Eckard Wimmer
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Eckard Wimmer
Eckard Wimmer (born 22 May 1936) is a German American virologist, organic chemist and distinguished professor of molecular genetics and microbiology at Stony Brook University. He is best known for his seminal work on the molecular biology of poliovirus and the first chemical synthesis of a viral genome capable of infection and subsequent production of live viruses. Life and career Eckard Albert Friedrich Wimmer was born on May 22, 1936, in Berlin, Germany. At the onset of World War II, Wimmer at age three lost his father; at age nine, his mother fled together with his two older brothers to Saxony, East Germany, where he finished elementary school and high school. He studied Chemistry at the University of Rostock from 1953 to 1956, and then fled to West Germany to continue his Chemistry studies at University of Göttingen. In 1962 he earned the degree of Doctor rerum naturalium (Dr. rer. nat.) in the Organic Chemistry of natural products under the guidance of Hans Brockmann ...
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Berlin
Berlin ( , ) is the capital and largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's most populous city, according to population within city limits. One of Germany's sixteen constituent states, Berlin is surrounded by the State of Brandenburg and contiguous with Potsdam, Brandenburg's capital. Berlin's urban area, which has a population of around 4.5 million, is the second most populous urban area in Germany after the Ruhr. The Berlin-Brandenburg capital region has around 6.2 million inhabitants and is Germany's third-largest metropolitan region after the Rhine-Ruhr and Rhine-Main regions. Berlin straddles the banks of the Spree, which flows into the Havel (a tributary of the Elbe) in the western borough of Spandau. Among the city's main topographical features are the many lakes in the western and southeastern boroughs formed by the Spree, Havel and Dahme, the largest of which is Lake Müggelsee. Due to its l ...
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West Germany
West Germany is the colloquial term used to indicate the Federal Republic of Germany (FRG; german: Bundesrepublik Deutschland , BRD) between its formation on 23 May 1949 and the German reunification through the accession of East Germany on 3 October 1990. During the Cold War, the western portion of Germany and the associated territory of West Berlin were parts of the Western Bloc. West Germany was formed as a political entity during the Allied occupation of Germany after World War II, established from eleven states formed in the three Allied zones of occupation held by the United States, the United Kingdom, and France. The FRG's provisional capital was the city of Bonn, and the Cold War era country is retrospectively designated as the Bonn Republic. At the onset of the Cold War, Europe was divided between the Western and Eastern blocs. Germany was divided into the two countries. Initially, West Germany claimed an exclusive mandate for all of Germany, representing itself as t ...
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Long Island, NY
Long Island is a densely populated island in the southeastern region of the U.S. state of New York, part of the New York metropolitan area. With over 8 million people, Long Island is the most populous island in the United States and the 18th-most populous in the world. The island begins at New York Harbor approximately east of Manhattan Island and extends eastward about into the Atlantic Ocean and 23 miles wide at its most distant points. The island comprises four counties: Kings and Queens counties (the New York City boroughs of Brooklyn and Queens, respectively) and Nassau County share the western third of the island, while Suffolk County occupies the eastern two thirds of the island. More than half of New York City's residents (58.4%) lived on Long Island as of 2020, in Brooklyn and in Queens. Culturally, many people in the New York metropolitan area colloquially use the term "Long Island" (or "the Island") to refer exclusively to Nassau and Suffolk counties, and convers ...
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Missouri
Missouri is a U.S. state, state in the Midwestern United States, Midwestern region of the United States. Ranking List of U.S. states and territories by area, 21st in land area, it is bordered by eight states (tied for the most with Tennessee): Iowa to the north, Illinois, Kentucky and Tennessee to the east, Arkansas to the south and Oklahoma, Kansas and Nebraska to the west. In the south are the Ozarks, a forested highland, providing timber, minerals, and recreation. The Missouri River, after which the state is named, flows through the center into the Mississippi River, which makes up the eastern border. With more than six million residents, it is the List of U.S. states and territories by population, 19th-most populous state of the country. The largest urban areas are St. Louis, Kansas City, Missouri, Kansas City, Springfield, Missouri, Springfield and Columbia, Missouri, Columbia; the Capital city, capital is Jefferson City, Missouri, Jefferson City. Humans have inhabited w ...
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Saint Louis University School Of Medicine
Saint Louis University School of Medicine is a private, Jesuit medical school. Part of Saint Louis University, the institution was established in 1836. The school has an enrollment of around 700, with about 550 faculty members and 550 residents in 48 graduate medical education programs including residencies, subspecialty residencies and fellowships. The institution centers its research in five specific areas: cancer, infectious disease, liver disease, aging/neurological disorders, and heart/lung disease. Cardinal Glennon Children's Hospital and Saint Louis University Hospital are the two main affiliated teaching hospitals of the school. History Early years Saint Louis University School of Medicine was established in 1836 as the Saint Louis University Medical Department, but no active teaching occurred until 1841. The Know-Nothing movement, an anti-immigrant and subsequently anti Catholic movement that surged through the United States in the 1840s and 1850s eventually led to the s ...
