Elizabeth Lee Hazen
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Elizabeth Lee Hazen
Elizabeth Lee Hazen (August 24, 1885 in Mississippi – June 24, 1975) is most known for her contribution to the development of nystatin. Her education focused on science and research where she developed a passion for microbiology. Her peers and teachers knew her as a quick learner and a bright student. In 1948, she teamed up with Rachel Fuller Brown to develop nystatin, the first non-toxic drug treatment for fungal infections in humans. Her research had multiple applications ranging from saving infected trees to restoring paintings and artwork damaged due to mold. Early life Elizabeth Lee Hazen was born on August 24, 1885, in Rich, Mississippi, to William Edgar Hazen and Maggie Harper Hazen. She was their second daughter and middle of three children.Laura Lynn Windsor, ''Women in Medicine: An Encyclopedia'', '' ABC-CLIO'', 2002, pp. 92–93. Her parents died when she was four, and the three children were adopted by an aunt and uncle.Benjamin F. Shearer, Barbara Smith Shearer, ' ...
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Rachel Fuller Brown
Rachel Fuller Brown (November 23, 1898 – January 14, 1980) was a chemist best known for her long-distance collaboration with microbiologist Elizabeth Lee Hazen in developing the first useful antifungal antibiotic, nystatin, while doing research for the Division of Laboratories and Research of the New York State Department of Health. Brown received her B.A. from Mount Holyoke College and her Ph.D from the University of Chicago. She was inducted into the National Inventors Hall of Fame in 1994. Nystatin, still produced today under various trade names, not only cures a variety of potentially devastating fungal infections, but has also been used to combat Dutch Elm disease in trees and to restore artwork damaged by water and mold. Life On November 23, 1898, Rachel Fuller Brown was born in Springfield, Massachusetts. When Rachel was 14 years old, her father left her family. Rachel went to Commercial High School, but later switched to Central High School because her mother wanted ...
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World War I
World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fighting occurring throughout Europe, the Middle East, Africa, the Pacific, and parts of Asia. An estimated 9 million soldiers were killed in combat, plus another 23 million wounded, while 5 million civilians died as a result of military action, hunger, and disease. Millions more died in genocides within the Ottoman Empire and in the 1918 influenza pandemic, which was exacerbated by the movement of combatants during the war. Prior to 1914, the European great powers were divided between the Triple Entente (comprising France, Russia, and Britain) and the Triple Alliance (containing Germany, Austria-Hungary, and Italy). Tensions in the Balkans came to a head on 28 June 1914, following the assassination of Archduke Franz Ferdin ...
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Chemical Pioneer Award
The Chemical Pioneer Award, established in 1966, is awarded by the American Institute of Chemists to recognize chemists or chemical engineers who have made outstanding contributions to advances in chemistry or the chemical profession. Recent recipients SourceAIC* 2022 Alison Butler, Chi-Huey Wong * 2021 Benjamin Cravatt, Veronica Vaida, Jonathan L. Sessler * 2020 ''No award'' * 2019 William H. Starnes, Jr., Peng Chen, Richard B. Kaner *2018 Kenneth S. Suslick (University of Illinois at Urbana-Champaign); Vicki H. Grassian (UC San Diego); Mercouri Kanatzidis (Northwestern University) *2017 Paul A. Craig (Rochester Institute of Technology); Jeffrey W. Kelly ( Scripps Research Institute); Marek W. Urban (Clemson University) *2016 Rebecca L. Cann (University of Hawaii at Manoa) ; Donna Blackmond (The Scripps Research Institute); Michael Wasielewski (Northwestern University) *2015 ''No award'' *2014 Anthony Cheetham (University of Cambridge, England) ; Ann M. Val ...
