Eubacterium Oxidoreducens
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Eubacterium Oxidoreducens
''Eubacterium oxidoreducens'' is a Gram positive bacterium species in the genus ''Eubacterium''. 1,2,3,5-Tetrahydroxybenzene is a benzenetetrol and a metabolite in the degradation of 3,4,5-trihydroxybenzoate by ''E. oxidoreducens''.Initial steps in the anaerobic degradation of 3,4,5-trihydroxybenzoate by Eubacterium oxidoreducens: characterization of mutants and role of 1,2,3,5-tetrahydroxybenzene. J D Haddock and J G Ferry, J Bacteriol., February 1993, volume 175, issue 3, pages 669-673abstract The enzyme phloroglucinol reductase uses dihydrophloroglucinol and NADP+ to produce phloroglucinol Phloroglucinol is an organic compound with the formula C6H3(OH)3. It is a colorless solid. It is used in the synthesis of pharmaceuticals and explosives. Phloroglucinol is one of three isomeric benzenetriols. The other two isomers are hydroxyqu ..., NADPH, and H+. It is found in ''E. oxidoreducens''. References External links Type strain of ''Eubacterium oxidoreducens'' at Bac ...
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Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic relationsh ...
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Bacillota
The Bacillota (synonym Firmicutes) are a phylum of bacteria, most of which have gram-positive cell wall structure. The renaming of phyla such as Firmicutes in 2021 remains controversial among microbiologists, many of whom continue to use the earlier names of long standing in the literature. The name "Firmicutes" was derived from the Latin words for "tough skin," referring to the thick cell wall typical of bacteria in this phylum. Scientists once classified the Firmicutes to include all gram-positive bacteria, but have recently defined them to be of a core group of related forms called the low- G+C group, in contrast to the Actinomycetota. They have round cells, called cocci (singular coccus), or rod-like forms (bacillus). A few Firmicutes, such as ''Megasphaera'', ''Pectinatus'', ''Selenomonas'' and ''Zymophilus'', have a porous pseudo-outer membrane that causes them to stain gram-negative. Many Bacillota (Firmicutes) produce endospores, which are resistant to desiccation and can ...
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Clostridia
The Clostridia are a highly polyphyletic class of Bacillota, including '' Clostridium'' and other similar genera. They are distinguished from the Bacilli by lacking aerobic respiration. They are obligate anaerobes and oxygen is toxic to them. Species of the class ''Clostridia'' are often but not always Gram-positive (see ''Halanaerobium'') and have the ability to form spores. Studies show they are not a monophyletic group, and their relationships are not entirely certain. Currently, most are placed in a single order called Clostridiales, but this is not a natural group and is likely to be redefined in the future. Most species of the genus ''Clostridium'' are saprophytic organisms that ferment plant polysaccharides and are found in many places in the environment, most notably the soil. However, the genus does contain some human pathogens (outlined below). The toxins produced by certain members of the genus ''Clostridium'' are among the most dangerous known. Examples are tetanus ...
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Eubacteriaceae
The Eubacteriaceae are a family of Gram-positive bacteria in the order Clostridiales. Phylogeny The currently accepted taxonomy based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and the National Center for Biotechnology Information (NCBI). See also * List of bacterial orders * List of bacteria genera This article lists the genera of the bacteria. The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI). However many taxonomic names are ... References External links {{Clostridia-stub ...
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Eubacterium
''Eubacterium'' is a genus of Gram-positive bacteria in the family Eubacteriaceae. These bacteria are characterised by a rigid cell wall. They may either be motile or nonmotile. If motile, they have a flagellum A flagellum (; ) is a hairlike appendage that protrudes from certain plant and animal sperm cells, and from a wide range of microorganisms to provide motility. Many protists with flagella are termed as flagellates. A microorganism may have f .... A typical flagellum consists of a basal body, filament, and hook. The long filament is the organ which helps eubacteria move. Gram-positive bacteria have a thick proteoglycan layer and take up violet Gram stain (whereas Gram-negative bacteria have a thinner proteoglycan layer which is surrounded by a layer of immune response-inducing lipopolysaccharide, and do not take up Gram stain). References Eubacteriaceae Bacterial vaginosis Bacteria genera {{Clostridia-stub ...
