Franklin Stahl
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Franklin Stahl
Franklin (Frank) William Stahl (born October 8, 1929) is an American molecular biologist and geneticist. With Matthew Meselson, Stahl conducted the famous Meselson-Stahl experiment showing that DNA is replicated by a semiconservative mechanism, meaning that each strand of the DNA serves as a template for production of a new strand. He is Emeritus Professor of Biology at the University of Oregon's Institute of Molecular Biology in Eugene, Oregon. Career Stahl, like his two older sisters, graduated from the public schools of Needham, a Boston suburb. In 1951, he was awarded an AB degree in biology from Harvard College, and matriculated in the biology department of the University of Rochester. His interest in genetics was cemented in 1952 by his introduction to bacterial viruses (phages) in a course taught by A. H. (Gus) Doermann at the Cold Spring Harbor Biological Laboratory. In 1956, he received a PhD in biology for his work with Doermann on the genetics of T4 phage. In 1955 ...
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Giuseppe Bertani
Giuseppe is the Italian form of the given name Joseph, from Latin Iōsēphus from Ancient Greek Ἰωσήφ (Iōsḗph), from Hebrew יוסף. It is the most common name in Italy and is unique (97%) to it. The feminine form of the name is Giuseppina. People with the given name Artists and musicians * Giuseppe Aldrovandini (1671–1707), Italian composer * Giuseppe Arcimboldo (1526 or 1527–1593), Italian painter * Giuseppe Belli (singer) (1732–1760), Italian castrato singer * Giuseppe Gioachino Belli (1791–1863), Italian poet * Giuseppe Castiglione (1829–1908) (1829–1908), Italian painter * Giuseppe Giordani (1751–1798), Italian composer, mainly of opera * Giuseppe Ottaviani (born 1978), Italian musician and disc jockey * Giuseppe Psaila (1891–1960), Maltese Art Nouveau architect * Giuseppe Sammartini (1695–1750), Italian composer and oboist * Giuseppe Sanmartino or Sammartino (1720–1793), Italian sculptor * Giuseppe Santomaso (1907–1990), Italian painter * ...
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Genetics (journal)
''Genetics'' is a monthly scientific journal publishing investigations bearing on heredity, genetics, biochemistry and molecular biology. Genetics is published by the Genetics Society of America. It has a delayed open access policy, and makes articles available online without a subscription after 12 months have elapsed since first publication. Since 2010, it is published online-only.http://www.councilscienceeditors.org/wp-content/uploads/v36n1p14-15_17.pdf George Harrison Shull George Harrison Shull (April 15, 1874 – September 28, 1954) was an eminent American plant geneticist and the younger brother of botanical illustrator and plant breeder J. Marion Shull. He was born on a farm in Clark County, Ohio, graduated fr ... was the founding editor of ''Genetics'' in 1916. Editors-in-Chief References External linksOfficial website Genetics journals Delayed open access journals English-language journals Publications established in 1916 Online-only journals {{ge ...
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Saccharomyces Cerevisiae
''Saccharomyces cerevisiae'' () (brewer's yeast or baker's yeast) is a species of yeast (single-celled fungus microorganisms). The species has been instrumental in winemaking, baking, and brewing since ancient times. It is believed to have been originally isolated from the skin of grapes. It is one of the most intensively studied eukaryotic model organisms in molecular biology, molecular and cell biology, much like ''Escherichia coli'' as the model bacteria, bacterium. It is the microorganism behind the most common type of fermentation (biochemistry), fermentation. ''S. cerevisiae'' cells are round to ovoid, 5–10 micrometre, μm in diameter. It reproduces by budding. Many proteins important in human biology were first discovered by studying their Homology (biology), homologs in yeast; these proteins include cell cycle proteins, signaling proteins, and protein-processing enzymes. ''S. cerevisiae'' is currently the only yeast cell known to have Berkeley body, Berkeley bo ...
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Lambda Phage
''Enterobacteria phage λ'' (lambda phage, coliphage λ, officially ''Escherichia virus Lambda'') is a bacterial virus, or bacteriophage, that infects the bacterial species ''Escherichia coli'' (''E. coli''). It was discovered by Esther Lederberg in 1950. The wild type of this virus has a temperate life cycle that allows it to either reside within the genome of its host through lysogeny or enter into a lytic phase, during which it kills and lyses the cell to produce offspring. Lambda strains, mutated at specific sites, are unable to lysogenize cells; instead, they grow and enter the lytic cycle after superinfecting an already lysogenized cell. The phage particle consists of a head (also known as a capsid), a tail, and tail fibers (see image of virus below). The head contains the phage's double-strand linear DNA genome. During infection, the phage particle recognizes and binds to its host, ''E. coli'', causing DNA in the head of the phage to be ejected through the tail into the ...
