First Flight (medical Research Horse)
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First Flight (medical Research Horse)
First Flight was a thoroughbred horse used in the production of the first botulism antitoxin. The horse was used as a research animal between 1978 and 1993 to produce antitoxin for military and civilian personnel. Until the 1990s, serum derived from First Flight was the only source of the antitoxin in the United States. Background First Flight was originally bred as a racehorse, but there are no records of him competing in a race in the National Sporting Library & Museum. He was trained to serve as a caisson horse during military funerals at Arlington National Cemetery. However, the horse was skittish around crowds and prone to bolting. Antitoxin production Botulinum toxin is a highly potent neurotoxin produced by the bacteria Clostridium botulinum, causing paralysis and often leading to death if untreated. There are three naturally occurring subtypes of botulism toxin; however, the four other known subtypes could be weaponised as bio-agents. Horses have been used in the p ...
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Fort Detrick
Fort Detrick () is a United States Army Futures Command installation located in Frederick, Maryland. Historically, Fort Detrick was the center of the U.S. biological weapons program from 1943 to 1969. Since the discontinuation of that program, it has hosted most elements of the United States biological defense program. As of the early 2010s, Fort Detrick's campus supports a multi-governmental community that conducts biomedical research and development, medical materiel management, global medical communications and the study of foreign plant pathogens. The lab is known to research pathogens such as Ebola and smallpox. It is home to the U.S. Army Medical Research and Development Command (USAMRDC), with its bio-defense agency, the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). It also hosts the National Cancer Institute-Frederick (NCI-Frederick) and is home to the National Interagency Confederation for Biological Research (NICBR) and National Interagen ...
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Gulf War
The Gulf War was a 1990–1991 armed campaign waged by a 35-country military coalition in response to the Iraqi invasion of Kuwait. Spearheaded by the United States, the coalition's efforts against Iraq were carried out in two key phases: Operation Desert Shield, which marked the military buildup from August 1990 to January 1991; and Operation Desert Storm, which began with the aerial bombing campaign against Iraq on 17 January 1991 and came to a close with the American-led Liberation of Kuwait on 28 February 1991. On 2 August 1990, Iraq invaded the neighbouring State of Kuwait and had fully occupied the country within two days. Initially, Iraq ran the occupied territory under a puppet government known as the "Republic of Kuwait" before proceeding with an outright annexation in which Kuwaiti sovereign territory was split, with the "Saddamiyat al-Mitla' District" being carved out of the country's northern portion and the "Kuwait Governorate" covering the rest. Varying spe ...
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Individual Horses
An individual is that which exists as a distinct entity. Individuality (or self-hood) is the state or quality of being an individual; particularly (in the case of humans) of being a person unique from other people and possessing one's own needs or goals, rights and responsibilities. The concept of an individual features in diverse fields, including biology, law, and philosophy. Etymology From the 15th century and earlier (and also today within the fields of statistics and metaphysics) ''individual'' meant " indivisible", typically describing any numerically singular thing, but sometimes meaning "a person". From the 17th century on, ''individual'' has indicated separateness, as in individualism. Law Although individuality and individualism are commonly considered to mature with age/time and experience/wealth, a sane adult human being is usually considered by the state as an "individual person" in law, even if the person denies individual culpability ("I followed instr ...
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Botulism
Botulism is a rare and potentially fatal illness caused by a toxin produced by the bacterium ''Clostridium botulinum''. The disease begins with weakness, blurred vision, feeling tired, and trouble speaking. This may then be followed by weakness of the arms, chest muscles, and legs. Vomiting, swelling of the abdomen, and diarrhea may also occur. The disease does not usually affect consciousness or cause a fever. Botulism can be spread in several ways. The bacterial spores which cause it are common in both soil and water. They produce the botulinum toxin when exposed to low oxygen levels and certain temperatures. Foodborne botulism happens when food containing the toxin is eaten. Infant botulism happens when the bacteria develops in the intestines and releases the toxin. This typically only occurs in children less than six months old, as protective mechanisms develop after that time. Wound botulism is found most often among those who inject street drugs. In this situation, spore ...
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Animal Testing In The United States
Animals are multicellular, eukaryotic organisms in the biological kingdom Animalia. With few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and go through an ontogenetic stage in which their body consists of a hollow sphere of cells, the blastula, during embryonic development. Over 1.5 million living animal species have been described—of which around 1 million are insects—but it has been estimated there are over 7 million animal species in total. Animals range in length from to . They have complex interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology. Most living animal species are in Bilateria, a clade whose members have a bilaterally symmetric body plan. The Bilateria include the protostomes, containing animals such as nematodes, arthropods, flatworms, annelids and molluscs, and the deuterostomes, containing the echinoderms a ...
