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Flagship Pioneering
Flagship Pioneering is an American life sciences venture capital company based in Cambridge, Massachusetts that invests in biotechnology, life sciences, health and sustainability companies. Portfolio companies include Moderna, Indigo Agriculture, Inari Agriculture and Novomer. The firm both funds and incubates companies. History The company was founded in Cambridge in 1999 by Noubar Afeyan and Ed Kania under the name NewcoGen (short for "new company generation"), but later changed its name to Flagship Ventures, and again in 2016 to Flagship Pioneering. In late 2010, Flagship formed Moderna, which focuses on drug discovery, drug development, and vaccine technologies based exclusively on messenger RNA (mRNA) technology, and which is famous for its COVID-19 vaccine. In 2013, Flagship helped fund the creation of Editas Medicine to use CRISPR gene editing for the development of pharmacological therapies, originally based on the genetic engineering protein Cas9. Editas was f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Private Company
A privately held company (or simply a private company) is a company whose shares and related rights or obligations are not offered for public subscription or publicly negotiated in the respective listed markets, but rather the company's stock is offered, owned, traded, exchanged privately, or Over-the-counter (finance), over-the-counter. In the case of a closed corporation, there are a relatively small number of shareholders or company members. Related terms are closely-held corporation, unquoted company, and unlisted company. Though less visible than their public company, publicly traded counterparts, private companies have major importance in the world's economy. In 2008, the 441 list of largest private non-governmental companies by revenue, largest private companies in the United States accounted for ($1.8 trillion) in revenues and employed 6.2 million people, according to ''Forbes''. In 2005, using a substantially smaller pool size (22.7%) for comparison, the 339 companies on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CRISPR Gene Editing
CRISPR gene editing (pronounced "crisper") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified. It is based on a simplified version of the bacterial CRISPR-Cas9 antiviral defense system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing existing genes to be removed and/or new ones added ''in vivo''. The technique is considered highly significant in biotechnology and medicine as it enables editing genomes ''in vivo'' very precisely, cheaply, and easily. It can be used in the creation of new medicines, agricultural products, and genetically modified organisms, or as a means of controlling pathogens and pests. It also has possibilities in the treatment of inherited genetic diseases as well as diseases arising from somatic mutations such as cancer. However, its use in human germline genetic modification is highly controve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Venture Capital Firms Of The United States
Venture may refer to: Arts and entertainment Music *The Ventures, an American instrumental rock band formed in 1958 *"A Venture", 1971 song by the band Yes *''Venture'', a 2010 EP by AJR Games * ''Venture'' (video game), a 1981 arcade game *''Venture'', a strategic card game by Sid Sackson Film * SS ''Venture'', a ship in ''King Kong'' and its 2005 remake * SS ''Venture'', an InGen-owned ship featured in '' The Lost World: Jurassic Park'' Other uses * ''Venture'' (TV series), a Canadian business television show Magazines * ''Venture Science Fiction'', defunct US science fiction magazine * ''Venture'' (magazine), a management magazine Business * Business venture * Venture (department store), a defunct discount department store operating across Australia * Venture Corporation, a Singapore firm * Venture Stores, a former retail chain Transportation * Chevrolet Venture, a General Motors minivan * Yamaha Venture, Yamaha touring motorcycles * Siemens Venture, fam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stat (website)
Stat (stylized STAT, sometimes also called Stat News) is an American health-oriented news website launched on November 4, 2015, by John W. Henry, the owner of ''The Boston Globe''. It is produced by Boston Globe Media and is headquartered in the ''Globe''s own building in Boston. Its executive editor is Rick Berke, who formerly worked at both ''The New York Times'' and ''Politico''. According to Kelsey Sutton of ''Politico'', the website is Henry's "biggest and most ambitious standalone site yet". The site's name comes from the term "stat", short for '' statim'', or "immediately"—a term that has long been used in medical contexts. As of February 2016, it had 45 staff members. Impact Notable stories Stat has broken include one about Robert Califf's research, published after then–President of the United States Barack Obama announced he would be his nominee to lead the Food and Drug Administration. The site also uncovered claims made by a vitamin company to which President Donal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polaris Partners
Polaris Partners is a venture capital firm active in the field of healthcare and biotechnology companies. The company has offices in Boston, Massachusetts, New York, NY and San Francisco, California. History Polaris Partners was founded in 1996 by Jon Flint, Terry McGuire, Steve Arnold. The firm has over $5 billion in committed capital and is now making investments through its tenth fund. The current managing partners are Brian Chee, Amy Schulman, and Darren Carroll. Polaris Partners also has two affiliate funds. Polaris Growth Fund targets investments in profitable, founder-owned technology companies and is led by managing partners Bryce Youngren and Dan Lombard. Polaris Innovation Fund focuses on the commercial and therapeutic potential of early-stage academic research and is led by managing partners Amy Schulman and Ellie McGuire. See alsoPolaris Growth Fund [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New Enterprise Associates