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Columbia, Missouri
Columbia is a city in the U.S. state of Missouri. It is the county seat of Boone County and home to the University of Missouri. Founded in 1821, it is the principal city of the five-county Columbia metropolitan area. It is Missouri's fourth most-populous and fastest growing city, with an estimated 126,254 residents in 2020. As a Midwestern college town, Columbia has a reputation for progressive politics, persuasive journalism, and public art. The tripartite establishment of Stephens College (1833), the University of Missouri (1839), and Columbia College (1851), which surround the city's Downtown to the east, south, and north, has made the city a center of learning. At its center is 8th Street (also known as the Avenue of the Columns), which connects Francis Quadrangle and Jesse Hall to the Boone County Courthouse and the City Hall. Originally an agricultural town, education is now Columbia's primary economic concern, with secondary interests in the healthcare, insurance ...
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University Of Missouri
The University of Missouri (Mizzou, MU, or Missouri) is a public university, public Land-grant university, land-grant research university in Columbia, Missouri. It is Missouri's largest university and the flagship of the four-campus University of Missouri System. MU was founded in 1839 and was the first public university west of the Mississippi River. It has been a member of the Association of American Universities since 1908 and is classified among "R1: Doctoral Universities – Very high research activity". To date, the University of Missouri alumni, faculty, and staff include 18 Rhodes Scholars, 19 Truman Scholars, 141 Fulbright Scholars, 7 Governors of Missouri, and 6 members of the U.S. Congress. Enrolling 31,401 students in 2021, it offers more than 300 degree programs in thirteen major academic divisions. Its well-known Missouri School of Journalism was founded by Walter Williams (journalist), Walter Williams in 1908 as the world's first journalism school; It publishes ...
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Francis Crick
Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical structure of the DNA molecule. Crick and Watson's paper in ''Nature'' in 1953 laid the groundwork for understanding DNA structure and functions. Together with Maurice Wilkins, they were jointly awarded the 1962 Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material". Crick was an important theoretical molecular biologist and played a crucial role in research related to revealing the helical structure of DNA. He is widely known for the use of the term " central dogma" to summarise the idea that once information is transferred from nucleic acids (DNA or RNA) to proteins, it cannot flow back to nucleic acids. In other words ...
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James Watson
James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper proposing the double helix structure of the DNA molecule. Watson, Crick and Maurice Wilkins were awarded the 1962 Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material". In subsequent years, it has been recognized that Watson and his colleagues did not properly attribute colleague Rosalind Franklin for her contributions to the discovery of the double helix structure. Watson earned degrees at the University of Chicago ( BS, 1947) and Indiana University (PhD, 1950). Following a post-doctoral year at the University of Copenhagen with Herman Kalckar and Ole Maaløe, Watson worked at the University of Cambridge's Cavendish Laboratory in England, where he first met his future collaborator Franc ...
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Escherichia Coli
''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escherichia'' that is commonly found in the lower intestine of warm-blooded organisms. Most ''E. coli'' strains are harmless, but some serotypes ( EPEC, ETEC etc.) can cause serious food poisoning in their hosts, and are occasionally responsible for food contamination incidents that prompt product recalls. Most strains do not cause disease in humans and are part of the normal microbiota of the gut; such strains are harmless or even beneficial to humans (although these strains tend to be less studied than the pathogenic ones). For example, some strains of ''E. coli'' benefit their hosts by producing vitamin K2 or by preventing the colonization of the intestine by pathogenic bacteria. These mutually beneficial relationships between ''E. col ...
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Charles Steinberg
Charles 'Charley' M. Steinberg (1932 September 17, 1999) was an immunobiologist and permanent member of the Basel Institute for Immunology. He was a former student of Max Delbrück. Notably he hosted Richard Feynman at Caltech when Feynman studied molecular biology, leading Feynman to remark that Charlie was “...the smartest guy I know”. He was instrumental in the discovery of V(D)J recombination, bacteriophage genetics as part of the phage group and co-discoverer of the amber-mutant of the T4 bacteriophage that led to the recognition of stop codons. The amber mutants discovered by Charles Steinberg in collaboration with Richard Epstein provided a unique opportunity to study the function of virtually all the genes of phage T4 that are required for growth of the phage under laboratory conditions. The circumstances under which the amber mutants were discovered was described by Edgar in a retrospective article.Edgar B. The genome of bacteriophage T4: an archeological dig. Gen ...
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Bacterial Genetics
Bacterial genetics is the subfield of genetics devoted to the study of bacterial genes. Bacterial genetics are subtly different from eukaryotic genetics, however bacteria still serve as a good model for animal genetic studies. One of the major distinctions between bacterial and eukaryotic genetics stems from the bacteria's lack of membrane-bound organelles (this is true of all prokaryotes. While it is a fact that there are prokaryotic organelles, they are never bound by a lipid membrane, but by a shell of proteins), necessitating protein synthesis occur in the cytoplasm. Like other organisms, bacteria also breed true and maintain their characteristics from generation to generation, yet at the same time, exhibit variations in particular properties in a small proportion of their progeny. Though heritability and variations in bacteria had been noticed from the early days of bacteriology, it was not realised then that bacteria too obey the laws of genetics. Even the existence of a ba ...
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