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Ebola Virus Disease Treatment Research
There is no cure or specific treatment for the Ebola virus disease that is currently approved for market, although various experimental treatments are being developed. For past and current Ebola epidemics, treatment has been primarily supportive in nature. , two experimental treatments known as atoltivimab/maftivimab/odesivimab and ansuvimab were found to be 90% effective. In October 2020, the U.S. Food and Drug Administration (FDA) approved atoltivimab/maftivimab/odesivimab with an indication for the treatment of infection caused by ''Zaire ebolavirus''. Overview In March 2014, the World Health Organization (WHO) reported a major Ebola outbreak in Guinea, a western African nation. The disease then rapidly spread to the neighboring countries of Liberia and Sierra Leone. The 2014 West African Ebola outbreak is the largest Ebola outbreak ever documented, and the first recorded in the region. The director of the US National Institute of Allergy and Infectious Diseases (NIA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ebola Virus
''Zaire ebolavirus'', more commonly known as Ebola virus (; EBOV), is one of six known species within the genus ''Ebolavirus''. Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD). Ebola virus has caused the majority of human deaths from EVD, and was the cause of the 2013–2016 epidemic in western Africa, which resulted in at least suspected cases and confirmed deaths. Ebola virus and its genus were both originally named for Zaire (now the Democratic Republic of the Congo), the country where it was first described, and was at first suspected to be a new "strain" of the closely related Marburg virus. The virus was renamed "Ebola virus" in 2010 to avoid confusion. Ebola virus is the single member of the species ''Zaire ebolavirus'', which is assigned to the genus ''Ebolavirus'', family ''Filoviridae'', order ''Mononegavirales''. The members of the species are cal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Guardian
''The Guardian'' is a British daily newspaper. It was founded in 1821 as ''The Manchester Guardian'', and changed its name in 1959. Along with its sister papers ''The Observer'' and ''The Guardian Weekly'', ''The Guardian'' is part of the Guardian Media Group, owned by the Scott Trust. The trust was created in 1936 to "secure the financial and editorial independence of ''The Guardian'' in perpetuity and to safeguard the journalistic freedom and liberal values of ''The Guardian'' free from commercial or political interference". The trust was converted into a limited company in 2008, with a constitution written so as to maintain for ''The Guardian'' the same protections as were built into the structure of the Scott Trust by its creators. Profits are reinvested in journalism rather than distributed to owners or shareholders. It is considered a newspaper of record in the UK. The editor-in-chief Katharine Viner succeeded Alan Rusbridger in 2015. Since 2018, the paper's main news ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science News
''Science News (SN)'' is an American bi-weekly magazine devoted to articles about new scientific and technical developments, typically gleaned from recent scientific and technical journals. History ''Science News'' has been published since 1922 by Society for Science & the Public, a non-profit organization founded by E. W. Scripps in 1920. American chemist Edwin Slosson served as the publication's first editor. From 1922 to 1966, it was called ''Science News Letter''. The title was changed to ''Science News'' with the March 12, 1966 issue (vol. 89, no. 11). Tom Siegfried was the editor from 2007 to 2012. In 2012, Siegfried stepped down, and Eva Emerson became the Editor in Chief of the magazine. In 2017, Eva Emerson stepped down to become the editor of a new digital magazine, Annual Reviews. On February 1, 2018 Nancy Shute became the Editor in Chief of the magazine. In April 2008, the magazine changed from a weekly format to the current biweekly format, and the website was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monoclonal Antibody
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell Lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell. Monoclonal antibodies can have monovalent affinity, binding only to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different antibody-secreting plasma cell lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one monoclonal antibody to two epitopes. It is possible to produce monoclonal antibodies that specifically bind to virtually any suitable substance; they can then serve to detect or purify it. This capability has become an investigative tool in biochemistry, molecular biology, and medicine. Monoclonal antibodies are being used on a clinical level for both the diagnosis and therapy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ZMapp
ZMapp is an experimental biopharmaceutical drug comprising three chimeric monoclonal antibodies under development as a treatment for Ebola virus disease. Two of the three components were originally developed at the Public Health Agency of Canada's National Microbiology Laboratory (NML), and the third at the U.S. Army Medical Research Institute of Infectious Diseases; the cocktail was optimized by Gary Kobinger, a research scientist at the NML and underwent further development under license by Mapp Biopharmaceutical. ZMapp was first used on humans during the 2014 West Africa Ebola virus outbreak, having only been previously tested on animals and not yet subjected to a randomized controlled trial. The NIH ran a clinical trial starting in January 2015 with subjects from Sierra Leone, Guinea, and Liberia aiming to enroll 200 people, but the epidemic waned and the trial closed early, leaving it too statistically underpowered to give a meaningful result about whether ZMapp worked. In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Federal Service For Supervision Of Consumer Rights Protection And Human Welfare
The Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (russian: Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека) or Rospotrebnadzor (russian: Роспотребнадзор, link=no) is the federal service responsible for the supervision of consumer rights protection and human wellbeing in Russia. This service was founded in 2004, and was included in the structure of the Ministry of Health Care of Russia until 2012. In May 2012 Rospotrebnadzor was removed from the supervision of the Ministry of Health and now reports directly to the Russian Government. It functions on the authority of the Act of Federal Service on the base of the Administrative Regulation. History The organization's history goes back to the Decree of the Council of People's Commissars of the RSFSR "On the Sanitary Authorities of the Republic" dated 15 September 1922. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rusal
United Company RUSAL, international public joint-stock company (russian: МКПАО «ОК РУСАЛ», MKPAO «ОК RUSAL») is the world's second largest aluminium company by primary production output (as of 2016). It was the largest until overtaken by China Hongqiao Group in 2015. UC RUSAL accounts for almost 9% of the world's primary aluminium output and 9% of the world's alumina production. The United Company was formed by the merger of RUSAL (Russkiy alyuminiy, lit. Russian aluminium) (russian: Русский алюминий), SUAL, and the alumina assets of Glencore, completed in March 2007. According to its own statistics, UC Rusal accounts for 6.2% of the world's primary aluminium output and 6.5% of the world's alumina production, while operating assets in 13 countries over five continents, employing over 61,000 people across its international operations and offices. The company is incorporated in Jersey, where it has its financial centre, but its headquarters are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kindia Region
Kindia Region (Pular language, Pular: 𞤁𞤭𞥅𞤱𞤢𞤤 𞤑𞤭𞤲𞤣𞤭𞤴𞤢𞥄) is located in western Guinea. It is bordered by the country of Sierra Leone and the Guinean regions of Conakry Region, Conakry, Labé Region, Labé, Mamou Region, Mamou, and Boké Region, Boké. Administrative divisions Kindia Region is divided into five prefectures; which are further sub-divided into 45 sub-prefectures: * Coyah Prefecture (4 sub-prefectures) * Dubréka Prefecture (7 sub-prefectures) * Forécariah Prefecture (10 sub-prefectures) * Kindia Prefecture (10 sub-prefectures) * Télimélé Prefecture (14 sub-prefectures) References Kindia Region, Regions of Guinea {{Guinea-geo-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scripps Research Institute
Scripps Research, previously known as The Scripps Research Institute (TSRI), is a nonprofit American medical research facility that focuses on research and education in the biomedical sciences. Headquartered in San Diego, California, the institute has over 170 laboratories employing 2,100 scientists, technicians, graduate students, and administrative and other staff, making it the largest private, non-profit biomedical research organization in the United States and among the largest in the world. The institute holds over 1,100 patents, has produced 11 FDA-approved therapeutics, and has generated over 50 spin-off companies. According to the 2017 Nature Innovation Index, Scripps Research is the #1 most influential research institution in the world. The Scripps Research graduate program is ranked 9th nationally in the biological sciences, 6th for organic chemistry, and 6th for biochemistry. In 2022, their Jupiter, FL campus became a part of the University of Florida. Jupiter-base ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Community Grid
World Community Grid (WCG) is an effort to create the world's largest volunteer computing platform to tackle scientific research that benefits humanity. Launched on November 16, 2004, with proprietary Grid MP client from United Devices and adding support for Berkeley Open Infrastructure for Network Computing (BOINC) in 2005, World Community Grid eventually discontinued the Grid MP client and consolidated on the BOINC platform in 2008. In September 2021, it was announced that IBM transferred ownership to the Krembil Research Institute of University Health Network in Toronto, Ontario. World Community Grid utilizes unused processing power of consumer devices (PCs, Laptops, Android Smartphones, etc.) to analyse data created by the research groups that participate in the grid. WCG projects have analysed data related to the human genome, the human microbiome, HIV, dengue, muscular dystrophy, cancer, influenza, Ebola, Zika virus, virtual screening, rice crop yields, clean energy, water ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Outsmart Ebola Together
World Community Grid (WCG) is an effort to create the world's largest volunteer computing platform to tackle scientific research that benefits humanity. Launched on November 16, 2004, with proprietary Grid MP client from United Devices and adding support for Berkeley Open Infrastructure for Network Computing (BOINC) in 2005, World Community Grid eventually discontinued the Grid MP client and consolidated on the BOINC platform in 2008. In September 2021, it was announced that IBM transferred ownership to the Krembil Research Institute of University Health Network in Toronto, Ontario. World Community Grid utilizes unused processing power of consumer devices (PCs, Laptops, Android Smartphones, etc.) to analyse data created by the research groups that participate in the grid. WCG projects have analysed data related to the human genome, the human microbiome, HIV, dengue, muscular dystrophy, cancer, influenza, Ebola, Zika virus, virtual screening, rice crop yields, clean energy, water ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Distributed Computing
A distributed system is a system whose components are located on different computer network, networked computers, which communicate and coordinate their actions by message passing, passing messages to one another from any system. Distributed computing is a field of computer science that studies distributed systems. The components of a distributed system interact with one another in order to achieve a common goal. Three significant challenges of distributed systems are: maintaining concurrency of components, overcoming the clock synchronization, lack of a global clock, and managing the independent failure of components. When a component of one system fails, the entire system does not fail. Examples of distributed systems vary from service-oriented architecture, SOA-based systems to massively multiplayer online games to peer-to-peer, peer-to-peer applications. A computer program that runs within a distributed system is called a distributed program, and ''distributed programming' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
