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GOF may refer to: * Gain-of-function, a property of a genetic mutation that changes the gene product such that its effect gets stronger (enhanced activation) or even is superseded by a different and abnormal function * ''Galaxy on Fire'', a video game series * Gamers Outreach Foundation, an American philanthropic organization * Gamo-Gofa-Dawro language, native to Ethiopia * Gang of Four (other) * General Operations Force, of the Malaysian police * Golf Street railway station, in Angus, Scotland * Goodness of fit The goodness of fit of a statistical model describes how well it fits a set of observations. Measures of goodness of fit typically summarize the discrepancy between observed values and the values expected under the model in question. Such measure ... * Grand Orient de France, a Masonic organization in France * Gulf of Finland * '' Harry Potter and the Goblet of Fire'', a 2000 novel by J. K. Rowling See also * An Gof, a Cornish militant organization {{di ...
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Gain-of-function
Gain-of-function research (GoF research or GoFR) is medical research that genetically alters an organism in a way that may enhance the biological functions of gene products. This may include an altered pathogenesis, transmissibility, or host range, i.e. the types of hosts that a microorganism can infect. This research is intended to reveal targets to better predict emerging infectious diseases and to develop vaccines and therapeutics. For example, influenza B can infect only humans and harbor seals. Introducing a mutation that would allow influenza B to infect rabbits in a controlled laboratory situation would be considered a gain-of-function experiment, as the virus did not previously have that function. That type of experiment could then help reveal which parts of the virus's genome correspond to the species that it can infect, enabling the creation of antiviral medicines which block this function. In virology, gain-of-function research is usually employed with the intention o ...
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Galaxy On Fire
A galaxy is a system of stars, stellar remnants, interstellar gas, dust, dark matter, bound together by gravity. The word is derived from the Greek ' (), literally 'milky', a reference to the Milky Way galaxy that contains the Solar System. Galaxies, averaging an estimated 100 million stars, range in size from dwarfs with less than a hundred million stars, to the largest galaxies known – supergiants with one hundred trillion stars, each orbiting its galaxy's center of mass. Most of the mass in a typical galaxy is in the form of dark matter, with only a few percent of that mass visible in the form of stars and nebulae. Supermassive black holes are a common feature at the centres of galaxies. Galaxies are categorized according to their visual morphology as elliptical, spiral, or irregular. Many are thought to have supermassive black holes at their centers. The Milky Way's central black hole, known as Sagittarius A*, has a mass four million times greater than the Sun. As of ...
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Gamers Outreach Foundation
Gamers Outreach Foundation (stylized as Gamers Outreach) is a 501(c)(3) nonprofit organization that provides entertainment to hospitalized families through video games. The organization was started in 2007 in response to a canceled Halo tournament. Present-day, Gamers Outreach oversees devices and services to help hospitals manage video game content. The organization works to help families cope with treatment inside hospitals while reinforcing healthcare staff. According to its website, Gamers Outreach programs enable as many as 3 million gaming experiences each year for patients across hundreds of healthcare facilities. History In March 2007, more than three hundred individuals had registered to participate in a ''Halo 2'' tournament organized by Saline High School student Zach Wigal. Wigal, along with a group of friends, had rented his high school's cafeteria to facilitate the event, and spent months organizing one of the area's first ever competitive video game tournaments. ...
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Gamo-Gofa-Dawro Language
Gamo-Gofa-Dawro is an Omotic language of the Afroasiatic family spoken in the Dawro, Gamo Gofa and Wolayita Zones of the Southern Nations, Nationalities, and Peoples' Region in Ethiopia. Varieties are spoken by the Gamo, Gofa, Dawro; Blench (2006) and ''Ethnologue'' treat these as separate languages. Zala presumably belongs here as well. Dialects of Dawro (Kullo-Konta) are Konta and Kucha. In 1992, Alemayehu Abebe collected a word-list of 322 entries for all three related dialects.* Alemayehu Abebe"Ometo Dialect Pilot Survey Report"SIL Electronic Survey Reports SILESR 2002-068 Notes External links * World Atlas of Language Structures The World Atlas of Language Structures (WALS) is a database of structural (phonological, grammatical, lexical) properties of languages gathered from descriptive materials. It was first published by Oxford University Press as a book with CD-ROM i ... information oGamo Languages of Ethiopia North Omotic languages {{Ethiopia ...
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Gang Of Four (other)
The Gang of Four was a political faction of four Chinese Communist Party officials, prominent during the Cultural Revolution 1966–1976. Gang of Four may also refer to: Arts and entertainment * Gang of Four (band), an English post-punk band * ''Gang of Four'' (board game), by Days of Wonder * ''Gang of Four'', 2004 novel by Liz Byrski * ''Gang of Four'' (film), a 1989 French film Political groups * Gang of Four (Afghanistan): Aslam Watanjar, Sayed Muhammad Gulabzoy, Sherjan Mazdoryar, Asadullah Sarwar * Gang of Four (Australian Labor Party): Kevin Rudd, Julia Gillard, Wayne Swan, Lindsay Tanner * Gang of Four (Australian Democrats): Lyn Allison, John Cherry, Andrew Murray, Aden Ridgeway * Gang of Four (Harlem), U.S.: David Dinkins, Basil Paterson, Charles Rangel, Percy Sutton * Gang of Four (Pakistan): two different uses to describe four generals * Gang of Four (Papua New Guinea): Mekere Morauta, Charles Lepani, Rabbie Namaliu and Anthony Siaguru * Gang of Four (pro-Contra) ...
