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FightAIDS@Home
FightAIDS@Home ("Fight AIDS at home") is a volunteer computing project operated by the Olson Laboratory at The Scripps Research Institute. It runs on internet-connected home computers, and since July 2013 also runs on Android smartphones and tablets. It aims to use biomedical software simulation techniques to search for ways to cure or prevent the spread of HIV/AIDS. Methods Olson's target is HIV protease, a key molecular machine of the virus that when blocked stops it from maturing. These blockers, known as "protease inhibitors", are thus a way of avoiding the onset of AIDS and prolonging life. The Olson Laboratory is using computational methods to identify new candidate drugs that have the right shape and chemical characteristics to block HIV protease. This general approach is called structure-based drug design, and according to the National Institutes of Health's National Institute of General Medical Sciences, it has already had a dramatic effect on the lives of people living w ...
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World Community Grid
World Community Grid (WCG) is an effort to create the world's largest volunteer computing platform to tackle scientific research that benefits humanity. Launched on November 16, 2004, with proprietary Grid MP client from United Devices and adding support for Berkeley Open Infrastructure for Network Computing (BOINC) in 2005, World Community Grid eventually discontinued the Grid MP client and consolidated on the BOINC platform in 2008. In September 2021, it was announced that IBM transferred ownership to the Krembil Research Institute of University Health Network in Toronto, Ontario. World Community Grid utilizes unused processing power of consumer devices (PCs, Laptops, Android Smartphones, etc.) to analyse data created by the research groups that participate in the grid. WCG projects have analysed data related to the human genome, the human microbiome, HIV, dengue, muscular dystrophy, cancer, influenza, Ebola, Zika virus, virtual screening, rice crop yields, clean energy, water ...
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FightAIDS@home
FightAIDS@Home ("Fight AIDS at home") is a volunteer computing project operated by the Olson Laboratory at The Scripps Research Institute. It runs on internet-connected home computers, and since July 2013 also runs on Android smartphones and tablets. It aims to use biomedical software simulation techniques to search for ways to cure or prevent the spread of HIV/AIDS. Methods Olson's target is HIV protease, a key molecular machine of the virus that when blocked stops it from maturing. These blockers, known as "protease inhibitors", are thus a way of avoiding the onset of AIDS and prolonging life. The Olson Laboratory is using computational methods to identify new candidate drugs that have the right shape and chemical characteristics to block HIV protease. This general approach is called structure-based drug design, and according to the National Institutes of Health's National Institute of General Medical Sciences, it has already had a dramatic effect on the lives of people living w ...
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List Of Volunteer Computing Projects
This is a comprehensive list of volunteer computing projects; a type of distributed computing where volunteers donate computing time to specific causes. The donated computing power comes from idle CPUs and GPUs in personal computers, video game consoles and Android devices. Each project seeks to utilize the computing power of many internet connected devices to solve problems and perform tedious, repetitive research in a very cost effective manner. Active projects Completed projects See also * List of grid computing projects * List of citizen science projects * List of crowdsourcing projects * List of free and open-source Android applications This is a list of notable applications (''apps'') that run on the Android platform which meet guidelines for free software and open-source software. Advertisement blocking Web browsers Office Suites and synchronisation Co ... * List of Berkeley Open Infrastructure for Network Computing (BOINC) projects ...
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AutoDock
AutoDock is a molecular modeling simulation software. It is especially effective for protein-ligand docking. AutoDock 4 is available under the GNU General Public License. AutoDock is one of the most cited docking software applications in the research community. It is used by the FightAIDS@Home and OpenPandemics - COVID-19 projects run at World Community Grid, to search for antivirals against HIV/AIDS and COVID-19. In February 2007, a search of the ISI Citation Index showed more than 1,100 publications had been cited using the primary AutoDock method papers. As of 2009, this number surpassed 1,200. AutoDock Vina is a successor of AutoDock, significantly improved in terms of accuracy and performance. It is available under the Apache license. Both AutoDock and Vina are currently maintained by Scripps Research, specifically the Center for Computational Structural Biology (CCSB) led by Dr. Arthur J. Olson AutoDock is widely used and played a role in the development of the first cl ...
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Scripps Research
Scripps Research, previously known as The Scripps Research Institute (TSRI), is a nonprofit American medical research facility that focuses on research and education in the biomedical sciences. Headquartered in San Diego, California, the institute has over 170 laboratories employing 2,100 scientists, technicians, graduate students, and administrative and other staff, making it the largest private, non-profit biomedical research organization in the United States and among the largest in the world. The institute holds over 1,100 patents, has produced 11 FDA-approved therapeutics, and has generated over 50 spin-off companies. According to the 2017 Nature Innovation Index, Scripps Research is the #1 most influential research institution in the world. The Scripps Research graduate program is ranked 9th nationally in the biological sciences, 6th for organic chemistry, and 6th for biochemistry. In 2022, their Jupiter, FL campus became a part of the University of Florida. Jupiter-based ...
