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FDC-SP
FDC-SP or follicular dendritic cell-secreted protein, is a small, secreted protein, located on chromosome 4 in humans. It is thought to play an immune role in the junctional epithelium at the gingiva, gingival crevice in the human mouth. It is very similar in structure to statherin, a protein contained in saliva. Structure and genetics FDC-SP is a 68-amino acid protein containing a signal peptide at its N terminus, which is used for directing the transport of the protein. Adjacent to the signal peptide, the protein contains a highly charged N-terminal sequence. The C-terminal half of FDC-SP is proline-rich and not highly Conserved sequence, conserved between species, but the alignment of proline residues within this region is highly conserved. FDC-SP homologues are only easily located within the human, rat, mouse and Common chimpanzee, chimpanzee genome. There is a 70% sequence homology between mouse and rat and a 45% homology between human and mouse. The N-terminal, however, is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FDC-SP Image 2
FDC-SP or follicular dendritic cell-secreted protein, is a small, secreted protein, located on chromosome 4 in humans. It is thought to play an immune role in the junctional epithelium at the gingiva, gingival crevice in the human mouth. It is very similar in structure to statherin, a protein contained in saliva. Structure and genetics FDC-SP is a 68-amino acid protein containing a signal peptide at its N terminus, which is used for directing the transport of the protein. Adjacent to the signal peptide, the protein contains a highly charged N-terminal sequence. The C-terminal half of FDC-SP is proline-rich and not highly Conserved sequence, conserved between species, but the alignment of proline residues within this region is highly conserved. FDC-SP homologues are only easily located within the human, rat, mouse and Common chimpanzee, chimpanzee genome. There is a 70% sequence homology between mouse and rat and a 45% homology between human and mouse. The N-terminal, however, is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
