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Fiddler's Neck
Fiddler's neck is an occupational disease that affects violin and viola players. It is a cutaneous condition usually characterized by redness, thickening, and inflammation on the left side of the neck below the angle of the jaw where the instrument is held. Acne-like lesions and cysts may form at the site due to foreign body reactions, and infections may also occur due to poor hygiene. The primary causes of fiddler's neck are constant friction and local pressure. It is well known among professional orchestra musicians but is "not well recognized by dermatologists", and a red mark on the left side of the neck under the jaw "functions as an identifying sign" of a violinist or violist "in public without seeing the instrument"''.'' Although the presence of fiddler's neck is sometimes used as an indicator of a violinist's skill, or 'battle scars' from constant practice, many violinists never develop fiddler's neck, due to differences in skin sensitivity, playing habits, and the materia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Occupational Disease
An occupational disease is any chronic ailment that occurs as a result of work or occupational activity. It is an aspect of occupational safety and health. An occupational disease is typically identified when it is shown that it is more prevalent in a given body of workers than in the general population, or in other worker populations. The first such disease to be recognised, squamous-cell carcinoma of the scrotum, was identified in chimney sweep boys by Sir Percival Pott in 1775. Occupational hazards that are of a traumatic nature (such as falls by roofers) are not considered to be occupational diseases. Under the law of workers' compensation in many jurisdictions, there is a presumption that specific disease are caused by the worker being in the work environment and the burden is on the employer or insurer to show that the disease came about from another cause. Diseases compensated by national workers compensation authorities are often termed occupational diseases. However, m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dystrophic Calcinosis Cutis
Calcinosis cutis is a type of calcinosis wherein calcium deposits form in the skin. A variety of factors can result in this condition. The most common source is dystrophic calcification, which occurs in soft tissue as a response to injury. In addition, calcinosis is seen in Limited Cutaneous Systemic Sclerosis, also known as CREST syndrome (the "C" in CREST). In dogs, calcinosis cutis is found in young, large breed dogs and is thought to occur after a traumatic injury. Causes Calcinosis may result from a variety of causes such as: *Trauma to the region *Inflammation (bug bites, acne) *Varicose veins *Infections *Tumors (malignant or benign) *Diseases of connective tissue *Hypercalcemia *Hyperphosphatemia Calcinosis cutis is associated with systemic sclerosis. Diagnosis Types Calcinosis cutis may be divided into the following types: * Dystrophic calcinosis cutis * Metastatic calcinosis cutis * Iatrogenic calcinosis cutis * Traumatic calcinosis cutis * Idiopathic calcino ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ebony
Ebony is a dense black/brown hardwood, coming from several species in the genus ''Diospyros'', which also contains the persimmons. Unlike most woods, ebony is dense enough to sink in water. It is finely textured and has a mirror finish when polished, making it valuable as an ornamental wood. The word ''ebony'' comes from the Ancient Egyptian ', through the Ancient Greek ('), into Latin and Middle English. Species Species of ebony include ''Diospyros ebenum'' (Ceylon ebony), native to southern India and Sri Lanka; '' D. crassiflora'' (Gabon ebony), native to western Africa; and '' D. celebica'' (Sulawesi ebony), native to Indonesia and prized for its luxuriant, multi-colored wood grain. Mauritius ebony, '' D. tessellaria'', was largely exploited by the Dutch in the 17th century. Some species in the genus yield an ebony with similar physical properties, but striped rather than the even black of ''D. ebenum''. Uses Ebony has a long history of use, and carved pieces have be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rosewood
Rosewood refers to any of a number of richly hued timbers, often brownish with darker veining, but found in many different hues. True rosewoods All genuine rosewoods belong to the genus ''Dalbergia''. The pre-eminent rosewood appreciated in the Western world is the wood of ''Dalbergia nigra''. It is best known as "Brazilian rosewood", but also as "Bahia rosewood". This wood has a strong, sweet smell, which persists for many years, explaining the name ''rosewood''. Another classic rosewood comes from ''Dalbergia latifolia'', known as (East) Indian rosewood or ''sonokeling'' (Indonesia). It is native to India and is also grown in plantations elsewhere in Pakistan (Chiniot). Madagascar rosewood (''Dalbergia maritima''), known as ''bois de rose'', is highly prized for its red color. It is overexploited in the wild, despite a 2010 moratorium on trade and illegal logging, which continues on a large scale. Throughout southeast Asia, ''Dalbergia oliveri'' is harvested for use in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Type I Hypersensitivity
Type I hypersensitivity (or immediate hypersensitivity), in the Gell and Coombs classification of allergic reactions, is an allergic reaction provoked by re-exposure to a specific type of antigen referred to as an allergen. Type I is distinct from type II, type III and type IV hypersensitivities. The relevance of the Gell and Coombs classification of allergic reactions has been questioned in the modern-day understanding of allergy, and it has limited utility in clinical practice. Exposure may be by ingestion, inhalation, injection, or direct contact. Pathophysiology In type I hypersensitivity, B cells are stimulated (by CD4+ Th2 cells) to produce IgE antibodies specific to an antigen. The difference between a normal infectious immune response and a type 1 hypersensitivity response is that in type 1 hypersensitivity, the antibody is IgE instead of IgA, IgG, or IgM. During sensitization, the IgE antibodies bind to FcεRI receptors on the surface of tissue mast ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sarcoidosis
