Ethyldichloroarsine
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Ethyldichloroarsine
Ethyldichloroarsine, sometimes abbreviated "ED" and also known as ethyl Dick, is an organoarsenic compound with the formula CH3CH2AsCl2. This colourless volatile liquid is a highly toxic obsolete vesicant or blister agent A blister agent (or vesicant), is a chemical compound that causes severe skin, eye and mucosal pain and irritation. They are named for their ability to cause severe chemical burns, resulting in painful water blisters on the bodies of those affe ... that was used during World War I in chemical warfare. The molecule is pyramidal with the Cl-As-Cl and C-As-Cl angles approaching 90° (see image). Ethyldichloroarsine has high chronic toxicity, similar to lewisite. References {{Chemical warfare Arsenical vesicants Organoarsenic chlorides ...
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Arsenical Vesicants
Arsenicals are chemical compounds that contain arsenic. In a military context, the term arsenical refer to toxic arsenic compounds that are used as chemical warfare agents. This include blister agents, blood agents and vomiting agents. Examples Blister agents *Ethyldichloroarsine *Lewisite *Methyldichloroarsine *Phenyldichloroarsine Blood agents *Arsine Vomiting agents *Adamsite *Diphenylchlorarsine *Diphenylcyanoarsine *Phenyldichloroarsine Phenyldichloroarsine, also known by its wartime name phenyl Dick and its NATO abbreviation PD, is an organic arsenical vesicant and vomiting agent developed by Germany and France for use as a chemical warfare agent during World War I. The agent i ... References Arsenic compounds Chemical weapons Poisons {{Chem-stub ...
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Toxicity
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell ( cytotoxicity) or an organ such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or society at large. Sometimes the word is more or less synonymous with poisoning in everyday usage. A central concept of toxicology is that the effects of a toxicant are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypas ...
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Irritant (biology)
Irritation, in biology and physiology, is a state of inflammation or painful reaction to allergy or cell-lining damage. A stimulus or agent which induces the state of irritation is an irritant. Irritants are typically thought of as chemical agents (for example phenol and capsaicin) but mechanical, thermal (heat), and radiative stimuli (for example ultraviolet light or ionising radiations) can also be irritants. Irritation also has non-clinical usages referring to bothersome physical or psychological pain or discomfort. Irritation can also be induced by some allergic response due to exposure of some allergens for example contact dermatitis, irritation of mucosal membranes and pruritus. Mucosal membrane is the most common site of irritation because it contains secretory glands that release mucous which attracts the allergens due to its sticky nature. Chronic irritation is a medical term signifying that afflictive health conditions have been present for a while. There are many dis ...
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Organoarsenic Chemistry
Organoarsenic chemistry is the chemistry of compounds containing a chemical bond between arsenic and carbon. A few organoarsenic compounds, also called "organoarsenicals," are produced industrially with uses as insecticides, herbicides, and fungicides. In general these applications are declining in step with growing concerns about their impact on the environment and human health. The parent compounds are arsane and arsenic acid. Despite their toxicity, organoarsenic biomolecules are well known. History 140px, Cacodyl (tetramethyldiarsine) was one of the first organoarsenic compounds. Surprising for an area now considered of minor importance, organoarsenic chemistry played a prominent role in the history of the field of chemistry. The oldest known organoarsenic compound, the foul smelling cacodyl was reported in "cacodyl" (1760) and is sometimes classified as the first synthetic organometallic compound. The compound Salvarsan was one of the first pharmaceuticals, earning a Nobel ...
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Vesicant
A blister agent (or vesicant), is a chemical compound that causes severe skin, eye and mucosal pain and irritation. They are named for their ability to cause severe chemical burns, resulting in painful water blisters on the bodies of those affected. Although the term is often used in connection with large-scale burns caused by chemical spills or chemical warfare agents,Center for Disease Control
some naturally occurring substances such as are also blister-producing agents (vesicants).
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Blister Agent
A blister agent (or vesicant), is a chemical compound that causes severe skin, eye and mucosal pain and irritation. They are named for their ability to cause severe chemical burns, resulting in painful water blisters on the bodies of those affected. Although the term is often used in connection with large-scale burns caused by chemical spills or chemical warfare agents,Center for Disease Control
some naturally occurring substances such as are also blister-producing agents (vesicants).
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Chemical Warfare
Chemical warfare (CW) involves using the toxic properties of chemical substances as weapons. This type of warfare is distinct from nuclear warfare, biological warfare and radiological warfare, which together make up CBRN, the military acronym for chemical, biological, radiological, and nuclear (warfare or weapons), all of which are considered "weapons of mass destruction" (WMDs), a term that contrasts with conventional weapons. The use of chemical weapons is prohibited under customary international humanitarian law. Definition Chemical warfare is different from the use of conventional weapons or nuclear weapons because the destructive effects of chemical weapons are not primarily due to any explosive force. The offensive use of living organisms (such as anthrax) is considered biological warfare rather than chemical warfare; however, the use of nonliving toxic products produced by living organisms (e.g. toxins such as botulinum toxin, ricin, and saxitoxin) ''is'' consider ...
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Lewisite
Lewisite (L) (A-243) is an organoarsenic compound. It was once manufactured in the U.S., Japan, Germany and the Soviet Union for use as a Chemical warfare, chemical weapon, acting as a vesicant (blister agent) and lung irritant. Although the substance is colorless and odorless in its pure form, impure samples of lewisite are a yellow, brown, violet-black, green, or amber oily liquid with a distinctive odor that has been described as similar to Pelargonium, geraniums. Chemical reactions The compound is prepared by the addition of arsenic trichloride to acetylene in the presence of a suitable catalyst: :AsCl3 + C2H2 → ClCHCHAsCl2 (Lewisite) Lewisite, like other arsenous chlorides, hydrolysis, hydrolyses in water to form hydrochloric acid and chlorovinylarsenous oxide (a less-powerful blister agent): :ClCHCHAsCl2 + 2 H2O → ClCHCHAs(OH)2 + 2 HCl This reaction is accelerated in alkaline solutions, and forms acetylene and trisodium arsenate. Lewisite reacts with metals to form hydrog ...
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