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Eugen Von Hippel
Eugen Adolf Arthur von Hippel (3 August 1867 – 4 July 1939) was a German ophthalmologist born in Königsberg. Family Eugen is the son of Arthur von Hippel (physician), brother of Robert von Hippel and Richard von Hippel, and uncle of Arthur R. von Hippel. Early life, education, and training He studied medicine in Heidelberg under ophthalmologist Theodor Leber (1840–1917) and neurologist Wilhelm Heinrich Erb (1840–1921). Career In 1897, Hippel attained the title of "professor extraordinary" at Heidelberg, and in 1909 became a professor at the eye clinic in Halle. In 1914, he became a professor of ophthalmology in Göttingen. In 1904, Hippel described a rare disorder of the retina, and in 1911 discovered the anatomical basis of this disease, which he named "angiomatosis retinae". However it wasn't until 1926 that Swedish pathologist Arvid Lindau recognized an association between angiomatosis of the retina with hemangioblastomas of the cerebellum and other parts of the cen ...
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Voit 206 Eugen V
Voit (official name: "Industrias Voit S.A. de C.V.") is a sports equipment manufacturing company based in Mexico. The company was founded by German American entrepreneur William J. Voit (1880–1946) of Worthington, Indiana. Current range of products by Voit includes mainly balls (for association and American football, basketball and volleyball), and also goalkeeper gloves, tennis rackets, football uniforms, shin guards, and swimming equipment ( suits, goggles, caps, and fins) and accessories (backpacks, bags). History Voit began in Los Angeles in 1922 as a tire retreading products factory. In the late 1920s Voit developed and patented the first full-molded, all-rubber inflatable ball and the first needle-type air retention valves. They also developed highly accurate pocket and wrist watches during this period. In 1931, Voit developed and patented the first all-rubber athletic balls, including the process of vulcanization which allowed a material to be fixed onto a separate ...
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Angiomatosis
Angiomatosis is a non-neoplastic condition characterised by nests of proliferating capillaries arranged in a lobular pattern, displacing adjacent muscle and fat. It consists of many angiomas. These tend to be cavernous hemangiomas, which are sharply defined, sponge-like tumors composed of large, dilated, cavernous vascular spaces. Presentation Associated They often appear in: * Von Hippel–Lindau disease: It can be associated with Von Hippel–Lindau disease and is a rare genetic multi-system disorder characterized by the abnormal growth of tumours in the body. Symptoms may include headaches, problems with balance and walking, dizziness, weakness of the limbs, vision problems and high blood pressure. * Bacillary angiomatosis * Klippel–Trénaunay syndrome * Sturge–Weber syndrome Histology It is a vascular malformation wherein blood vessels proliferate along with accompanying mature fat and fibrous tissue, lymphatics and sometimes nerves. They may involve skin, subcutaneous tis ...
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Physicians From Königsberg
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ...
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German Ophthalmologists
German(s) may refer to: * Germany (of or related to) **Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Germanic peoples (Roman times) * German language **any of the Germanic languages * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (other) * Germa ...
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1939 Deaths
This year also marks the start of the Second World War, the largest and deadliest conflict in human history. Events Below, the events of World War II have the "WWII" prefix. January * January 1 ** Third Reich *** Jews are forbidden to work with Germans. *** The Youth Protection Act was passed on April 30, 1938 and the Working Hours Regulations came into effect. *** The Jews name change decree has gone into effect. ** The rest of the world *** In Spain, it becomes a duty of all young women under 25 to complete compulsory work service for one year. *** First edition of the Vienna New Year's Concert. *** The company of technology and manufacturing scientific instruments Hewlett-Packard, was founded in a garage in Palo Alto, California, by William (Bill) Hewlett and David Packard. This garage is now considered the birthplace of Silicon Valley. *** Sydney, in Australia, records temperature of 45 ˚C, the highest record for the city. *** Philipp Etter took over as Swi ...
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1867 Births
Events January–March * January 1 – The Covington–Cincinnati Suspension Bridge opens between Cincinnati, Ohio, and Covington, Kentucky, in the United States, becoming the longest single-span bridge in the world. It was renamed after its designer, John A. Roebling, in 1983. * January 8 – African-American men are granted the right to vote in the District of Columbia. * January 11 – Benito Juárez becomes Mexican president again. * January 30 – Emperor Kōmei of Japan dies suddenly, age 36, leaving his 14-year-old son to succeed as Emperor Meiji. * January 31 – Maronite nationalist leader Youssef Bey Karam leaves Lebanon aboard a French ship for Algeria. * February 3 – ''Shōgun'' Tokugawa Yoshinobu abdicates, and the late Emperor Kōmei's son, Prince Mutsuhito, becomes Emperor Meiji of Japan in a brief ceremony in Kyoto, ending the Late Tokugawa shogunate. * February 7 – West Virginia University is established in Morgantown, West Virginia. * Febru ...
