FAM40A
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FAM40A
Protein FAM40A is a protein that is located on chromosome 1 in humans and is encoded by the ''FAM40A'' gene. Characteristics and secondary structure FAM40A has an isoelectric point of 5.92 and a molecular weight of 95,575 daltons. It is predicted to have three transmembrane domains, making it a transmembrane protein. FAM40A does not contain a signal peptide and is also predicted to bind to DNA, possibly making it a membrane protein in the nuclear membrane. The secondary structure of FAM40A is predicted to contain twenty-six alpha helices and two beta sheets. The 5' untranslated region of FAM40A is predicted to contain one stem-loop and the 3' untranslated region is predicted to contain eight stem-loop structures. Two miRNAs are predicted to bind to two of the stem-loop structures present in the 3' UTR region. Homology FAM40A has no paralogs. However, it does have orthologs stretching all the way back to yeast. It has been suggested that FAM40A is a homolog to the yeast gene FA ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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MiRNA
MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. Found in plants, animals and some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary sequences in mRNA molecules, then gene silence said mRNA molecules by one or more of the following processes: (1) cleavage of mRNA strand into two pieces, (2) destabilization of mRNA by shortening its poly(A) tail, or (3) translation of mRNA into proteins. This last method of gene silencing is the least efficient of the three, and requires the aid of ribosomes. miRNAs resemble the small interfering RNAs (siRNAs) of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts that fold back on themselves to form short hairpins, whereas siRNAs derive from longer regions of double-stranded RNA. The human genome may encode over 1900 miRNAs, although more recent analysis suggests that ...
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Monodelphis Domestica
The gray short-tailed opossum (''Monodelphis domestica'') is a small South American member of the family Didelphidae. Unlike most other marsupials, the gray short-tailed opossum does not have a true pouch. The scientific name ''Monodelphis'' is derived from Greek and means "single womb" (referring to the lack of a pouch) and the Latin word ''domestica'' which means "domestic" (chosen because of the species' habit of entering human dwellings). It was the first marsupial to have its genome sequenced. The gray short-tailed opossum is used as a research model in science, and is also frequently found in the exotic pet trade. It is also known as the Brazilian opossum, rainforest opossum and in a research setting the laboratory opossum. Description Gray short-tailed opossums are relatively small animals, with a superficial resemblance to voles. In the wild they have head-body length of and weigh ; males are larger than females. However, individuals kept in captivity are typically mu ...
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Rattus Norvegicus
''Rattus'' is a genus of muroid rodents, all typically called rats. However, the term rat can also be applied to rodent species outside of this genus. Species and description The best-known ''Rattus'' species are the black rat (''R. rattus'') and the brown rat (''R. norvegicus''). The group is generally known as the Old World rats or true rats and originated in Asia. Rats are bigger than most Old World mice, which are their relatives, but seldom weigh over in the wild. Taxonomy of ''Rattus'' The genus ''Rattus'' is a member of the giant subfamily Murinae. Several other murine genera are sometimes considered part of ''Rattus'': ''Lenothrix'', ''Anonymomys'', ''Sundamys'', ''Kadarsanomys'', ''Diplothrix'', ''Margaretamys'', ''Lenomys'', ''Komodomys'', ''Palawanomys'', ''Bunomys'', ''Nesoromys'', ''Stenomys'', ''Taeromys'', ''Paruromys'', ''Abditomys'', ''Tryphomys'', ''Limnomys'', ''Tarsomys'', '' Bullimus'', ''Apomys'', ''Millardia'', '' Srilankamys'', ''Niviventer'', ''Maxomy ...
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Mus Musculus
Mus or MUS may refer to: Abbreviations * MUS, the NATO country code for Mauritius * MUS, the IATA airport code for Minami Torishima Airport * MUS, abbreviation for the Centre for Modern Urban Studies on Campus The Hague, Leiden University, Netherlands * MUS, abbreviation for Medically unexplained physical symptoms * MUS, abbreviation for the Memphis University School * MUS, abbreviation for the Movimiento Unión Soberanista * MUS, abbreviation for Multiple-use water supply system, a low-cost, equitable water supply systems * Mus, abbreviation for Musca, a southern constellation * mus, ISO-639 code for the Muscogee language * Mus., abbreviation used in music degrees such as B.Mus. and M.Mus. * MUs, or million units of energy, used in India for a gigawatt hour People * Anders Mus (fl. 1501–1535), Danish civil servant in Norway * Conny Mus (1950–2010), Dutch journalist, best known as a correspondent for ''RTL Nieuws'' in Israel and the Middle East * Gus Mus (born 1944), I ...
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Equus Caballus
The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolved over the past 45 to 55 million years from a small multi-toed creature, ''Eohippus'', into the large, single-toed animal of today. Humans began domesticating horses around 4000 BCE, and their domestication is believed to have been widespread by 3000 BCE. Horses in the subspecies ''caballus'' are domesticated, although some domesticated populations live in the wild as feral horses. These feral populations are not true wild horses, as this term is used to describe horses that have never been domesticated. There is an extensive, specialized vocabulary used to describe equine-related concepts, covering everything from anatomy to life stages, size, colors, markings, breeds, locomotion, and behavior. Horses are adapted to run, allowing them to quickly escape predators, and poss ...
