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Gaëtan Dugas
Gaëtan Dugas (; February 19, 1952 – March 30, 1984) was a Québécois Canadian flight attendant and a relatively early HIV patient who once was widely regarded as "Patient Zero," or the primary case for AIDS in the United States. This claim was later found to be incorrect. In March 1984, a Centers for Disease Control and Prevention (CDC) study tracked the sexual liaisons and practices of gay and bisexual men, especially in California and New York. Dugas was code-named "Patient O" (meaning out of state) to indicate his role in a cluster of 40 AIDS cases in the United States. This was misinterpreted as "Patient Zero" and media later extrapolated this information to mean that he was the original carrier of AIDS in the country, although the report itself made no such claim. After a new genetic analysis of stored blood samples, bolstered by some historical detective work, scientists declared that he did not bring HIV to the United States and was not Patient Zero. Dugas worke ...
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Quebec City
Quebec City ( or ; french: Ville de Québec), officially Québec (), is the capital city of the Provinces and territories of Canada, Canadian province of Quebec. As of July 2021, the city had a population of 549,459, and the Communauté métropolitaine de Québec, metropolitan area had a population of 839,311. It is the eleventhList of the largest municipalities in Canada by population, -largest city and the seventhList of census metropolitan areas and agglomerations in Canada, -largest metropolitan area in Canada. It is also the List of towns in Quebec, second-largest city in the province after Montreal. It has a humid continental climate with warm summers coupled with cold and snowy winters. The Algonquian people had originally named the area , an Algonquin language, AlgonquinThe Algonquin language is a distinct language of the Algonquian languages, Algonquian language family, and is not a misspelling. word meaning "where the river narrows", because the Saint Lawrence River na ...
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HIV/AIDS
Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual may not notice any symptoms, or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged incubation period with no symptoms. If the infection progresses, it interferes more with the immune system, increasing the risk of developing common infections such as tuberculosis, as well as other opportunistic infections, and tumors which are rare in people who have normal immune function. These late symptoms of infection are referred to as acquired immunodeficiency syndrome (AIDS). This stage is often also associated with unintended weight loss. HIV is spread primarily by unprotected sex (including anal and vaginal sex), contaminated blood transfusions, hypodermic needles, and from mother to ch ...
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Evolutionary Biology
Evolutionary biology is the subfield of biology that studies the evolutionary processes (natural selection, common descent, speciation) that produced the diversity of life on Earth. It is also defined as the study of the history of life forms on Earth. Evolution is based on the theory that all species are related and they gradually change over time. In a population, the genetic variations affect the physical characteristics i.e. phenotypes of an organism. These changes in the phenotypes will be an advantage to some organisms, which will then be passed onto their offspring. Some examples of evolution in species over many generations are the Peppered Moth and Flightless birds. In the 1930s, the discipline of evolutionary biology emerged through what Julian Huxley called the modern synthesis of understanding, from previously unrelated fields of biological research, such as genetics and ecology, systematics, and paleontology. The importance of studying Evolutionary biology is ...
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The New York Review Of Books
''The New York Review of Books'' (or ''NYREV'' or ''NYRB'') is a semi-monthly magazine with articles on literature, culture, economics, science and current affairs. Published in New York City, it is inspired by the idea that the discussion of important books is an indispensable literary activity. ''Esquire'' called it "the premier literary-intellectual magazine in the English language." In 1970, writer Tom Wolfe described it as "the chief theoretical organ of Radical Chic". The ''Review'' publishes long-form reviews and essays, often by well-known writers, original poetry, and has letters and personals advertising sections that had attracted critical comment. In 1979 the magazine founded the ''London Review of Books'', which soon became independent. In 1990 it founded an Italian edition, ''la Rivista dei Libri'', published until 2010. The ''Review'' has a book publishing division, established in 1999, called New York Review Books, which publishes reprints of classics, as well as ...
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American Journal Of Epidemiology
The American Journal of Epidemiology (''AJE'') is a peer-reviewed journal for empirical research findings, opinion pieces, and methodological developments in the field of epidemiological research. The current editor-in-chief is Dr. Enrique Schisterman. Articles published in ''AJE'' are indexed by PubMed, Embase, and a number of other databases. The ''AJE'' offers open-access options for authors. It is published monthly, with articles published online ahead of print at the accepted manuscript and corrected proof stages. Entire issues have been dedicated to abstracts from academic meetings (Society of Epidemiologic Research, North American Congress of Epidemiology), the history of the Epidemic Intelligence Service of the Centers for Disease Control and Prevention (CDC), the life of George W. Comstock, and the celebration of notable anniversaries of schools of public health ( University of California, Berkeley, School of Public Health; Tulane University School of Public Health and ...
