Ernst Bamberg
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Ernst Bamberg
Ernst Bamberg (b. in Krefeld) is a German biophysicist and director emeritus of the Department of Biophysical Chemistry at the Max Planck Institute of Biophysics. Career Bamberg received his PhD in physical chemistry from the University of Basel in 1971, and a habilitation in biophysical chemistry from the University of Konstanz in 1976. He was a Heisenberg fellow from 1979 to 1983, when he became head of an independent working group at the Max Planck Institute of Biophysics in Frankfurt/Main. In 1988, he became an adjunct professor at Frankfurt University, which named him a full professor of biophysical chemistry in 1993, and professor emeritus in 2009. He has also been a director and Scientific Member at the Max Planck Institute of Biophysics since 1993, and a senior investigator at the Cluster of Excellence Frankfurt (CEF) since 2008. Research Bamberg's research focuses on channelrhodopsins. With Georg Nagel and Peter Hegemann, who were attempting to identify the protei ...
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Krefeld
Krefeld ( , ; li, Krieëvel ), also spelled Crefeld until 1925 (though the spelling was still being used in British papers throughout the Second World War), is a city in North Rhine-Westphalia, Germany. It is located northwest of Düsseldorf, its center lying just a few kilometers to the west of the river Rhine; the borough of Uerdingen is situated directly on the Rhine. Because of its economic past, Krefeld is often referred to as the "Velvet and Silk City". It is accessed by the autobahns A57 (Cologne– Nijmegen) and A44 (Aachen–Düsseldorf– Dortmund–Kassel). Krefeld's residents now speak ', or standard German, but the native dialect is a Low Franconian variety, sometimes locally called ', ', ', or sometimes simply '. The Uerdingen line isogloss, separating general dialectical areas in Germany and neighboring Germanic-speaking countries, runs through and is named after Krefeld's Uerdingen district, originally an independent municipality. History Early history Records ...
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Photocurrent
Photocurrent is the electric current through a photosensitive device, such as a photodiode, as the result of exposure to radiant power. The photocurrent may occur as a result of the photoelectric, photoemissive, or photovoltaic effect. The photocurrent may be enhanced by internal gain caused by interaction among ions and photons under the influence of applied fields, such as occurs in an avalanche photodiode (APD). When a suitable radiation is used, the photoelectric current is directly proportional to intensity of radiation and increases with the increase in accelerating potential till the stage is reached when photo-current becomes maximum and does not increase with further increase in accelerating potential. The highest (maximum) value of the photo-current is called saturation current. The value of retarding potential at which photo-current becomes zero is called cut-off voltage or stopping potential for the given frequency of the incident ray. Photovoltaics The generation ...
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Rumford Prize
Founded in 1796, the Rumford Prize, awarded by the American Academy of Arts and Sciences, is one of the oldest scientific prizes in the United States. The prize recognizes contributions by scientists to the fields of heat and light. These terms are widely interpreted; awards range from discoveries in thermodynamics to improvements in the construction of steam boilers. The award was created through the endowment of US$5,000 to the Academy by Benjamin Thompson, who held the title "Count Rumford of the United Kingdom," in 1796. The terms state that the award be given to "authors of discoverie's in any part of the Continent of America, or in any of the American islands." Although it was founded in 1796, the first prize was not given until 1839, as the academy could not find anyone who, in their judgement, deserved the award. The academy found the terms of the prize to be too restrictive, and in 1832 the Supreme Court of Massachusetts allowed the Academy to change some of the provisi ...
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Gero Miesenböck
Gero Andreas Miesenböck (born 15 July 1965) is an Austrian scientist. He is currently Waynflete Professor of Physiology and Director of the Centre for Neural Circuits and Behaviour (CNCB) at the University of Oxford and a fellow of Magdalen College, Oxford. Education and early life A native of Austria, Miesenböck was educated at the University of Innsbruck and Umeå University in Sweden. He graduated sub auspiciis praesidentis rei publicae from the University of Innsbruck Medical School. Following his Doctor of Medicine (MD) in 1993, he undertook postdoctoral training with James Rothman. Research and career Miesenböck is known as the founder of optogenetics. He was the first scientist to modify nerve cells genetically so that their electrical activity could be controlled with light. This involved inserting DNA for light-responsive opsin proteins into the cells. Miesenböck used similar genetic modifications to breed animals whose brains contained light-responsive ne ...
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The Brain Prize
The Brain Prize, formerly known as The Grete Lundbeck European Brain Research Prize, is an international scientific award honouring "one or more scientists who have distinguished themselves by an outstanding contribution to neuroscience and who are still active in research". Founded in 2011 by thLundbeck Foundation the prize is associated with a DKK 10 million award to the nominees, the world’s largest brain research prize. Nominees can be of any nationality. Prize winners are expected to interact with Danish brain researchers e.g. through lectures, master classes, seminars, exchange programmes for researchers or other activities agreed with and financially supported by the Lundbeck Foundation. History The Brain Prize was established by the Lundbeck Foundation in 2010 as a European prize and was awarded for the first time in 2011. Today the Prize is global. Selection committee As of 2019, the selection committee for the prize consisted of: * Richard G. Morris (chair) * Story Lan ...