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Sus Scrofa
The wild boar (''Sus scrofa''), also known as the wild swine, common wild pig, Eurasian wild pig, or simply wild pig, is a suid native to much of Eurasia and North Africa, and has been introduced to the Americas and Oceania. The species is now one of the widest-ranging mammals in the world, as well as the most widespread suiform. It has been assessed as least concern on the IUCN Red List due to its wide range, high numbers, and adaptability to a diversity of habitats. It has become an invasive species in part of its introduced range. Wild boars probably originated in Southeast Asia during the Early Pleistocene and outcompeted other suid species as they spread throughout the Old World. , up to 16 subspecies are recognized, which are divided into four regional groupings based on skull height and lacrimal bone length. The species lives in matriarchal societies consisting of interrelated females and their young (both male and female). Fully grown males are usually solitary outsid ...
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Pongo Abelii
The Sumatran orangutan (''Pongo abelii'') is one of the three species of orangutans. Critically Endangered, and found only in the north of the Indonesian island of Sumatra, it is rarer than the Bornean orangutan but more common than the recently identified Tapanuli orangutan, also found in Sumatra. Its common name is based on two separate local words, "''orang''" ("people" or "person") and "''hutan''" ("forest"), derived from Malay, and translates as 'person of the forest'. Description Male Sumatran orangutans grow to about tall and , while females are smaller, averaging and . Compared to the Bornean species, Sumatran orangutans are thinner and have longer faces; their hair is longer with a paler red color. Behaviour and ecology Compared with the Bornean orangutan, the Sumatran orangutan tends to be more frugivorous and especially insectivorous. Preferred fruits include figs and jackfruits. It will also eat bird eggs and small vertebrates. Sumatran orangutans spend far less ...
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Homo Sapiens
Humans (''Homo sapiens'') are the most abundant and widespread species of primate, characterized by bipedalism and exceptional cognitive skills due to a large and complex brain. This has enabled the development of advanced tools, culture, and language. Humans are highly social and tend to live in complex social structures composed of many cooperating and competing groups, from families and kinship networks to political states. Social interactions between humans have established a wide variety of values, social norms, and rituals, which bolster human society. Its intelligence and its desire to understand and influence the environment and to explain and manipulate phenomena have motivated humanity's development of science, philosophy, mythology, religion, and other fields of study. Although some scientists equate the term ''humans'' with all members of the genus ''Homo'', in common usage, it generally refers to ''Homo sapiens'', the only extant member. Anatomically mod ...
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BLAT (bioinformatics)
BLAT (BLAST-like alignment tool) is a pairwise sequence alignment algorithm that was developed by Jim Kent at the University of California Santa Cruz (UCSC) in the early 2000s to assist in the assembly and annotation of the human genome. It was designed primarily to decrease the time needed to align millions of mouse genomic reads and expressed sequence tags against the human genome sequence. The alignment tools of the time were not capable of performing these operations in a manner that would allow a regular update of the human genome assembly. Compared to pre-existing tools, BLAT was ~500 times faster with performing mRNA/ DNA alignments and ~50 times faster with protein/protein alignments. Overview BLAT is one of multiple algorithms developed for the analysis and comparison of biological sequences such as DNA, RNA and proteins, with a primary goal of inferring homology in order to discover biological function of genomic sequences. It is not guaranteed to find the mathematicall ...
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BLAST
Blast or The Blast may refer to: * Explosion, a rapid increase in volume and release of energy in an extreme manner *Detonation, an exothermic front accelerating through a medium that eventually drives a shock front Film * ''Blast'' (1997 film), starring Andrew Divoff * ''Blast'' (2000 film), starring Liesel Matthews * ''Blast'' (2004 film), an action comedy film * ''Blast!'' (1972 film) or ''The Final Comedown'', an American drama * ''BLAST!'' (2008 film), a documentary about the BLAST telescope * '' A Blast'', a 2014 film directed by Syllas Tzoumerkas Magazines * ''Blast'' (magazine), a 1914–15 literary magazine of the Vorticist movement * ''Blast'' (U.S. magazine), a 1933–34 American short-story magazine * ''The Blast'' (magazine), a 1916–17 American anarchist periodical Music * Blast (American band), a hardcore punk band * Blast (Russian band), an indie band * ''Blast'' (album), by Holly Johnson, 1989 * ''The Blast'' (album), by Yuvan Shankar Raja, 1999 * " ...
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Homolog
In biology, homology is similarity due to shared ancestry between a pair of structures or genes in different taxa. A common example of homologous structures is the forelimbs of vertebrates, where the wings of bats and birds, the arms of primates, the front flippers of whales and the forelegs of four-legged vertebrates like dogs and crocodiles are all derived from the same ancestral tetrapod structure. Evolutionary biology explains homologous structures adapted to different purposes as the result of descent with modification from a common ancestor. The term was first applied to biology in a non-evolutionary context by the anatomist Richard Owen in 1843. Homology was later explained by Charles Darwin's theory of evolution in 1859, but had been observed before this, from Aristotle onwards, and it was explicitly analysed by Pierre Belon in 1555. In developmental biology, organs that developed in the embryo in the same manner and from similar origins, such as from matching primord ...
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