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Von Hippel–Lindau Tumor Suppressor
) hockey league, Supreme Hockey League The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that, in humans, is encoded by the ''VHL'' gene. Mutations of the VHL gene are associated with Von Hippel–Lindau disease. Function The protein encoded by the VHL gene is the substrate recognition component of a protein complex that includes elongin B, elongin C, and cullin-2, and possesses E3 ubiquitin ligase activity. This complex is involved in the ubiquitination and subsequent degradation of hypoxia-inducible factors (HIFs), which are transcription factors that play a central role regulating gene expression in response to changing oxygen levels. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. The resultant protein is produced in two forms, an 18 kDa and a 30 kDa protein that functions as a tumor suppressor. The main action of the VH ...
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Physicist
A physicist is a scientist who specializes in the field of physics, which encompasses the interactions of matter and energy at all length and time scales in the physical universe. Physicists generally are interested in the root or ultimate causes of phenomena, and usually frame their understanding in mathematical terms. Physicists work across a wide range of research fields, spanning all length scales: from sub-atomic and particle physics, through biological physics, to cosmological length scales encompassing the universe as a whole. The field generally includes two types of physicists: experimental physicists who specialize in the observation of natural phenomena and the development and analysis of experiments, and theoretical physicists who specialize in mathematical modeling of physical systems to rationalize, explain and predict natural phenomena. Physicists can apply their knowledge towards solving practical problems or to developing new technologies (also known as applie ...
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Corneal Transplantation
Corneal transplantation, also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced by donated corneal tissue (the graft). When the entire cornea is replaced it is known as penetrating keratoplasty and when only part of the cornea is replaced it is known as lamellar keratoplasty. Keratoplasty simply means surgery to the cornea. The graft is taken from a recently deceased individual with no known diseases or other factors that may affect the chance of survival of the donated tissue or the health of the recipient. The cornea is the transparent front part of the eye that covers the iris, pupil and anterior chamber. The surgical procedure is performed by ophthalmologists, physicians who specialize in eyes, and is often done on an outpatient basis. Donors can be of any age, as is shown in the case of Janis Babson, who donated her eyes after dying at the age of 10. Corneal transplantation is performed when medicines, keratoconus conservat ...
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Anatomy
Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. Anatomy is inherently tied to developmental biology, embryology, comparative anatomy, evolutionary biology, and phylogeny, as these are the processes by which anatomy is generated, both over immediate and long-term timescales. Anatomy and physiology, which study the structure and function (biology), function of organisms and their parts respectively, make a natural pair of related disciplines, and are often studied together. Human anatomy is one of the essential basic research, basic sciences that are applied in medicine. The discipline of anatomy is divided into macroscopic scale, macroscopic and microscopic scale, microscopic. Gross anatomy, Macroscopic anatomy, or gross anatomy, is the examination of an ...
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Von Hippel–Lindau Disease
Von Hippel–Lindau disease (VHL), also known as Von Hippel–Lindau syndrome, is a rare genetic disorder with multisystem involvement. It is characterized by visceral cysts and benign tumors with potential for subsequent malignant transformation. It is a type of phakomatosis that results from a mutation in the Von Hippel–Lindau tumor suppressor gene on chromosome 3p25.3. Signs and symptoms Signs and symptoms associated with VHL disease include headaches, problems with balance and walking, dizziness, weakness of the limbs, vision problems, and high blood pressure. Conditions associated with VHL disease include angiomatosis, hemangioblastomas, pheochromocytoma, renal cell carcinoma, pancreatic cysts (pancreatic serous cystadenoma), endolymphatic sac tumor, and bilateral papillary cystadenomas of the epididymis (men) or broad ligament of the uterus (women). Angiomatosis occurs in 37.2% of patients presenting with VHL disease and usually occurs in the retina. As a result, loss ...
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Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts. It is a structure composed of nervous tissue positioned along the rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain (precursor structures exist in onychophorans, gastropods and lancelets). The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal cord are both enclosed in the meninges. The meninges provide a barrier to chemicals dissolv ...
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