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Academy Of Sciences Leopoldina
The German National Academy of Sciences Leopoldina (german: Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften), short Leopoldina, is the national academy of Germany, and is located in Halle (Saale). Founded on January 1, 1652, based on academic models in Italy, it was originally named the ''Academia Naturae Curiosorum'' until 1687 when Emperor Leopold I raised it to an academy and named it after himself. It was since known under the German name ''Deutsche Akademie der Naturforscher Leopoldina'' until 2007, when it was declared to be Germany's National Academy of Sciences. History ' The Leopoldina was founded in the imperial city of Schweinfurt on 1 January 1652 under the Latin name sometimes translated into English as "Academy of the Curious as to Nature." It was founded by four local physicians- Johann Laurentius Bausch, the first president of the society, Johann Michael Fehr, Georg Balthasar Metzger, and Georg Balthasar Wohlfarth; and ...
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Wiley Prize In Biomedical Sciences
The Wiley Prize in Biomedical Sciences is intended to recognize breakthrough research in pure or applied life science research that is distinguished by its excellence, originality and impact on our understanding of biological systems and processes. The award may recognize a specific contribution or series of contributions that demonstrate the nominee’s significant leadership in the development of research concepts or their clinical application. Particular emphasis will be placed on research that champions novel approaches and challenges accepted thinking in the biomedical sciences. The Wiley Foundation, established in 2001, is the endowing body that supports the Wiley Prize in Biomedical Sciences. This international award is presented annually and consists of a $35,000 prize and a luncheon in honor of the recipient. The award is presented at a ceremony at The Rockefeller University, where the recipient delivers an honorary lecture as part of the Rockefeller University Lecture Se ...
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Boris Rajewsky
Boris Rajewsky (russian: Борис Николаевич Раевский; ukr, Борис Миколайович Раєвський; 17 July 1893 – 22 November 1974) was a Russian Empire, Russian-born Germany, German biophysicist, who was one of the most influential researchers on the impact of radiation on living organisms in the 20th century. He served as Rector of the Goethe University Frankfurt from 1949 to 1951. Life and career He was the son of a Ukrainian people, Ukrainian noble family and grew up in the Russian Empire. He studied physics at the University of Kyiv, St. Vladimir Imperial University of Kiev from 1912, and obtained a doctorate there in 1918. He moved to Germany in 1922 and became a German citizen in 1927. He became the assistant of Friedrich Dessauer and obtained an additional doctorate at the Goethe University in 1929. In 1934 he became Professor of Physics at the Goethe University, and in 1943 he became Pro-Rector of the university. He served as the unive ...
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Optogenetics
Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells. On the level of individual cells, light-activated enzymes and transcription factors allow precise control of biochemical signaling pathways. In systems neuroscience, the ability to control the activity of a genetically defined set of neurons has been used to understand their contribution to decision making, learning, fear memory, mating, addiction, feeding, and locomotion. In a first medical application of optogenetic technology, vision was partially restored in a blind patient. Optogenetic techniques have also been introduced to map the functional connectivity of the brain''.'' By altering the activity of genetically labelled neurons with light and using imaging and electrophysiology techniques to record the activity of other cells, researchers can identify ...
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Light-gated Ion Channel
Light-gated ion channels are a family of ion channels regulated by electromagnetic radiation. Other gating mechanisms for ion channels include voltage-gated ion channels, ligand-gated ion channels, mechanosensitive ion channels, and temperature-gated ion channels. Most light-gated ion channels have been synthesized in the laboratory for study, although two naturally occurring examples, channelrhodopsin and anion-conducting channelrhodopsin, are currently known. Photoreceptor proteins, which act in a similar manner to light-gated ion channels, are generally classified instead as G protein-coupled receptors. Mechanism Light-gated ion channels function in a similar manner to other gated ion channels. Such transmembrane proteins form pores through lipid bilayers to facilitate the passage of ions. These ions move from one side of the membrane to another under the influence of an electrochemical gradient. When exposed to a stimulus, a conformational change occurs in the transmembrane ...
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Feng Zhang
Feng Zhang (; born October 22, 1981) is a Chinese-American biochemist. Zhang currently holds the James and Patricia Poitras Professorship in Neuroscience at the McGovern Institute for Brain Research and in the departments of Brain and Cognitive Sciences and Biological Engineering at the Massachusetts Institute of Technology. He also has appointments with the Broad Institute of MIT and Harvard (where he is a core member). He is most well known for his central role in the development of optogenetics and CRISPR technologies. Early life and education Zhang was born in China in 1981 and given the name 锋 (which means "point of a spear; edge of a tool; vanguard"). Both of his parents were computer programmers in China. At age 11, he moved to Iowa with his mother (his father was not able to join them for several years). He attended Theodore Roosevelt High School and Central Academy in Des Moines, graduating in 2000. In 1999 he attended the acclaimed Research Science Institute at M ...
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