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Functional Residual Capacity
Functional residual capacity (FRC) is the lung volume, volume of air present in the lungs at the end of passive Exhalation, expiration.Hopkins E, Sharma S. Physiology, Functional Residual Capacity. [Updated 2022 Jan 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK500007/ At FRC, the opposing elastic recoil forces of the lungs and chest wall are in equilibrium and there is no exertion by the thoracic diaphragm, diaphragm or other respiratory muscles. Measurement FRC is the sum of expiratory reserve volume (ERV) and residual volume (RV)Levitzky M.G. (2021). Alveolar ventilation. Levitzky M, & McDonough K, & Kaye A, & Hall S(Eds.), Clinical Physiology in Anesthetic Practice. McGraw Hill. https://accessanesthesiology.mhmedical.com/content.aspx?bookid=2979§ionid=249590087 and measures approximately 3000 mL in a 70 kg, average-sized male. It cannot be estimated through spirometry, sinc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Respiratory Disease
Respiratory diseases, or lung diseases, are pathological conditions affecting the organs and tissues that make gas exchange difficult in air-breathing animals. They include conditions of the respiratory tract including the trachea, bronchi, bronchioles, alveoli, pleurae, pleural cavity, the nerves and muscles of respiration. Respiratory diseases range from mild and self-limiting, such as the common cold, influenza, and pharyngitis to life-threatening diseases such as bacterial pneumonia, pulmonary embolism, tuberculosis, acute asthma, lung cancer, and severe acute respiratory syndromes, such as COVID-19. Respiratory diseases can be classified in many different ways, including by the organ or tissue involved, by the type and pattern of associated signs and symptoms, or by the cause of the disease. The study of respiratory disease is known as pulmonology. A physician who specializes in respiratory disease is known as a pulmonologist, a chest medicine specialist, a r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Respiratory Physiology
In physiology, respiration is the transport of oxygen from the outside environment to the cells within tissues, and the removal of carbon dioxide in the opposite direction to the environment by a respiratory system. The physiological definition of respiration differs from the biochemical definition, which refers to a metabolic process by which an organism obtains energy (in the form of ATP and NADPH) by oxidizing nutrients and releasing waste products. Although physiologic respiration is necessary to sustain cellular respiration and thus life in animals, the processes are distinct: cellular respiration takes place in individual cells of the organism, while physiologic respiration concerns the diffusion and transport of metabolites between the organism and the external environment. Exchange of gases in the lung occurs by ventilation and perfusion. Ventilation refers to the in-and-out movement of air of the lungs and perfusion is the circulation of blood in the pulmonary capillar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SNOMED CT
SNOMED CT or SNOMED Clinical Terms is a systematically organized computer-processable collection of medical terms providing codes, terms, synonyms and definitions used in clinical documentation and reporting. SNOMED CT is considered to be the most comprehensive, multilingual clinical healthcare terminology in the world. The primary purpose of SNOMED CT is to encode the meanings that are used in health information and to support the effective clinical recording of data with the aim of improving patient care. SNOMED CT provides the core general terminology for electronic health records. SNOMED CT comprehensive coverage includes: clinical findings, symptoms, diagnoses, procedures, body structures, organisms and other etiologies, substances, pharmaceuticals, devices and specimens. SNOMED CT is maintained and distributed by SNOMED International, an international non-profit standards development organization, located in London, UK. SNOMED International is the trading name of the Intern ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
LOINC
Logical Observation Identifiers Names and Codes (LOINC) is a database and universal standard for identifying medical laboratory observations. First developed in 1994, it was created and is maintained by the Regenstrief Institute, a US nonprofit medical research organization. LOINC was created in response to the demand for an electronic clinical care and management database and is publicly available at no cost. It is endorsed by the American Clinical Laboratory Association. Since its inception, the database has expanded to include not just medical laboratory code names but also nursing diagnosis, nursing interventions, outcomes classification, and patient care data sets. Function LOINC applies universal code names and identifiers to medical terminology related to electronic health records. The purpose is to assist in the electronic exchange and gathering of clinical results (such as laboratory tests, clinical observations, outcomes management and research). LOINC has two main part ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Total Lung Capacity
Lung volumes and lung capacities are measures of the volume of air in the lungs at different phases of the respiratory cycle. The average total lung capacity of an adult human male is about 6 litres of air. Tidal breathing is normal, resting breathing; the tidal volume is the volume of air that is inhaled or exhaled in only a single such breath. The average human respiratory rate is 30–60 breaths per minute at birth, decreasing to 12–20 breaths per minute in adults. Factors affecting volumes Several factors affect lung volumes; some can be controlled, and some cannot be controlled. Lung volumes vary with different people as follows: A person who is born and lives at sea level will develop a slightly smaller lung capacity than a person who spends their life at a high altitude. This is because the partial pressure of oxygen is lower at higher altitude which, as a result means that oxygen less readily diffuses into the bloodstream. In response to higher altitude, the body ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Compliance (physiology)
