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Four Boxes Test
The four boxes test is a computer-based test used to measure reaction times. In the test, a black circle appears in one of four boxes on the screen, and the patient presses the corresponding key on the keyboard as quickly as possible. The next circle appears after 500 ms, until 52 circles have been exposed. The computer measures the time the subject takes to complete the test and the number of errors they make. The test has been used to measure long-term cognitive dysfunction in elderly people who have undergone an operation. When subjects had undergone anesthesia with different drugs, and were then tested using the Stroop Colour and Word Interference Test, the digit symbol substitution test and the four boxes test, recovery times varied both by anesthetic and by type of test. Other studies have shown that there is an association between postoperative cognitive dysfunction Postoperative cognitive dysfunction (POCD) is a decline in cognition, cognitive function (especially i ...
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The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, review articles ("seminars" and "reviews"), editorials, book reviews, correspondence, as well as news features and case reports. ''The Lancet'' has been owned by Elsevier since 1991, and its editor-in-chief since 1995 has been Richard Horton. The journal has editorial offices in London, New York City, and Beijing. History ''The Lancet'' was founded in 1823 by Thomas Wakley, an English surgeon who named it after the surgical instrument called a lancet (scalpel). Members of the Wakley family retained editorship of the journal until 1908. In 1921, ''The Lancet'' was acquired by Hodder & Stoughton. Elsevier acquired ''The Lancet'' from Hodder & Stoughton in 1991. Impact According to the ''Journal Citation Reports'', the journal has a 202 ...
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Stroop Effect
---- ---- Naming the font color of a printed word is an easier and quicker task if word meaning and font color are congruent. If two words are both printed in red, the average time to say "red" in response to the written word "green" is greater than the time to say "red" in response to the written word "mouse". In psychology, the Stroop effect is the delay in reaction time between congruent and incongruent stimuli. The effect has been used to create a psychological test (the Stroop test) that is widely used in clinical practice and investigation. A basic task that demonstrates this effect occurs when there is a mismatch between the name of a color (e.g., "blue", "green", or "red") and the color it is printed on (i.e., the word "red" printed in blue ink instead of red ink). When asked to name the color of the word it takes longer and is more prone to errors when the color of the ink does not match the name of the color. The effect is named after John Ridley Stroop, who ...
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Digit Symbol Substitution Test
Digit symbol substitution test (DSST) is a neuropsychological test sensitive to brain damage, dementia, age and depression. The test is not sensitive to the location of brain-damage (except for damage comprising part of the visual field). It consists of (e.g. nine) digit-symbol pairs (e.g. 1/-,2/┴ ... 7/Λ,8/X,9/=) followed by a list of digits. Under each digit the subject should write down the corresponding symbol as fast as possible. The number of correct symbols within the allowed time (e.g. 90 or 120 sec) is measured. The DSST contained in the Wechsler Adult Intelligence Scale is called 'Digit Symbol' (WAIS-R), 'Digit-Symbol-Coding' (WAIS-III), or most recently, 'Coding' (WAIS-IV). Based on The Boston Process Approach to assessment, in order to examine the role of memory in Digit-Symbol-Coding performance, WAIS-III (but not WAIS-IV) contains an optional implicit learning test: after the Digit Symbol-Coding test paired and free recall of the symbols is assessed. The National ...
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Postoperative Cognitive Dysfunction
Postoperative cognitive dysfunction (POCD) is a decline in cognition, cognitive function (especially in memory and executive functions) that may last from 1–12 months after surgery, or longer. In some cases, this disorder may persist for several years after major surgery. POCD is distinct from emergence delirium. Its causes are under investigation and occurs commonly in older patients and those with pre-existing cognitive impairment. The causes of POCD are not understood. It does not appear to be caused by lack of oxygen or impaired blood flow to the brain and is equally likely under regional and general anesthesia. It may be mediated by the body's inflammation, inflammatory response to surgery. Causes The body's inflammation, inflammatory response to surgery likely plays an important role, at least in elderly patients. Various research initiatives during recent years have evaluated whether actions taken before, during and after surgery can lessen the possible deleterious effects ...
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