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Volunteer Computing Projects
Volunteering is a voluntary act of an individual or group freely giving time and labor for community service. Many volunteers are specifically trained in the areas they work, such as medicine, education, or emergency rescue. Others serve on an as-needed basis, such as in response to a natural disaster. Etymology and history The verb was first recorded in 1755. It was derived from the noun ''volunteer'', in 1600, "one who offers himself for military service," from the Middle French ''voluntaire''. In the non-military sense, the word was first recorded during the 1630s. The word ''volunteering'' has more recent usage—still predominantly military—coinciding with the phrase ''community service''. In a military context, a volunteer army is a military body whose soldiers chose to enter service, as opposed to having been conscripted. Such volunteers do not work "for free" and are given regular pay. 19th century During this time, America experienced the Great Awakening. P ...
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Berkeley Open Infrastructure For Network Computing Projects
Berkeley most often refers to: *Berkeley, California, a city in the United States **University of California, Berkeley, a public university in Berkeley, California *George Berkeley (1685–1753), Anglo-Irish philosopher Berkeley may also refer to: Places Australia * Berkeley, New South Wales, a suburb of Wollongong Canada * Berkeley, Ontario, a community in Grey County United Kingdom * Berkeley (hundred), an administrative division from late Saxon period to the 19th century * Berkeley, Gloucestershire, a town in England United States * Berkeley, California, a city in the San Francisco Bay Area, the largest city named Berkeley * Berkeley, Denver, a neighborhood in Denver, Colorado * Berkeley, Illinois, a suburb of Chicago * Berkeley, Missouri, a northwestern suburb of St. Louis * Berkeley Township, Ocean County, New Jersey * Berkeley, Rhode Island * Berkeley, Virginia (other) * Berkeley, West Virginia * Berkeley County (other) People * Berkeley (given nam ...
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Internet
The Internet (or internet) is the global system of interconnected computer networks that uses the Internet protocol suite (TCP/IP) to communicate between networks and devices. It is a '' network of networks'' that consists of private, public, academic, business, and government networks of local to global scope, linked by a broad array of electronic, wireless, and optical networking technologies. The Internet carries a vast range of information resources and services, such as the inter-linked hypertext documents and applications of the World Wide Web (WWW), electronic mail, telephony, and file sharing. The origins of the Internet date back to the development of packet switching and research commissioned by the United States Department of Defense in the 1960s to enable time-sharing of computers. The primary precursor network, the ARPANET, initially served as a backbone for interconnection of regional academic and military networks in the 1970s to enable resource shari ...
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Computer Graphics
Computer graphics deals with generating images with the aid of computers. Today, computer graphics is a core technology in digital photography, film, video games, cell phone and computer displays, and many specialized applications. A great deal of specialized hardware and software has been developed, with the displays of most devices being driven by computer graphics hardware. It is a vast and recently developed area of computer science. The phrase was coined in 1960 by computer graphics researchers Verne Hudson and William Fetter of Boeing. It is often abbreviated as CG, or typically in the context of film as computer generated imagery (CGI). The non-artistic aspects of computer graphics are the subject of computer science research. Some topics in computer graphics include user interface design, sprite graphics, rendering, ray tracing, geometry processing, computer animation, vector graphics, 3D modeling, shaders, GPU design, implicit surfaces, visualization, scientific c ...
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Hard Drive
A hard disk drive (HDD), hard disk, hard drive, or fixed disk is an electro-mechanical data storage device that stores and retrieves digital data using magnetic storage with one or more rigid rapidly rotating platters coated with magnetic material. The platters are paired with magnetic heads, usually arranged on a moving actuator arm, which read and write data to the platter surfaces. Data is accessed in a random-access manner, meaning that individual blocks of data can be stored and retrieved in any order. HDDs are a type of non-volatile storage, retaining stored data when powered off. Modern HDDs are typically in the form of a small rectangular box. Introduced by IBM in 1956, HDDs were the dominant secondary storage device for general-purpose computers beginning in the early 1960s. HDDs maintained this position into the modern era of servers and personal computers, though personal computing devices produced in large volume, like cell phones and tablets, rely on ...
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Megabyte
The megabyte is a multiple of the unit byte for digital information. Its recommended unit symbol is MB. The unit prefix ''mega'' is a multiplier of (106) in the International System of Units (SI). Therefore, one megabyte is one million bytes of information. This definition has been incorporated into the International System of Quantities. In the computer and information technology fields, other definitions have been used that arose for historical reasons of convenience. A common usage has been to designate one megabyte as (220 B), a quantity that conveniently expresses the binary architecture of digital computer memory. The standards bodies have deprecated this usage of the megabyte in favor of a new set of binary prefixes, in which this quantity is designated by the unit mebibyte (MiB). Definitions The unit megabyte is commonly used for 10002 (one million) bytes or 10242 bytes. The interpretation of using base 1024 originated as technical jargon for the byte SI prefix, mult ...
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Random Access Memory
Random-access memory (RAM; ) is a form of computer memory that can be read and changed in any order, typically used to store working Data (computing), data and machine code. A Random access, random-access memory device allows data items to be read (computer), read or written in almost the same amount of time irrespective of the physical location of data inside the memory, in contrast with other direct-access data storage media (such as hard disks, CD-RWs, DVD-RWs and the older Magnetic tape data storage, magnetic tapes and drum memory), where the time required to read and write data items varies significantly depending on their physical locations on the recording medium, due to mechanical limitations such as media rotation speeds and arm movement. RAM contains multiplexer, multiplexing and demultiplexing circuitry, to connect the data lines to the addressed storage for reading or writing the entry. Usually more than one bit of storage is accessed by the same address, and RAM ...
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