Compliance is the ability of a hollow organ (vessel) to distend and increase volume with increasing transmural pressure or the tendency of a hollow organ to resist recoil toward its original dimensions on application of a distending or compressing force. The reciprocal of compliance is elastance, a measure of the tendency of a hollow organ to recoil toward its original dimensions upon removal of a distending or compressing force. Blood vessels The terms elastance and compliance are of particular significance in cardiovascular physiology and respiratory physiology. In compliance, an increase in volume occurs in a vessel when the pressure in that vessel is increased. The tendency of the arteries and veins to stretch in response to pressure has a large effect on perfusion and blood pressure. This physically means that blood vessels with a higher compliance deform easier than lower compliance blood vessels under the same pressure and volume conditions. Venous compliance is approximate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emphysema
Emphysema is any air-filled enlargement in the body's tissues. Most commonly emphysema refers to the permanent enlargement of air spaces (alveoli) in the lungs, and is also known as pulmonary emphysema. Emphysema is a lower respiratory tract disease, characterised by enlarged air-filled spaces in the lungs, that can vary in size and may be very large. The spaces are caused by the breakdown of the Alveolar wall, walls of the Pulmonary alveolus, alveoli, which replace the spongy Parenchyma#Lungs, lung tissue. This reduces the total alveolar surface available for gas exchange leading to a reduction in oxygen supply for the blood. Emphysema usually affects the middle aged or Old age, older population because it takes time to develop with the effects of tobacco smoking and other risk factors. Alpha-1 antitrypsin deficiency is a genetic risk factor that may lead to the condition presenting earlier. When associated with significant airflow limitation, emphysema is a Chronic obstructive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Obstructive Lung Disease
Obstructive lung disease is a category of respiratory disease characterized by airway obstruction. Many obstructive diseases of the lung result from narrowing (obstruction) of the smaller bronchi and larger bronchioles, often because of excessive contraction of the smooth muscle itself. It is generally characterized by inflamed and easily collapsible airways, obstruction to airflow, problems exhaling, and frequent medical clinic visits and hospitalizations. Types of obstructive lung disease include asthma, bronchiectasis, bronchitis and chronic obstructive pulmonary disease (COPD). Although COPD shares similar characteristics with all other obstructive lung diseases, such as the signs of coughing and wheezing, they are distinct conditions in terms of disease onset, frequency of symptoms, and reversibility of airway obstruction. Cystic fibrosis is also sometimes included in obstructive pulmonary disease. Types Asthma Asthma is an obstructive lung disease where the bronchial tu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Restrictive Lung Disease
Restrictive lung diseases are a category of extrapulmonary, pleural, or parenchymal respiratory diseases that restrict lung expansion, resulting in a decreased lung volume, an increased work of breathing, and inadequate ventilation and/or oxygenation. Pulmonary function test demonstrates a decrease in the forced vital capacity. Presentation Due to the chronic nature of this disease, the leading symptom of restrictive lung disease is progressive exertional dyspnea. For acute on chronic cases, shortness of breath, cough, and respiratory failure are some of the more common signs. Causes Restrictive lung diseases may be due to specific causes which can be intrinsic to the parenchyma of the lung, or extrinsic to it. Intrinsic * Pneumoconiosis caused by long-term exposure to dusts, especially in mining. For example, Asbestosis. * Radiation fibrosis, usually from the radiation given for cancer treatment. * Certain drugs such as amiodarone, bleomycin and methotrexate. * As a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Body Plethysmography
A plethysmograph is an instrument for measuring changes in volume within an organ or whole body (usually resulting from fluctuations in the amount of blood or air it contains). The word is derived from the Greek "plethysmos" (increasing, enlarging, becoming full), and "graphein" (to write). Organs studied Lungs Pulmonary plethysmographs are commonly used to measure the functional residual capacity (FRC) of the lungs—the volume in the lungs when the muscles of respiration are relaxed—and total lung capacity. In a traditional plethysmograph (or "body box"), the test subject, or patient, is placed inside a sealed chamber the size of a small telephone booth with a single mouthpiece. At the end of normal expiration, the mouthpiece is closed. The patient is then asked to make an inspiratory effort. As the patient tries to inhale (a maneuver which looks and feels like panting), the lungs expand, decreasing pressure within the lungs and increasing lung volume. This, in turn, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lung Volume
Lung volumes and lung capacities are measures of the volume of air in the lungs at different phases of the respiratory cycle. The average total lung capacity of an adult human male is about 6 litres of air. Tidal breathing is normal, resting breathing; the tidal volume is the volume of air that is inhaled or exhaled in only a single such breath. The average human respiratory rate is 30–60 breaths per minute at birth, decreasing to 12–20 breaths per minute in adults. Factors affecting volumes Several factors affect lung volumes; some can be controlled, and some cannot be controlled. Lung volumes vary with different people as follows: A person who is born and lives at sea level will develop a slightly smaller lung capacity than a person who spends their life at a high altitude. This is because the partial pressure of oxygen is lower at higher altitude which, as a result means that oxygen less readily diffuses into the bloodstream. In response to higher altitude, the body's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
