Extramacrochaetae
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Extramacrochaetae
The gene ''extramachrochaetae (emc)'' is a ''Drosophila melanogaster'' gene that codes for the Emc protein, which has a wide variety of developmental roles. It was named, as is common for ''Drosophila'' genes, after the phenotypic change caused by a mutation in the gene (macrochaetae are the longer bristles on ''Drosophila''). The ''emc'' gene The ''emc'' gene is located near the tip of the left arm of the 3rd ''Drosophila'' chromosome. It is about 4100 base pairs long, including two exons and one intron. Its FlyBase designation is Dmel_emc, and its location is at 3L:749,406..753,505 [+]. 86 alleles have been reported. Emc interactions with other proteins The Emc protein has a helix-loop-helix protein domain without the basic region, making it unable to bind to DNA and act as a transcription factor. It does, however, have the ability to bind other basic helix-loop-helix domain-containing proteins, such as the products of the Achaete-scute complex, ''achaete-scute'' complex ...
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Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly" or "pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, and othe ...
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