a public limited company (plc), i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
South Korea
South Korea, officially the Republic of Korea (ROK), is a country in East Asia, constituting the southern part of the Korea, Korean Peninsula and sharing a Korean Demilitarized Zone, land border with North Korea. Its western border is formed by the Yellow Sea, while its eastern border is defined by the Sea of Japan. South Korea claims to be the sole legitimate government of the entire peninsula and List of islands of South Korea, adjacent islands. It has a Demographics of South Korea, population of 51.75 million, of which roughly half live in the Seoul Capital Area, the List of metropolitan areas by population, fourth most populous metropolitan area in the world. Other major cities include Incheon, Busan, and Daegu. The Korean Peninsula was inhabited as early as the Lower Paleolithic period. Its Gojoseon, first kingdom was noted in Chinese records in the early 7th century BCE. Following the unification of the Three Kingdoms of Korea into Unified Silla, Silla and Balhae in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotechnology
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
South Korean Won
The Korean Republic won, unofficially the South Korean won ( Symbol: ₩; Code: KRW; Korean: 대한민국 원) is the official currency of South Korea. A single won is divided into 100 jeon, the monetary subunit. The jeon is no longer used for everyday transactions, and it appears only in foreign exchange rates. The currency is issued by the Bank of Korea, based in the capital city of Seoul. Etymology The old "won" was a cognate of the Chinese yuan and Japanese yen, which were both derived from the Spanish-American silver dollar. It is derived from the hanja (, ''won''), meaning "round", which describes the shape of the silver dollar. The won was subdivided into 100 ''jeon'' (), itself a cognate of the Chinese unit of weight mace and synonymous with money in general. The current won (1962 to present) is written in hangul only and does not officially have any hanja associated with it. First South Korean won History The Korean won, Chinese yuan and Japanese yen were ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Korea
Korea ( ko, 한국, or , ) is a peninsular region in East Asia. Since 1945, it has been divided at or near the 38th parallel, with North Korea (Democratic People's Republic of Korea) comprising its northern half and South Korea (Republic of Korea) comprising its southern half. Korea consists of the Korean Peninsula, Jeju Island, and several minor islands near the peninsula. The peninsula is bordered by China to the northwest and Russia to the northeast. It is separated from Japan to the east by the Korea Strait and the Sea of Japan (East Sea). During the first half of the 1st millennium, Korea was divided between three states, Goguryeo, Baekje, and Silla, together known as the Three Kingdoms of Korea. In the second half of the 1st millennium, Silla defeated and conquered Baekje and Goguryeo, leading to the "Unified Silla" period. Meanwhile, Balhae formed in the north, superseding former Goguryeo. Unified Silla eventually collapsed into three separate states due to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
KOSDAQ
KOSDAQ (acronym of Korean Securities Dealers Automated Quotations, Korean: 코스닥) is a trading board of Korea Exchange (KRX) in South Korea established in 1996. Initially set up by Korea Financial Investment Association as an independent stock market from the Korean Stock Exchange, it was benchmarked from the American counterpart, NASDAQ. KOSDAQ is an electronic stock market, just like NASDAQ. The open hours for the market are 09:00AM to 03:30PM KST. It is now operated as SME Market Division of KRX. As of February 2021, 1476 companies are listed on KOSDAQ for trading. History The South Korean Government, in July 1986, passed the "Market Organization for Vitalization of Publicly Traded Assets for Small Businesses Act" in order to provide a way for small and intermediate businesses to raise capital through publicly traded shares, and to provide investors with new routes of investments. In April 1987, the Market Organization was achieved, and the first three companies were re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CJ CheilJedang
CJ CheilJedang is a South Korean food company based in Seoul that manufactures food ingredients, ambient, frozen and chilled packaged food products, pharmaceuticals and biotechnology. Its brands include bibigo, Gourmet and Hatbahn. bibigo brand is well known for Mandu (Korean dumpling) in the global market. History CJ Cheil Jedang was founded as 'Cheil Jedang' in August 1953 as a sugar and flour manufacturer and was originally part of Samsung Group, as their first manufacturing business. In July 1993 it spun off from Samsung and gained independent management, changing into a life and culture group with the entrance into the food service and entertainment industries. In 1996 it became the 'Cheil Jedang Group' with the official separation from Samsung Group completed in February 1997. In October 2002 the CJ Group was launched and the official name changed to 'CJ Co., Ltd'. In September 2007 CJ Co again spun off as a business holding company renamed 'CJ CheilJedang Co., Ltd' and C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NASDAQ Biotechnology Index
The NASDAQ Biotechnology Index is a stock market index made up of securities of NASDAQ-listed companies classified according to the Industry Classification Benchmark as either the Biotechnology or the Pharmaceutical industry. A list of the 213 components of the index is publisheonline Criteria In order to remain included within the index, the components must meet the following criteria: * The security U.S. listing must be exclusively on the NASDAQ National Market (unless the security was dually listed on another U.S. market prior to January 1, 2004 and has continuously maintained such listing). * The issuer of the security must be classified according to the Industry Classification Benchmark as either Biotechnology or Pharmaceuticals. * The security may not be issued by an issuer currently in bankruptcy proceedings. * The security must have a market capitalization of at least $200 million. * The security must have an average daily trading volume of at least 100,000 shares. * The issu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacogenomics
Pharmacogenomics is the study of the role of the genome in drug response. Its name ('' pharmaco-'' + ''genomics'') reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of an individual affects their response to drugs. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating DNA mutations (including single-nucleotide polymorphisms, copy number variations, and insertions/deletions) with pharmacokinetic (drug absorption, distribution, metabolism, and elimination), pharmacodynamic (effects mediated through a drug's biological targets), and/or immunogenic endpoints. Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficiency with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that pharmaceutical drug treatments can deviate from what is dubbed as the "one-dos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Papillomavirus Infection
Human papillomavirus infection (HPV infection) is caused by a DNA virus from the ''Papillomaviridae'' family. Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. In some cases, an HPV infection persists and results in either warts or precancerous lesions. These lesions, depending on the site affected, increase the risk of cancer of the cervix, vulva, vagina, penis, anus, mouth, tonsils, or throat. Nearly all cervical cancer is due to HPV and two strains – HPV16 and HPV18 – account for 70% of cases. HPV16 is responsible for almost 90% of HPV-positive oropharyngeal cancers. Between 60% and 90% of the other cancers listed above are also linked to HPV. HPV6 and HPV11 are common causes of genital warts and laryngeal papillomatosis. An HPV infection is caused by ''human papillomavirus'', a DNA virus from the papillomavirus family. Over 170 types have been described. An individual can become infected with more than one type of HPV, and the disea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oligonucleotide
Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can be manufactured as single-stranded molecules with any user-specified sequence, and so are vital for artificial gene synthesis, polymerase chain reaction (PCR), DNA sequencing, molecular cloning and as molecular probes. In nature, oligonucleotides are usually found as small RNA molecules that function in the regulation of gene expression (e.g. microRNA), or are degradation intermediates derived from the breakdown of larger nucleic acid molecules. Oligonucleotides are characterized by the sequence of nucleotide residues that make up the entire molecule. The length of the oligonucleotide is usually denoted by " -mer" (from Greek ''meros'', "part"). For example, an oligonucleotide of six nucleotides (nt) is a hexamer, while one of 25 nt wou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
