Faggot Cell
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Faggot Cell
Faggot cells are cells normally found in the hypergranular form of acute promyelocytic leukemia (FAB - M3). These promyelocytes (not blast cells) have numerous Auer rods in the cytoplasm which gives the appearance of a bundle of sticks, from which the cells are given their name. See also * Buttock cell Buttock cells are cells having a notched appearance that are found in certain malignancies, such as non-Hodgkin's lymphoma (including follicular lymphoma), mycosis fungoides, and Sézary syndrome. See also * Clue cell * Koilocyte * Large cell ... References {{Reflist Human cells Pathology Hematology Acute myeloid leukemia ...
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Faggot Cell In AML-M3
Faggot, faggots, or faggoting may refer to: Arts and crafts * Faggoting (metalworking), forge welding a bundle of bars of iron and steel * Faggoting (knitting), variation of lace knitting in which every stitch is a yarn over or a decrease * Faggoting stitch, featherstitch, or Cretan stitch, embroidery stitch used to make decorative seams or to attach insertions * Bassoon, called fagotto, faggot, fagott, fagot in other languages Biology * Faggot cell, cell type found in acute promyelocytic leukemia * '' Eumeta crameri'' or faggot worm, from the bundles of twigs it binds to itself Branch * faggot or fagot, branch or twig, or bundle of these ** Fascine, bundle of brushwood used in civil and military engineering ** Fasces, ancient symbol of an axe bound in a bundle of rods ** Faggot (unit), archaic unit of measurement for bundles of sticks Food * Faggot (food), British meatball commonly made of pork offal Slang * Faggot (slang), a pejorative for a gay man :* ''Faggot ...
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Acute Promyelocytic Leukemia
Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARA) gene and is distinguished from other forms of AML by its responsiveness to all-''trans'' retinoic acid (ATRA; also known as tretinoin) therapy. Acute promyelocytic leukemia was first characterized in 1957 by French and Norwegian physicians as a hyperacute fatal illness, with a median survival time of less than a week. Today, prognoses have drastically improved; 10-year survival rates are estimated to be approximately 80-90% according to one study. Signs and symptoms The symptoms tend to be similar to AML in general with the following being possible symptoms: * Anemia * Fatigue * Weakness * Chills * Depression * Difficulty breathing (dyspnea) * Low platelets (thr ...
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Auer Rods
Auer rods (or Auer bodies) are large, crystalline cytoplasmic inclusion bodies sometimes observed in myeloid blast cells during acute myeloid leukemia, acute promyelocytic leukemia, high-grade myelodysplastic syndromes and myeloproliferative disorders. Composed of fused lysosomes and rich in lysosomal enzymes, Auer rods are azurophilic and can resemble needles, commas, diamonds, rectangles, corkscrews, or (rarely) granules. Eponym Although Auer rods are named for American physiologist John Auer, they were first described in 1905 by Canadian physician Thomas McCrae, then at Johns Hopkins Hospital, as Auer himself acknowledged in his 1906 paper. Both McCrae and Auer mistakenly thought that the cells containing the rods were lymphoblasts. Additional images Image:Myeloblast with Auer rod smear 2010-01-27.JPG, Bone marrow aspirate showing acute myeloid leukemia with Auer rods in several blasts Image:Myeloblast whith Auer rod 2009-09-21.JPG Image:Myeloblast with Auer Rod smear 2009 ...
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Cytoplasm
In cell biology, the cytoplasm is all of the material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus. The material inside the nucleus and contained within the nuclear membrane is termed the nucleoplasm. The main components of the cytoplasm are cytosol (a gel-like substance), the organelles (the cell's internal sub-structures), and various cytoplasmic inclusions. The cytoplasm is about 80% water and is usually colorless. The submicroscopic ground cell substance or cytoplasmic matrix which remains after exclusion of the cell organelles and particles is groundplasm. It is the hyaloplasm of light microscopy, a highly complex, polyphasic system in which all resolvable cytoplasmic elements are suspended, including the larger organelles such as the ribosomes, mitochondria, the plant plastids, lipid droplets, and vacuoles. Most cellular activities take place within the cytoplasm, such as many metabolic pathways including glycolysis, and proces ...
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Faggot (unit)
A faggot, in the meaning of "bundle", is an archaic English unit applied to bundles of certain items. Alternate spellings in Early Modern English include ''fagate, faget, fagett, faggott, fagot, fagatt, fagott, ffagott,'' and ''faggat''. A similar term is found in other languages (e.g. Latin: ''fascis''). Background Sometimes called a short faggot, a faggot of sticks equals a bundle of wood sticks or billets that is in length and in circumference. The measurement was standardised in ordinances by 1474. A small short faggot was also called a nicket. A brush-faggot (sometimes shortened to brush) was a bundle of similar size made of brushwood. A long faggot of sticks equals a bundle larger than long. In a book on slang used at Winchester College fire-dogs were fire basket (andirons) that could hold long faggots, and half-faggots were smaller andirons that could only hold short faggots and were later converted for use with coal. A long faggot was also called a kidd faggot,Yaxley, ...
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Buttock Cell
Buttock cells are cells having a notched appearance that are found in certain malignancies, such as non-Hodgkin's lymphoma (including follicular lymphoma), mycosis fungoides, and Sézary syndrome. See also * Clue cell * Koilocyte * Large cell Large cell is a term used in oncology. It does not refer to a particular type of cell; rather it refers to cells that are larger than would be normally expected for that type. It is frequently used when describing lymphoma and lung cancer. It was ... References Blood cells Lymphoma {{oncology-stub ...
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Human Cells
There are many different types of cells in the human body. Cells derived primarily from endoderm Exocrine secretory epithelial cells * Brunner's gland cell in duodenum (enzymes and alkaline mucus) *Insulated goblet cell of respiratory and digestive tracts (mucus secretion) *Stomach **Foveolar cell (mucus secretion) **Chief cell ( pepsinogen secretion) **Parietal cell (hydrochloric acid secretion) * Pancreatic acinar cell (bicarbonate and digestive enzyme secretion) *Paneth cell of small intestine (lysozyme secretion) *Type II pneumocyte of lung (surfactant secretion) *Club cell of lung Barrier cells *Type I pneumocyte (lung) * Gall bladder epithelial cell * Centroacinar cell (pancreas) *Intercalated duct cell (pancreas) *Intestinal brush border cell (with microvilli) Hormone-secreting cells *Enteroendocrine cell **K cell (secretes gastric inhibitory peptide) **L cell (secretes glucagon-like peptide-1, peptide YY3-36, oxyntomodulin, and glucagon-like peptide-2) **I cel ...
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Pathology
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomy ...
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Hematology
Hematology ( always spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the production of blood and its components, such as blood cells, hemoglobin, blood proteins, bone marrow, platelets, blood vessels, spleen, and the mechanism of coagulation. Such diseases might include hemophilia, blood clots (thrombus), other bleeding disorders, and blood cancers such as leukemia, multiple myeloma, and lymphoma. The laboratory analysis of blood is frequently performed by a medical technologist or medical laboratory scientist. Specialization Physicians specialized in hematology are known as hematologists or haematologists. Their routine work mainly includes the care and treatment of patients with hematological diseases, although some may also work at the hematology laboratory viewing blood films and bone marrow slides under the ...
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