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1999 Animal Deaths
File:1999 Events Collage.png, From left, clockwise: The funeral procession of King Hussein of Jordan in Amman; the 1999 İzmit earthquake kills over 17,000 people in Turkey; the Columbine High School massacre, one of the first major school shootings in the United States; the Year 2000 problem ("Y2K"), perceived as a major concern in the lead-up to the year 2000; the Millennium Dome opens in London; online music downloading platform Napster is launched, soon a source of online piracy; NASA loses both the Mars Climate Orbiter and the Mars Polar Lander; a destroyed T-55 tank near Prizren during the Kosovo War., 300x300px, thumb rect 0 0 200 200 Death and state funeral of King Hussein rect 200 0 400 200 1999 İzmit earthquake rect 400 0 600 200 Columbine High School massacre rect 0 200 300 400 Kosovo War rect 300 200 600 400 Year 2000 problem rect 0 400 200 600 Mars Climate Orbiter rect 200 400 400 600 Napster rect 400 400 600 600 Millennium Dome 1999 was designated as the Interna ...
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Individual Animals In The United States
An individual is that which exists as a distinct entity. Individuality (or self-hood) is the state or quality of being an individual; particularly (in the case of humans) of being a person unique from other people and possessing one's own needs or goals, rights and responsibilities. The concept of an individual features in diverse fields, including biology, law, and philosophy. Etymology From the 15th century and earlier (and also today within the fields of statistics and metaphysics) ''individual'' meant " indivisible", typically describing any numerically singular thing, but sometimes meaning "a person". From the 17th century on, ''individual'' has indicated separateness, as in individualism. Law Although individuality and individualism are commonly considered to mature with age/time and experience/wealth, a sane adult human being is usually considered by the state as an "individual person" in law, even if the person denies individual culpability ("I followed instruct ...
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Heptavalent Botulism Antitoxin
The Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G) - (Equine) – BAT, made by Emergent BioSolutions Canada Inc. (formerly Cangene Corporation) – is a licensed, commercially available botulism anti-toxin that effectively neutralizes all seven known botulinum nerve toxin serotypes (types A, B, C, D, E, F and G). It is indicated for sporadic cases of life-threatening botulism and is also stockpiled for the eventuality of botulinum nerve toxins being used in a future bioterrorist attack. BAT was first approved in 2010 by the Centers for Disease Control for the indication of treating naturally occurring non-infant botulism on an investigational basis, replacing two earlier products. It was then licensed for commercial marketing by the United States FDA in 2013. History Development and domestic contracts BAT (formerly known as HBAT) was developed from equine (horse) plasma at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). The main funding strea ...
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Lead (tack)
A lead, lead line, lead rope (US) or head collar rope (UK), is used to lead an animal such as a horse. Usually, it is attached to a halter. The lead may be integral to the halter or, more often, separate. When separate, it is attached to the halter with a heavy clip or snap so that it can be added or removed as needed. A related term, lead shank or lead chain refers to a lead line with a chain attached that is used in a variety of ways to safely control possibly difficult or dangerous horses if they will not respond to a regular lead. Variations A lead can be made from a variety of materials, including cotton, horsehair (woven or braided hair, usually from a horse's tail), leather, nylon or other synthetic materials. Lead ropes, as the name implies, are round and made of various types of rope, usually between 5/8 and 3/4 inch (about 2 cm) in diameter.http://www.sstack.com Halters and leads at Schneider's Saddlery Co. Lead lines are usually flat webbing or le ...
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Halter
A halter or headcollar is headgear that is used to lead or tie up livestock and, occasionally, other animals; it fits behind the ears (behind the poll), and around the muzzle. To handle the animal, usually a lead rope is attached. On smaller animals, such as dogs, a leash is attached to the halter. History Halters may be as old as the early domestication of animals, and their history is not as well studied as that of the bridle or hackamore. The word "halter" derives from the Germanic words meaning "that by which anything is held." Uses A halter is used to lead and tie up an animal.Loch, Wayne. "Haltering and Tying Horses." Department of Animal Sciences, University of Missouri Extension. G28 ...
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National Museum Of American History
The National Museum of American History: Kenneth E. Behring Center collects, preserves, and displays the heritage of the United States in the areas of social, political, cultural, scientific, and military history. Among the items on display is the original Star-Spangled Banner (flag), Star-Spangled Banner. The museum is part of the Smithsonian Institution and located on the National Mall at 14th Street (Washington, D.C.), 14th Street and Constitution Avenue NW in Washington, D.C. History The museum opened in 1964 as the Museum of History and Technology. It was one of the last structures designed by the renowned architectural firm McKim Mead & White. In 1980, the museum was renamed the National Museum of American History to represent its mission of the collection, care, study, and interpretation of objects that reflect the experience of the American people. The museum site had previously held two Temporary buildings of the National Mall, temporary war buildings constructed in 194 ...
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