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GNRH2
Progonadoliberin-2 is a protein that in humans is encoded by the ''GNRH2'' gene. The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone, QHWSHGWYPG. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. Three transcript variants that encode unique proproteins but the same peptide hormone have been found for this gene. The peptide belongs to gonadotropin-releasing hormone family The gonadotropin-releasing hormones (GnRH) (gonadoliberin) are a family of peptides that play a pivotal role in reproduction. The main function of GnRH is to act on the pituitary to stimulate the synthesis and secretion of luteinizing and foll .... References Further reading * * * * * * * * * * * * * * * Precursor proteins Decapeptides {{gene-20-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gonadotropin-releasing Hormone Family
The gonadotropin-releasing hormones (GnRH) (gonadoliberin) are a family of peptides that play a pivotal role in reproduction. The main function of GnRH is to act on the pituitary to stimulate the synthesis and secretion of luteinizing and follicle-stimulating hormones, but GnRH also acts on the brain, retina, sympathetic nervous system, gonads, and placenta in certain species. There seems to be at least three forms of GnRH. The second form is expressed in midbrain and seems to be widespread. The third form has been found so far only in fish. GnRH is a C-terminal amidated decapeptide processed from a larger precursor protein. Four of the ten residues are perfectly conserved in all species where GnRH has been sequenced. Subfamilies *Gonadoliberin I Human proteins containing this domain GNRH1, GNRH2 Progonadoliberin-2 is a protein that in humans is encoded by the ''GNRH2'' gene. The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa pepti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Precursor Proteins
Precursor or Precursors may refer to: *Precursor (religion), a forerunner, predecessor ** The Precursor, John the Baptist Science and technology * Precursor (bird), a hypothesized genus of fossil birds that was composed of fossilized parts of unrelated animals * Precursor (chemistry), a compound that participates in the chemical reaction that produces another compound * Precursor (physics), a phenomenon of wave propagation in dispersive media * Precursor in the course of a disease, a state preceding a particular stage in that course * Precursor cell (biology), a unipotent stem cell * Earthquake precursor, a diagnostic phenomenon that can occur before an earthquake * Gehrlein Precursor, a glider * LNWR Precursor Class (other), classes of passenger locomotives developed for the London and North Western Railway Fiction *Precursors Halo (series), an extremely advanced race that preceded and were destroyed by The Forerunners * ''Precursor'' (novel), a 1999 novel set in C. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
