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Fluoroethyl Fluoroacetate
Fluoroethyl fluoroacetate is the fluoroacetate ester of 2-fluoroethanol. It is two times more toxic than methyl fluoroacetate. See also *Methyl fluoroacetate * Fluoroacetic acid * Sodium fluoroacetate *Fluoroacetamide Fluoroacetamide is an organic compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group. it is a metabolic poison which disrupts the citric acid cycle and was used as a rodenticide.MATSUMURA F, O'BRIEN RD. A COMPAR ... * 2-Fluoroethanol References Convulsants Fluoroacetates Chemical weapons Poisons Fluoroethyl esters {{Ester-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fluoroacetate
Fluoroacetate may refer to: * Fluoroacetic acid * Sodium fluoroacetate Sodium fluoroacetate is an organofluorine chemical compound with the formula FCH2CO2Na. This colourless salt has a taste similar to that of sodium chloride and is used as a rodenticide. History and production The effectiveness of sodium fluoroa ... {{Short pages monitor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ester
In chemistry, an ester is a compound derived from an oxoacid (organic or inorganic) in which at least one hydroxyl group () is replaced by an alkoxy group (), as in the substitution reaction of a carboxylic acid and an alcohol. Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Phosphoesters form the backbone of DNA molecules. Nitrate esters, such as nitroglycerin, are known for their explosive properties. '' Nomenclature Etymology Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methyl Fluoroacetate
Methyl fluoroacetate (MFA) is an extremely toxic methyl ester of fluoroacetic acid. It is a colorless, odorless liquid at room temperature. It is used as a laboratory chemical and as a rodenticide. Because of its extreme toxicity, MFA was studied for potential use as a chemical weapon. The general population is not likely to be exposed to methyl fluoroacetate. People who use MFA for work, however, can breathe in or have direct skin contact with the substance.National Center for Biotechnology Information. PubChem Database. Methyl fluoroacetate, CID=9959, https://pubchem.ncbi.nlm.nih.gov/compound/Methyl-fluoroacetate (accessed on Mar. 20, 2020) History MFA was first synthesized in 1896 by the Belgian chemist Swart by reacting methyl iodoacetate with silver fluoride. It can also be synthesized by reacting methyl chloroacetate with potassium fluoride Because of its toxicity, MFA was studied for potential use as a chemical weapon during World War II. It was considered a good water po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methyl Fluoroacetate
Methyl fluoroacetate (MFA) is an extremely toxic methyl ester of fluoroacetic acid. It is a colorless, odorless liquid at room temperature. It is used as a laboratory chemical and as a rodenticide. Because of its extreme toxicity, MFA was studied for potential use as a chemical weapon. The general population is not likely to be exposed to methyl fluoroacetate. People who use MFA for work, however, can breathe in or have direct skin contact with the substance.National Center for Biotechnology Information. PubChem Database. Methyl fluoroacetate, CID=9959, https://pubchem.ncbi.nlm.nih.gov/compound/Methyl-fluoroacetate (accessed on Mar. 20, 2020) History MFA was first synthesized in 1896 by the Belgian chemist Swart by reacting methyl iodoacetate with silver fluoride. It can also be synthesized by reacting methyl chloroacetate with potassium fluoride Because of its toxicity, MFA was studied for potential use as a chemical weapon during World War II. It was considered a good water po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fluoroacetic Acid
Fluoroacetic acid is a organofluorine compound with formula CH2FCO2H. It is a colorless solid that is noted for its relatively high toxicity. The conjugate base, fluoroacetate occurs naturally in at least 40 plants in Australia, Brazil, and Africa. It is one of only five known organic fluorine-containing natural products. Toxicity Fluoroacetic acid is a harmful metabolite of some fluorine-containing drugs (median lethal dose, LD50 = 10 mg/kg in humans). The most common metabolic sources of fluoroacetic acid are fluoroamines and fluoroethers. Fluoroacetic acid can disrupt the Krebs cycle. In contrast with monofluoroacetic acid, difluoroacetic acid and trifluoroacetic acid are far less toxic. Its pKa is 2.66, in contrast to 1.24 and 0.23 for the respective di- and trifluorinated acids. Uses Fluoroacetic acid is used to manufacture pesticides especially rodenticides (see sodium fluoroacetate Sodium fluoroacetate is an organofluorine chemical compound with the formula FCH2CO2Na ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Fluoroacetate
