Fritz Lipmann
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Fritz Lipmann
Fritz Albert Lipmann (; June 12, 1899 – July 24, 1986) was a German-American biochemist and a co-discoverer in 1945 of coenzyme A. For this, together with other research on coenzyme A, he was awarded the Nobel Prize in Physiology or Medicine in 1953 (shared with Hans Adolf Krebs). Early life and education Lipmann was born in Königsberg, Germany, to a Jewish family. His parents were Gertrud (Lachmanski) and Leopold Lipmann, an attorney. Lipmann studied medicine at the University of Königsberg, Berlin, and Munich, graduating in Berlin in 1924. He returned to Königsberg to study chemistry under Professor Hans Meerwein. In 1926 he joined Otto Meyerhof at the Kaiser Wilhelm Institute for Biology, Dahlem, Berlin, for his doctoral thesis. After that he followed Meyerhof to Heidelberg to the Kaiser Wilhelm Institute for Medical Research. Career From 1939 on, Lipmann lived and worked in the United States. He was a Research Associate in the Department of Biochemistry, Cornell Univer ...
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Königsberg
Königsberg (, ) was the historic Prussian city that is now Kaliningrad, Russia. Königsberg was founded in 1255 on the site of the ancient Old Prussian settlement ''Twangste'' by the Teutonic Knights during the Northern Crusades, and was named in honour of King Ottokar II of Bohemia. A Baltic port city, it successively became the capital of the Królewiec Voivodeship, the State of the Teutonic Order, the Duchy of Prussia and the provinces of East Prussia and Prussia. Königsberg remained the coronation city of the Prussian monarchy, though the capital was moved to Berlin in 1701. Between the thirteenth and the twentieth centuries, the inhabitants spoke predominantly German, but the multicultural city also had a profound influence upon the Lithuanian and Polish cultures. The city was a publishing center of Lutheran literature, including the first Polish translation of the New Testament, printed in the city in 1551, the first book in Lithuanian and the first Lutheran catechism, ...
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Hans Adolf Krebs
Sir Hans Adolf Krebs, FRS (, ; 25 August 1900 – 22 November 1981) was a German-born British biologist, physician and biochemist. He was a pioneer scientist in the study of cellular respiration, a biochemical process in living cells that extracts energy from food and oxygen and makes it available to drive the processes of life. He is best known for his discoveries of two important sequences of chemical reactions that take place in the cells of humans and many other organisms, namely the citric acid cycle and the urea cycle. The former, often eponymously known as the "Krebs cycle", is the key sequence of metabolic reactions that provides energy in the cells of humans and other oxygen-respiring organisms; and its discovery earned Krebs a Nobel Prize in Physiology or Medicine in 1953. With Hans Kornberg, he also discovered the glyoxylate cycle, which is a slight variation of the citric acid cycle found in plants, bacteria, protists, and fungi. Krebs died in 1981 in Oxford, wh ...
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National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ...
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American Academy Of Arts And Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other Founding Fathers of the United States. It is headquartered in Cambridge, Massachusetts. Membership in the academy is achieved through a thorough petition, review, and election process. The academy's quarterly journal, ''Dædalus'', is published by MIT Press on behalf of the academy. The academy also conducts multidisciplinary public policy research. History The Academy was established by the Massachusetts legislature on May 4, 1780, charted in order "to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people." The sixty-two incorporating fellows represented varying interests and high standing in the political, professional, and commercial secto ...
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Pantethine
Pantethine (bis-pantethine or co-enzyme pantethine) is a dimeric form of pantetheine, which is produced from pantothenic acid (vitamin B5) by the addition of cysteamine. Pantethine was discovered by Gene Brown, a PhD student at the time. Pantethine is two molecules of pantetheine linked by a disulfide bridge. Pantetheine is an intermediate in the production of coenzyme A by the body. Most vitamin B5 supplements are in the form of calcium pantothenate, a salt of pantothenic acid, with doses in the range of 5 to 10 mg/day. In contrast, pantethine is sold as a dietary supplement for lowering blood cholesterol and triglycerides at doses of 500 to 1200 mg/day. Dietary supplement Pantethine is available in the United States as a dietary supplement because of evidence for lowering elevated LDL-cholesterol and triglycerides and raising HDL-cholesterol. In multiple clinical trials of patients with elevated cholesterol and triglycerides, total and LDL cholesterol were decreased ...