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Poliovirus
A poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species ''Enterovirus C'', in the family of ''Picornaviridae''. There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA (+ssRNA) genome that is about 7500 nucleotides long. The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only RNA and a nonenveloped icosahedral protein coat that encapsulates it—poliovirus is widely regarded as the simplest significant virus. Poliovirus was first isolated in 1909 by Karl Landsteiner and Erwin Popper. The structure of the virus was first elucidated in 1958 using X-ray diffraction by a team at Birkbeck College led by Rosalind Franklin, showing the polio virus to have icosahedral symmetry. In 1981, the poliovirus genome was published by two different teams ...
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David Baltimore
David Baltimore (born March 7, 1938) is an American biologist, university administrator, and 1975 Nobel laureate in Physiology or Medicine. He is President Emeritus and Distinguished Professor of Biology at the California Institute of Technology (Caltech), where he served as president from 1997 to 2006. He also served as the director of the Joint Center for Translational Medicine, which joined Caltech and UCLA in a program to translate basic scientific discoveries into clinical realities. He also formerly served as president of Rockefeller University from 1990 to 1991, founder and director of the Whitehead Institute of Biomedical Research from 1982 to 1990, and was president of the American Association for the Advancement of Science in 2007. Baltimore has profoundly influenced international science, including key contributions to immunology, virology, cancer research, biotechnology, and recombinant DNA research, through his accomplishments as a researcher, administrator, educat ...
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University Of Illinois
The University of Illinois Urbana-Champaign (U of I, Illinois, University of Illinois, or UIUC) is a public land-grant research university in Illinois in the twin cities of Champaign and Urbana. It is the flagship institution of the University of Illinois system and was founded in 1867. Enrolling over 56,000 undergraduate and graduate students, the University of Illinois is one of the largest public universities by enrollment in the country. The University of Illinois Urbana-Champaign is a member of the Association of American Universities and is classified among "R1: Doctoral Universities – Very high research activity". In fiscal year 2019, research expenditures at Illinois totaled $652 million. The campus library system possesses the second-largest university library in the United States by holdings after Harvard University. The university also hosts the National Center for Supercomputing Applications and is home to the fastest supercomputer on a university campus. The u ...
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Transfer RNA
Transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length (in eukaryotes), that serves as the physical link between the mRNA and the amino acid sequence of proteins. tRNAs genes from Bacteria are typically shorter (mean = 77.6 bp) than tRNAs from Archaea (mean = 83.1 bp) and eukaryotes (mean = 84.7 bp). The mature tRNA follows an opposite pattern with tRNAs from Bacteria being usually longer (median = 77.6 nt) than tRNAs from Archaea (median = 76.8 nt), with eukaryotes exhibiting the shortest mature tRNAs (median = 74.5 nt). Transfer RNA (tRNA) does this by carrying an amino acid to the protein synthesizing machinery of a cell called the ribosome. Complementation of a 3-nucleotide codon in a messenger RNA (mRNA) by a 3-nucleotide anticodon of the tRNA results in protein synthesis based on the mRNA code. As such, tRNAs are a necessary component of translation, the biological sy ...
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Vancouver
Vancouver ( ) is a major city in western Canada, located in the Lower Mainland region of British Columbia. As the List of cities in British Columbia, most populous city in the province, the 2021 Canadian census recorded 662,248 people in the city, up from 631,486 in 2016. The Greater Vancouver, Greater Vancouver area had a population of 2.6million in 2021, making it the List of census metropolitan areas and agglomerations in Canada#List, third-largest metropolitan area in Canada. Greater Vancouver, along with the Fraser Valley Regional District, Fraser Valley, comprises the Lower Mainland with a regional population of over 3 million. Vancouver has the highest population density in Canada, with over 5,700 people per square kilometre, and fourth highest in North America (after New York City, San Francisco, and Mexico City). Vancouver is one of the most Ethnic origins of people in Canada, ethnically and Languages of Canada, linguistically diverse cities in Canada: 49.3 percent of ...
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University Of British Columbia
The University of British Columbia (UBC) is a public university, public research university with campuses near Vancouver and in Kelowna, British Columbia. Established in 1908, it is British Columbia's oldest university. The university ranks among the top three universities in Canada. With an annual research budget of $759million, UBC funds over 8,000 projects a year. The Vancouver campus is situated adjacent to the University Endowment Lands located about west of downtown Vancouver. UBC is home to TRIUMF, Canada's national laboratory for Particle physics, particle and nuclear physics, which houses the world's largest cyclotron. In addition to the Peter Wall Institute for Advanced Studies and Stuart Blusson Quantum Matter Institute, UBC and the Max Planck Society collectively established the first Max Planck Institute in North America, specializing in quantum materials. One of the largest research libraries in Canada, the UBC Library system has over 9.9million volumes among it ...
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