Sodium fluoroacetate is an organofluorine chemical compound with the formula FCH2CO2Na. This colourless salt has a taste similar to that of sodium chloride and is used as a rodenticide. History and production The effectiveness of sodium fluoroacetate as a rodenticide was reported in 1942. The name "1080" refers to the catalogue number of the poison, which became its brand name. The salt is synthesized by treating sodium chloroacetate with potassium fluoride. Both sodium and potassium salts are derivatives of fluoroacetic acid. Natural occurrence Fluoroacetate occurs naturally in at least 40 plants in Australia, Brazil, and Africa. It is one of only five known organic fluorine-containing natural products. Fluoroacetate occurrence in ''Gastrolobium'' species ''Gastrolobium'' is a genus of flowering plants in the family Fabaceae. This genus consists of over 100 species, and all but two are native to the southwest region of Western Australia, where they are known as "poison peas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fluoroacetamide
Fluoroacetamide is an organic compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group. it is a metabolic poison which disrupts the citric acid cycle and was used as a rodenticide.MATSUMURA F, O'BRIEN RD. A COMPARATIVE STUDY OF THE MODES OF ACTION OF FLUOROACETAMIDE AND FLUOROACETATE IN THE MOUSE AND AMERICAN COCKROACH. ''Biochem Pharmacol''. 1963 Oct;12:1201-5. See also * Sodium fluoroacetate Sodium fluoroacetate is an organofluorine chemical compound with the formula FCH2CO2Na. This colourless salt has a taste similar to that of sodium chloride and is used as a rodenticide. History and production The effectiveness of sodium fluoroa ... References Rodenticides Acetamides Organofluorides Respiratory toxins {{organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Convulsants
A convulsant is a drug which induces convulsions and/or epileptic seizures, the opposite of an anticonvulsant. These drugs generally act as stimulants at low doses, but are not used for this purpose due to the risk of convulsions and consequent excitotoxicity. Most convulsants are antagonists (or inverse agonists) at either the GABAA or glycine receptors, or ionotropic glutamate receptor agonists. Many other drugs may cause convulsions as a side effect at high doses (e.g. bupropion, tramadol, pethidine, dextropropoxyphene, clomipramine) but only drugs whose primary action is to cause convulsions are known as convulsants. Nerve agents such as sarin, which were developed as chemical weapons, produce convulsions as a major part of their toxidrome, but also produce a number of other effects in the body and are usually classified separately. Dieldrin which was developed as an insecticide blocks chloride influx into the neurons causing hyperexcitability of the CNS and convulsions. The I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fluoroacetates
Fluoroacetic acid is a organofluorine compound with formula CH2FCO2H. It is a colorless solid that is noted for its relatively high toxicity. The conjugate base, fluoroacetate occurs naturally in at least 40 plants in Australia, Brazil, and Africa. It is one of only five known organic fluorine-containing natural products. Toxicity Fluoroacetic acid is a harmful metabolite of some fluorine-containing drugs (median lethal dose, LD50 = 10 mg/kg in humans). The most common metabolic sources of fluoroacetic acid are fluoroamines and fluoroethers. Fluoroacetic acid can disrupt the Krebs cycle. In contrast with monofluoroacetic acid, difluoroacetic acid and trifluoroacetic acid are far less toxic. Its pKa is 2.66, in contrast to 1.24 and 0.23 for the respective di- and trifluorinated acids. Uses Fluoroacetic acid is used to manufacture pesticides especially rodenticides (see sodium fluoroacetate Sodium fluoroacetate is an organofluorine chemical compound with the formula FCH2CO ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Weapons
A chemical weapon (CW) is a specialized Ammunition, munition that uses chemicals chemical engineering, formulated to inflict death or harm on humans. According to the Organisation for the Prohibition of Chemical Weapons (OPCW), this can be any chemical compound intended as a weapon "or its Precursor (chemistry), precursor that can cause death, injury, temporary incapacitation or sensory irritation through its chemical action. Munitions or other delivery devices designed to deliver chemical weapons, whether filled or unfilled, are also considered weapons themselves." Chemical weapons are classified as weapons of mass destruction (WMD), though they are distinct from nuclear weapons, biological warfare, biological weapons, and radiological weapons. All may be used in warfare and are known by the military acronym NBC (for nuclear, biological, and chemical warfare). Weapons of mass destruction are distinct from conventional weapons, which are primarily effective due to their explos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