New Enterprise Associates (NEA) is an American-based venture capital firm. NEA focuses investment stages ranging from seed stage through growth stage across an array of industry sectors. With ~$25 billion in committed capital, NEA is one of the world's largest venture capital firms.NEA - History (Company Website)New Enterprise Associates Closes $2.6 Billion In One Of Largest Venture Funds Ever Forbes, July, 2012 Description The firm is headquartered in[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Simon & Schuster
Simon & Schuster () is an American publishing company and a subsidiary of Paramount Global. It was founded in New York City on January 2, 1924 by Richard L. Simon and M. Lincoln Schuster. As of 2016, Simon & Schuster was the third largest publisher in the United States, publishing 2,000 titles annually under 35 different imprints. History Early years In 1924, Richard Simon's aunt, a crossword puzzle enthusiast, asked whether there was a book of ''New York World'' crossword puzzles, which were very popular at the time. After discovering that none had been published, Simon and Max Schuster decided to launch a company to exploit the opportunity.Frederick Lewis Allen, ''Only Yesterday: An Informal History of the 1920s'', p. 165. . At the time, Simon was a piano salesman and Schuster was editor of an automotive trade magazine. They pooled , equivalent to $ today, to start a company that published crossword puzzles. The new publishing house used "fad" publishing to publish bo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Code Breaker
''The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race'' is a non-fiction book authored by American historian and journalist Walter Isaacson. Published in March 2021 by Simon & Schuster, it is a biography of Jennifer Doudna, the winner of the 2020 Nobel Prize in Chemistry for her work on the CRISPR system of gene editing. The book debuted at number one on ''The New York Times'' nonfiction best-seller list for the week ending March 13, 2021. Promotion On March 22, 2021, Isaacson appeared on ''The Late Show with Stephen Colbert'' to discuss the book. Reception In its starred review, ''Kirkus Reviews'' called it a "vital book about the next big thing in science—and yet another top-notch biography from Isaacson." ''Publishers Weekly'' called it a "gripping account of a great scientific advancement and of the dedicated scientists who realized it." References External links The Code Breakerat the Simon & Schuster websiteCRISPR Scientist's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize In Chemistry
) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "MDCCCXXXIII" above, followed by (smaller) "OB•" then "MDCCCXCVI" below. , awarded_for = Outstanding contributions in chemistry , presenter = Royal Swedish Academy of Sciences , location = Stockholm, Sweden , reward = 9 million SEK (2017) , year = 1901 , holder = Carolyn R. Bertozzi, Morten P. Meldal and Karl Barry Sharpless (2022) , most_awards = Frederick Sanger and Karl Barry Sharpless (2) , website nobelprize.org, previous = 2021 , year2=2022, main=2022, next=2023 The Nobel Prize in Chemistry is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David R
David (; , "beloved one") (traditional spelling), , ''Dāwūd''; grc-koi, Δαυΐδ, Dauíd; la, Davidus, David; gez , ዳዊት, ''Dawit''; xcl, Դաւիթ, ''Dawitʿ''; cu, Давíдъ, ''Davidŭ''; possibly meaning "beloved one". was, according to the Hebrew Bible, the third king of the United Kingdom of Israel. In the Books of Samuel, he is described as a young shepherd and harpist who gains fame by slaying Goliath, a champion of the Philistines, in southern Canaan. David becomes a favourite of Saul, the first king of Israel; he also forges a notably close friendship with Jonathan, a son of Saul. However, under the paranoia that David is seeking to usurp the throne, Saul attempts to kill David, forcing the latter to go into hiding and effectively operate as a fugitive for several years. After Saul and Jonathan are both killed in battle against the Philistines, a 30-year-old David is anointed king over all of Israel and Judah. Following his rise to power, David ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
George Church (geneticist)
George McDonald Church (born August 28, 1954) is an American geneticist, molecular engineer, chemist, and a serial entrepreneur who is widely regarded as the "Founding Father of Genomics", and a pioneer in personal genomics and synthetic biology. He is the Robert Winthrop Professor of Genetics at Harvard Medical School, Professor of Health Sciences and Technology at Harvard University and Massachusetts Institute of Technology, and a founding member of the Wyss Institute for Biologically Inspired Engineering at Harvard. Through his Harvard lab Church has co-founded around 50 biotech companies pushing the boundaries of innovation in the world of life sciences and making his lab as the hotbed of biotech startup activity in Boston.https://arep.med.harvard.edu/pdf/DeFrancesco_gclab_2019.pdf In 2018, the Church lab at Harvard made a record by spinning off 16 biotech companies in one year. The Church lab works on research projects that are distributed in diverse areas of modern biol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jennifer Doudna
Jennifer Anne Doudna (; born February 19, 1964) is an American biochemist who has done pioneering work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. Doudna was one of the first women to share a Nobel in the sciences. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editing." She is the Li Ka Shing Chancellor's Chair Professor in the Department of Chemistry and the Department of Molecular and Cell Biology at the University of California, Berkeley. She has been an investigator with the Howard Hughes Medical Institute since 1997. She graduated from Pomona College in 1985 and earned a Ph.D. from Harvard Medical School in 1989. Apart from her professorship at Berkeley, she is also president and chair of the board of the Innovative Genomics Institute, a faculty scientist at Lawrence Berkeley National Laboratory, a senior investigator at the Gladstone Institute ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