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LPSN
List of Prokaryotic names with Standing in Nomenclature (LPSN) is an online database that maintains information on the naming and taxonomy of prokaryotes, following the taxonomy requirements and rulings of the International Code of Nomenclature of Prokaryotes The International Code of Nomenclature of Prokaryotes (ICNP) formerly the International Code of Nomenclature of Bacteria (ICNB) or Bacteriological Code (BC) governs the scientific names for Bacteria and Archaea.P. H. A. Sneath, 2003. A short hist .... The database was curated from 1997 to June 2013 by Jean P. Euzéby. From July 2013 to January 2020, LPSN was curated by Aidan C. Parte. In February 2020, a new version of LPSN was published as a service of the Leibniz Institute DSMZ, thereby also integrating the Prokaryotic Nomenclature Up-to-date service. References External links List of Prokaryotic names with Standing in Nomenclature
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1,2,3,5-Tetrahydroxybenzene
1,2,3,5-Tetrahydroxybenzene is a benzenetetrol. It is a metabolite in the degradation of 3,4,5-trihydroxybenzoate (gallic acid) by ''Eubacterium oxidoreducens''. The enzyme pyrogallol hydroxytransferase uses 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene (pyrogallol), whereas its two products are 1,3,5-trihydroxybenzene (phloroglucinol) and 1,2,3,5-tetrahydroxybenzene.Pyrogallol hydroxytransferase
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See also

* Trihydroxybenzenes *
Pentahydroxybenzene Pentahydroxybenzene (C6H6O5) is a chemical compound whose structure consists of a benzene ...
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3,4,5-trihydroxybenzoate
Gallic acid (also known as 3,4,5-trihydroxybenzoic acid) is a trihydroxybenzoic acid with the formula C6 H2( OH)3CO2H. It is classified as a phenolic acid. It is found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and other plants. It is a white solid, although samples are typically brown owing to partial oxidation. Salts and esters of gallic acid are termed "gallates". Isolation and derivatives Gallic acid is easily freed from gallotannins by acidic or alkaline hydrolysis. When heated with concentrated sulfuric acid, gallic acid converts to rufigallol. Hydrolyzable tannins break down on hydrolysis to give gallic acid and glucose or ellagic acid and glucose, known as gallotannins and ellagitannins, respectively. Biosynthesis Gallic acid is formed from 3-dehydroshikimate by the action of the enzyme shikimate dehydrogenase to produce 3,5-didehydroshikimate. This latter compound aromatizes. Reactions Oxidation and oxidative coupling Alkaline solutions of gallic a ...
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Phloroglucinol Reductase
In enzymology, a phloroglucinol reductase () is an enzyme that catalysis, catalyzes the chemical reaction :dihydrophloroglucinol + NADP+ \rightleftharpoons phloroglucinol + NADPH + H+ Thus, the two substrate (biochemistry), substrates of this enzyme are dihydrophloroglucinol and nicotinamide adenine dinucleotide phosphate, NADP+, whereas its 3 product (chemistry), products are phloroglucinol, nicotinamide adenine dinucleotide phosphate, NADPH, and hydrogen ion, H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The List of enzymes, systematic name of this enzyme class is dihydrophloroglucinol:NADP+ oxidoreductase. This enzyme participates in benzoate degradation via coa ligation. References

* EC 1.3.1 NADPH-dependent enzymes Enzymes of unknown structure {{1.3-enzyme-stub ...
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Dihydrophloroglucinol
Dihydrophloroglucinol is a chemical compound found in the pathway of the microbial degradation of phloroglucinol and other phenolic compounds. The enzyme phloroglucinol reductase uses dihydrophloroglucinol and NADP+ to produce phloroglucinol, NADPH Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NAD ..., and H+. It is found in the bacterium species '' Eubacterium oxidoreducens''. References Cyclohexenols 3-Hydroxypropenals {{ketone-stub ...
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Phloroglucinol
Phloroglucinol is an organic compound with the formula C6H3(OH)3. It is a colorless solid. It is used in the synthesis of pharmaceuticals and explosives. Phloroglucinol is one of three isomeric benzenetriols. The other two isomers are hydroxyquinol (1,2,4-benzenetriol) and pyrogallol (1,2,3-benzenetriol). Phloroglucinol, and its benzenetriol isomers, are still defined as "phenols" according to the IUPAC official nomenclature rules of chemical compounds. Many such monophenolics are often termed "polyphenols" by the cosmetic and parapharmaceutical industries, which does not match the scientifically accepted definition. Synthesis and occurrence In 1855, phloroglucinol was first prepared from phloretin by the Austrian chemist Heinrich Hlasiwetz (1825–1875). A modern synthesis of involves hydrolysis of benzene-1,3,5-triamine and its derivatives. Representative is the following route from trinitrobenzene. : The synthesis is noteworthy because ordinary aniline derivatives are unre ...
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