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Index Case
The index case or patient zero is the first documented patient in a disease epidemic within a population, or the first documented patient included in an epidemiological study. It can also refer to the first case of a condition or syndrome (not necessarily contagious) to be described in the medical literature, whether or not the patient is thought to be the first person affected. An index case can achieve the status of a "classic" case study in the literature, as did Phineas Gage, the first known person to exhibit a definitive personality change as a result of a brain injury. Term The index case may or may not indicate the source of the disease, the possible spread, or which reservoir holds the disease in between outbreaks, but may bring awareness of an emerging outbreak. Earlier cases may or may not be found and are labeled primary or coprimary, secondary, tertiary, etc. The term primary case can only apply to infectious diseases that spread from human to human, and refers to t ...
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Macmillan Publishers
Macmillan Publishers (occasionally known as the Macmillan Group; formally Macmillan Publishers Ltd and Macmillan Publishing Group, LLC) is a British publishing company traditionally considered to be one of the 'Big Five' English language publishers. Founded in London in 1843 by Scottish brothers Daniel and Alexander MacMillan, the firm would soon establish itself as a leading publisher in Britain. It published two of the best-known works of Victorian era children’s literature, Lewis Carroll's ''Alice's Adventures in Wonderland'' (1865) and Rudyard Kipling's ''The Jungle Book'' (1894). Former Prime Minister of the United Kingdom, Harold Macmillan, grandson of co-founder Daniel, was chairman of the company from 1964 until his death in December 1986. Since 1999, Macmillan has been a wholly owned subsidiary of Holtzbrinck Publishing Group with offices in 41 countries worldwide and operations in more than thirty others. History Macmillan was founded in London in 1843 by Daniel ...
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How To Survive A Plague
''How to Survive a Plague'' is a 2012 American documentary film about the early years of the AIDS epidemic, and the efforts of activist groups ACT UP and TAG. It was directed by David France, a journalist who covered AIDS from its beginnings. France's first film, it was dedicated to his partner Doug Gould who died of AIDS-related pneumonia in 1992. The documentary was produced using more than 700 hours of archived footage which included news coverage, interviews as well as film of demonstrations, meetings and conferences taken by ACT UP members themselves. France says they knew what they were doing was historic, and that many of them would die. The film, which opened in select theatres across the United States on September 21, 2012, also includes footage of a demonstration during mass at St. Patrick's Cathedral in 1989. Subjects People featured in the film include: * Bill Bahlman * David Barr * Gregg Bordowitz * George H. W. Bush (archive footage) * Bill Clinton (archive foot ...
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David France (writer)
David France (born 1959) is an American investigative journalism, investigative reporter, non-fiction author, and filmmaker. He is a former ''Newsweek'' senior editor, and has published in ''New York (magazine), New York'' magazine, ''The New Yorker'', ''The New York Times Magazine'', ''GQ'', and others. France, who is gay, is best known for his investigative journalism on LGBTQ topics. He has been nominated for an Oscar and multiple Emmys, and has received two George Foster Peabody awards, a Lambda Literary Award, and the Baillie Gifford Prize for nonfiction. In June 2007, France appeared on ''The Colbert Report'' to discuss the scientific basis that homosexuality is genetics, genetic. In 2017, he appeared on Late Night with Seth Meyers to discuss his film about gay liberation activist Marsha P. Johnson. In 2009, he co-founded Public Square Films with Joy A. Tomchin. Early career Journalism France published his first pieces of reporting in Gay Community News (Boston), Gay Co ...
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Little, Brown And Company
Little, Brown and Company is an American publishing company founded in 1837 by Charles Coffin Little and James Brown in Boston. For close to two centuries it has published fiction and nonfiction by American authors. Early lists featured Emily Dickinson's poetry and ''Bartlett's Familiar Quotations''. Since 2006 Little, Brown and Company is a division of the Hachette Book Group. 19th century Little, Brown and Company had its roots in the book selling trade. It was founded in 1837 in Boston by Charles Little and James Brown. They formed the partnership "for the purpose of Publishing, Importing, and Selling Books". It can trace its roots before that to 1784 to a bookshop owned by Ebenezer Battelle on Marlborough Street. They published works of Benjamin Franklin and George Washington and they were specialized in legal publishing and importing titles. For many years, it was the most extensive law publisher in the United States, and also the largest importer of standard English law a ...
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Randy Shilts
Randy Shilts (August 8, 1951February 17, 1994) was an American journalist and author. After studying journalism at the University of Oregon, Shilts began working as a reporter for both '' The Advocate'' and the ''San Francisco Chronicle'', as well as for San Francisco Bay Area television stations. In the 1980s, he was noted for being the first openly gay reporter for the ''San Francisco Chronicle''. His first book, '' The Mayor of Castro Street: The Life and Times of Harvey Milk'', was a biography of LGBT activist Harvey Milk. His second book, ''And the Band Played On'', chronicled the history of the AIDS epidemic. Despite some controversy surrounding the book in the LGBT community, Shilts was praised for his meticulous documentation of an epidemic that was little-understood at the time. It was later made into an HBO film of the same name in 1993. His final book, '' Conduct Unbecoming: Gays and Lesbians in the US Military from Vietnam to the Persian Gulf'', examined discriminati ...
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