Sarcoidosis (also known as ''Besnier-Boeck-Schaumann disease'') is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomata. The disease usually begins in the lungs, skin, or lymph nodes. Less commonly affected are the eyes, liver, heart, and brain. Any organ can be affected though. The signs and symptoms depend on the organ involved. Often, no, or only mild, symptoms are seen. When it affects the lungs, wheezing, coughing, shortness of breath, or chest pain may occur. Some may have Löfgren syndrome with fever, large lymph nodes, arthritis, and a rash known as erythema nodosum. The cause of sarcoidosis is unknown. Some believe it may be due to an immune reaction to a trigger such as an infection or chemicals in those who are genetically predisposed. Those with affected family members are at greater risk. Diagnosis is partly based on signs and symptoms, which may be supported by biopsy. Findings that make it likely include large lymph n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rosacea
Rosacea is a long-term skin condition that typically affects the face. It results in redness, pimples, swelling, and small and superficial dilated blood vessels. Often, the nose, cheeks, forehead, and chin are most involved. A red, enlarged nose may occur in severe disease, a condition known as rhinophyma. The cause of rosacea is unknown. Risk factors are believed to include a family history of the condition. Factors that may potentially worsen the condition include heat, exercise, sunlight, cold, spicy food, alcohol, menopause, psychological stress, or steroid cream on the face. Diagnosis is based on symptoms. While not curable, treatment usually improves symptoms. Treatment is typically with metronidazole, doxycycline, minocycline, or tetracycline. When the eyes are affected, azithromycin eye drops may help. Other treatments with tentative benefit include brimonidine cream, ivermectin cream, and isotretinoin. Dermabrasion or laser surgery may also be used. The use ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Granulomas
A granuloma is an aggregation of macrophages that forms in response to chronic inflammation. This occurs when the immune system attempts to isolate foreign substances that it is otherwise unable to eliminate. Such substances include infectious organisms including bacteria and fungi, as well as other materials such as foreign objects, keratin, and suture fragments. Definition In pathology, a granuloma is an organized collection of macrophages. In medical practice, doctors occasionally use the term ''granuloma'' in its more literal meaning: "a small nodule". Since a small nodule can represent any tissue from a harmless nevus to a malignant tumor, this use of the term is not very specific. Examples of this use of the term ''granuloma'' are the lesions known as vocal cord granuloma (known as contact granuloma), pyogenic granuloma, and intubation granuloma, all of which are examples of granulation tissue, not granulomas. "Pulmonary hyalinizing granuloma" is a lesion characterized ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acanthosis
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. The epidermis layer provides a barrier to infection from environmental pathogens and regulates the amount of water released from the body into the atmosphere through transepidermal water loss. The epidermis is composed of multiple layers of flattened cells that overlie a base layer (stratum basale) composed of columnar cells arranged perpendicularly. The layers of cells develop from stem cells in the basal layer. The human epidermis is a familiar example of epithelium, particularly a stratified squamous epithelium. The word epidermis is derived through Latin , itself and . Something related to or part of the epidermis is termed epidermal. Structure Cellular components The epidermis primarily consists of keratinocytes ( proliferating basal and differentiated suprabasal), which comprise 90% of its cells, but also contains melanocytes, Langerhans ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyperkeratosis
Hyperkeratosis is thickening of the stratum corneum (the outermost layer of the epidermis, or skin), often associated with the presence of an abnormal quantity of keratin,Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) ''Robbins & Cotran Pathologic Basis of Disease'' (7th ed.). Saunders. Page 1230. . and also usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed to assess minor degrees of hyperkeratosis. It can be caused by vitamin A deficiency or chronic exposure to arsenic. Hyperkeratosis can also be caused by B-Raf inhibitor drugs such as Vemurafenib and Dabrafenib.Niezgoda, Anna; Niezgoda, Piotr; Czajkowski, Rafal (2015) ''Novel Approaches to Treatment of Advanced Melanoma: A Review of Targeted Therapy and Immunotherapy'' BioMed Research International It can be treated with urea-containing creams, which dissolve the intercellular matrix of the cells of the stratum co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histopathology
Histopathology (compound of three Greek words: ''histos'' "tissue", πάθος ''pathos'' "suffering", and -λογία '' -logia'' "study of") refers to the microscopic examination of tissue in order to study the manifestations of disease. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides. In contrast, cytopathology examines free cells or tissue micro-fragments (as "cell blocks"). Collection of tissues Histopathological examination of tissues starts with surgery, biopsy, or autopsy. The tissue is removed from the body or plant, and then, often following expert dissection in the fresh state, placed in a fixative which stabilizes the tissues to prevent decay. The most common fixative is 10% neutral buffered formalin (corresponding to 3.7% w/v formaldehyde in neutral buffered water, such as phosphate buf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parotid Gland
The parotid gland is a major salivary gland in many animals. In humans, the two parotid glands are present on either side of the mouth and in front of both ears. They are the largest of the salivary glands. Each parotid is wrapped around the mandibular ramus, and secretes serous saliva through the parotid duct into the mouth, to facilitate mastication and swallowing and to begin the digestion of starches. There are also two other types of salivary glands; they are submandibular and sublingual glands. Sometimes accessory parotid glands are found close to the main parotid glands. Etymology The word ''parotid'' literally means "beside the ear". From Greek παρωτίς (stem παρωτιδ-) : (gland) behind the ear < παρά - pará : in front, and οὖς - ous (stem ὠτ-, ōt-) : ear. Structure The parotid glands are a pair of mainly |