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New York, New York
New York, often called New York City or NYC, is the most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the most densely populated major city in the United States, and is more than twice as populous as second-place Los Angeles. New York City lies at the southern tip of New York State, and constitutes the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the world by urban landmass. With over 20.1 million people in its metropolitan statistical area and 23.5 million in its combined statistical area as of 2020, New York is one of the world's most populous megacities, and over 58 million people live within of the city. New York City is a global cultural, financial, entertainment, and media center with a significant influence on commerce, health care and life sciences, research, technology, education, ...
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Rockefeller University
The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classified among "R2: Doctoral Universities – High research activity." Rockefeller is the oldest biomedical research institute in the United States. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Sciences, 17 members of the National Academy of Medicine, seven Lasker Award recipients, and five Nobel laureates. As of March 2022, a total of 26 Nobel laureates have been affiliated with Rockefeller University. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine' ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
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Cornell University Medical College
The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York. Weill Cornell Medicine is affiliated with NewYork-Presbyterian Hospital, Weill Cornell Medical Center, Hospital for Special Surgery, Memorial Sloan Kettering Cancer Center, and Rockefeller University, all of which are located nearby on York Avenue. Weill Cornell's clinical affiliates rank highly, with the NewYork-Presbyterian Hospital ranked #1 in the region and #4 in the nation, the Hospital for Special Surgery ranked #1 in the nation for orthopedics and the Memorial Sloan Kettering Center #2 for cancer. Memorial Sloan Kettering Cancer Center and Rockefeller University joined Weill Cornell to establish the Tri-Institutional MD–PhD Program in 1991. In 2001, the school opened a campus in Qatar. Weill Cornell has also been affiliated with Houston Methodist Hospital since 2004. On S ...
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Heidelberg
Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914, of which roughly a quarter consisted of students. Located about south of Frankfurt, Heidelberg is the List of cities in Baden-Württemberg by population, fifth-largest city in Baden-Württemberg. Heidelberg is part of the densely populated Rhine-Neckar, Rhine-Neckar Metropolitan Region. Heidelberg University, founded in 1386, is Germany's oldest and one of Europe's most reputable universities. Heidelberg is a Science, scientific hub in Germany and home to several internationally renowned #Research, research facilities adjacent to its university, including the European Molecular Biology Laboratory and four Max Planck Society, Max Planck Institutes. The city has also been a hub for the arts, especially literature, throughout the centurie ...
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Dahlem (Berlin)
Dahlem ( or ) is a locality of the Steglitz-Zehlendorf borough in southwestern Berlin. Until Berlin's 2001 administrative reform it was a part of the former borough of Zehlendorf. It is located between the mansion settlements of Grunewald and Lichterfelde West. Dahlem is one of the most affluent parts of the city and a center for academic research. It is home to the Freie Universität Berlin, with its architecturally significant Philological Library ''("The Brain")''. Several other research institutions and museums, as well as parts of the Grunewald forest with its renaissance hunting lodge, are located in Dahlem. The U3 line of the Berlin U-Bahn system connects Dahlem to central Berlin. History The first written account of Dahlem dates to the year 1275. The history of the village is connected to the Dahlem Demesne (''Domäne Dahlem'') first mentioned in 1450. Its estates were sold to the state of Prussia in 1841 and developed by dividing it into lots for building villas ...
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Otto Meyerhof
Otto Fritz Meyerhof (; April 12, 1884 – October 6, 1951) was a German physician and biochemist who won the 1922 Nobel Prize in Physiology and Medicine. Biography Otto Fritz Meyerhof was born in Hannover, at Theaterplatz 16A (now:Rathenaustrasse 16A), the son of wealthy Jewish parents. In 1888, his family moved to Berlin, where Otto spent most of his childhood, and where he started his study of medicine. He continued these studies in Strasbourg and Heidelberg, from which he graduated in 1909, with a work titled "Contributions to the Psychological Theory of Mental Illness". In Heidelberg, he met Hedwig Schallenberg. They married in 1914 and became parents of a daughter, Bettina, and two sons, Gottfried (who referred, after emigration, to himself as Geoffrey) as well as Walter. In 1912, Otto Meyerhof moved to the University of Kiel, where he received a professorship in 1918. In 1922, he was awarded the Nobel Prize in Medicine, with Archibald Vivian Hill, for his work on muscle met ...
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