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General Operations Force
The General Operations Force ( ms, Pasukan Gerakan Am; PGA, ''Jawi'': ڤاسوكن ڬرقن عام) is the light infantry arm of the Royal Malaysia Police. The General Operations Force was established in 1948 during the Malayan Emergency by the British Administration when Malaya was a colony. The police service was mobilised to the field role, primarily to engaging Communist guerrillas during the emerging Insurgency. When Malaysia was formed in 1963, this law enforcement unit was then known as the Police Field Force ( ms, Pasukan Medan Polis; PMP). The title was adopted when it dropped the previous handle widely referred to as the ''Jungle Squad'' ( ms, Pasukan Polis Hutan; PPH). History The Jungle Squad was established based on the Malay States Guides ( ms, Pasukan Pengawal Negeri-negeri Melayu Bersekutu) which formed in 1826. The Malay States Guides was a paramilitary force initially formed with a strength of 900 members and led by R. S. F. Walker as the first commandant. ...
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Golf Street Railway Station
, symbol_location = gb , symbol = rail , image = Golf-Street-Station-Aug2019.jpg , borough = Carnoustie, Angus , country = Scotland , coordinates = , grid_name = Grid reference , grid_position = , manager = ScotRail , platforms = 2 , code = GOF , years = 7 November 1960 , events = Opened as Golf Street Halt , years1 = 16 May 1983 , events1 = Renamed as Golf Street , mpassengers = , footnotes = Passenger statistics from the Office of Rail and Road Golf Street railway station is located on Golf Street in Carnoustie, Angus, Scotland, and serves the town's central areas. It is sited from the former Dundee East station, on the Dundee to Aberdeen line, between Barry Links and Carnoustie. ScotRail, who manage the station, operate all services. History The station opened in 1960 as ...
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Goodness Of Fit
The goodness of fit of a statistical model describes how well it fits a set of observations. Measures of goodness of fit typically summarize the discrepancy between observed values and the values expected under the model in question. Such measures can be used in statistical hypothesis testing, e.g. to test for normality of residuals, to test whether two samples are drawn from identical distributions (see Kolmogorov–Smirnov test), or whether outcome frequencies follow a specified distribution (see Pearson's chi-square test). In the analysis of variance, one of the components into which the variance is partitioned may be a lack-of-fit sum of squares. Fit of distributions In assessing whether a given distribution is suited to a data-set, the following tests and their underlying measures of fit can be used: * Bayesian information criterion *Kolmogorov–Smirnov test *Cramér–von Mises criterion *Anderson–Darling test * Shapiro–Wilk test *Chi-squared test *Akaike informat ...
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Grand Orient De France
The Grand Orient de France (GODF) is the oldest and largest of several Freemasonry, Freemasonic organizations based in France and is the oldest in Continental Europe (as it was formed out of an older Grand Lodge of France in 1773, and briefly absorbed the rump of the older body in 1799, allowing it to date its foundation to 1728 or 1733). The Grand Orient de France is generally regarded as the "mother lodge" of Continental Freemasonry. History Foundation In 1777, the Grand Orient de France recognised the antiquity of the ''Lodge of Perfect Equality'', said to have been formed in 1688. This, if it actually existed at that time, was a military lodge attached to the Arthur Forbes, 1st Earl of Granard, Earl of Granard's Royal Irish Regiment (1684–1922), Royal Irish Regiment, formed by King Charles II of England, Charles II of England in Saint-Germain in 1661, just before his return to England. The regiment remained loyal to the Stuarts, and did not return to France until after th ...
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Gulf Of Finland
The Gulf of Finland ( fi, Suomenlahti; et, Soome laht; rus, Фи́нский зали́в, r=Finskiy zaliv, p=ˈfʲinskʲɪj zɐˈlʲif; sv, Finska viken) is the easternmost arm of the Baltic Sea. It extends between Finland to the north and Estonia to the south, to Saint Petersburg in Russia to the east, where the river Neva drains into it. Other major cities around the gulf include Helsinki and Tallinn. The eastern parts of the Gulf of Finland belong to Russia, and some of Russia's most important oil harbors are located farthest in, near Saint Petersburg (including Primorsk). As the seaway to Saint Petersburg, the Gulf of Finland has been and continues to be of considerable strategic importance to Russia. Some of the environmental problems affecting the Baltic Sea are at their most pronounced in the shallow gulf. Proposals for a tunnel through the gulf have been made. Geography The gulf has an area of . The length (from the Hanko Peninsula to Saint Petersburg) is and t ...
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Harry Potter And The Goblet Of Fire
''Harry Potter and the Goblet of Fire'' is a fantasy novel written by British author J. K. Rowling and the fourth novel in the ''Harry Potter'' series. It follows Harry Potter, a wizard in his fourth year at Hogwarts School of Witchcraft and Wizardry, and the mystery surrounding the entry of Harry's name into the Triwizard Tournament, in which he is forced to compete. The book was published in the United Kingdom by Bloomsbury and in the United States by Scholastic. In both countries, the release date was 8 July 2000. This was the first time a book in the series was published in both countries at the same time. The novel won a Hugo Award, the only ''Harry Potter'' novel to do so, in 2001. The book was adapted into a film, released worldwide on 18 November 2005, and a video game by Electronic Arts. Plot Background Throughout the three previous novels in the ''Harry Potter'' series, the main character, Harry Potter, has struggled with the difficulties of growing up and the add ...
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