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Bristol-Myers Squibb
The Bristol Myers Squibb Company (BMS) is an American multinational pharmaceutical company. Headquartered in New York City, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the largest U.S. corporations. For fiscal 2021, it had a total revenue of $46.4 billion. Bristol Myers Squibb manufactures prescription pharmaceuticals and biologics in several therapeutic areas, including cancer, HIV/AIDS, cardiovascular disease, diabetes, hepatitis, rheumatoid arthritis, and psychiatric disorders. BMS's primary research and development (R&D) sites are located in Lawrence, New Jersey (formerly Squibb, near Princeton), Summit, New Jersey, formerly HQ of Celgene, New Brunswick, New Jersey, Redwood City, California, and Seville in Spain, with other sites in Devens and Cambridge, Massachusetts, East Syracuse, New York, Braine-l'Alleud, Belgium, Tokyo, Japan, Bangalore, India, and Wirral, United Kingdom. BMS previously had ...
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ...
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United States National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scie ...
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Candidiasis
Candidiasis is a fungal infection due to any type of '' Candida'' (a type of yeast). When it affects the mouth, in some countries it is commonly called thrush. Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. Other symptoms may include soreness and problems swallowing. When it affects the vagina, it may be referred to as a yeast infection or thrush. Signs and symptoms include genital itching, burning, and sometimes a white "cottage cheese-like" discharge from the vagina. Yeast infections of the penis are less common and typically present with an itchy rash. Very rarely, yeast infections may become invasive, spreading to other parts of the body. This may result in fevers along with other symptoms depending on the parts involved. More than 20 types of ''Candida'' can cause infection with ''Candida albicans'' being the most common. Infections of the mouth are most common among children less than one month old, the elderly, and those ...
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Cryptococcus Neoformans
''Cryptococcus neoformans'' is an encapsulated yeast belonging to the class Tremellomycetes and an obligate aerobe that can live in both plants and animals. Its teleomorph is a filamentous fungus, formerly referred to ''Filobasidiella neoformans''. In its yeast state, it is often found in bird excrement. ''Cryptococcus neoformans'' can cause disease in apparently immunocompetent, as well as immunocompromised, hosts. Classification ''Cryptococcus neoformans'' has undergone numerous nomenclature revisions since its first description in 1895. It formerly contained two varieties: ''C. neoformans ''var.'' neoformans'' and ''C. neoformans '' var.'' grubii''. A third variety, ''C. neoformans ''var.'' gattii'', was later defined as a distinct species, ''Cryptococcus gattii''. The most recent classification system divides these varieties into seven species. ''C. neoformans'' refers to ''C. neoformans '' var.'' grubii''. A new species name, ''Cryptococcus deneoformans'', is used for the f ...
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Candida Albicans
''Candida albicans'' is an opportunistic pathogenic yeast that is a common member of the human gut flora. It can also survive outside the human body. It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults. It is usually a commensal organism, but it can become pathogenic in immunocompromised individuals under a variety of conditions. It is one of the few species of the genus '' Candida'' that causes the human infection candidiasis, which results from an overgrowth of the fungus. Candidiasis is, for example, often observed in HIV-infected patients. ''C. albicans'' is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. ''C. albicans'', ''C. tropicalis'', ''C. parapsilosis'', and ''C. glabrata'' are together responsible for 50–90% of all cases of candidiasis in humans. A mortality rate of 40% has been reported for patients with systemic candidiasis due to ''C. albicans''. ...
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Actinomycetes
The Actinomycetales is an order of Actinomycetota. A member of the order is often called an actinomycete. Actinomycetales are generally gram-positive and anaerobic and have mycelia in a filamentous and branching growth pattern. Some actinomycetes can form rod- or coccoid-shaped forms, while others can form spores on aerial hyphae. Actinomycetales bacteria can be infected by bacteriophages, which are called actinophages. Actinomycetales can range from harmless bacteria to pathogens with resistance to antibiotics. Reproduction Actinomycetales have 2 main forms of reproduction: spore formation and hyphae fragmentation. During reproduction, Actinomycetales can form conidiophores, sporangiospores, and oidiospores. In reproducing through hyphae fragmentation, the hyphae formed by Actinomycetales can be a fifth to half the size of fungal hyphae, and bear long spore chains. Presence and associations Actinomycetales can be found mostly in soil and decaying organic matter, as well as in ...
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Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ...
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